Spontaneous Regression was.... Why is my PSA Fluctuating?

[Guest guest]

Rich you say:

<snip> There is

increasing evidence that cancerous cells such as those found in the prostate

and the breast may come and go. <snip>

I’ve long been interested in the

concept of spontaneous regression – for an exchange on the subject you

might like to go along here http://tinyurl.com/SponRegression

Do you have any references other than any mentioned

in that exchange which would be of interest to me/us?

All the best

Prostate men need enlightening, not

frightening

Terry Herbert - diagnosed in 1996 and

still going strong

Read A Strange Place for unbiased information at http://www.yananow.org/StrangePlace/index.html

From:

ProstateCancerSupport

[mailto:ProstateCancerSupport ] On Behalf Of Rich

Sent: Thursday, 27 January 2011

2:35 PM

To:

ProstateCancerSupport

Subject:

Re: Why is my PSA Fluctuating?

As Terry noted, PSA can vary and a daily variation range of +/_20% is

not unreasonable. When charting my PSA, I normalize the results by averaging

the most recent three samples then plotting the values. Graphing is useful to

monitor PSA velocity, that is, rate of change.

Also keep in mind that grading tissue samples is a judgment items based on

illustrative samples. As in any such grading there will be marginal variations

that the evaluator must judge one way or the other.

Also, you show at least one result with PIN,in your case listed as High Grade.

LG and HGPIN express much higher levels of PSA and other markers used to date

at far higher levels than benign tissue. That is one reason for the loss of

popularity of PCA3 as a marker for prostate cancer among other issues.

There is increasing evidence that cancerous cells such as those found in the

prostate and the breast may come and go.

Finally, ejaculations and massage of the prostate (eg bicycle seat) can impact

PSA expression significantly.

Rich Luxton

Green Bay, WI

[Guest guest]

No, Terry, I do not. My remark was made based on general recollection of reading

such report summaries or hearing about it on the popular news, not from a

rigorous review of the literature.

Rich

>

> Rich you say:

>

>

>

> <snip> There is increasing evidence that cancerous cells such as those found

> in the prostate and the breast may come and go. <snip>

>

>

>

> I've long been interested in the concept of spontaneous regression - for an

> exchange on the subject you might like to go along here

> http://tinyurl.com/SponRegression

>

>

>

> Do you have any references other than any mentioned in that exchange which

> would be of interest to me/us?

>

>

>

> All the best

>

> Prostate men need enlightening, not frightening

>

> Terry Herbert - diagnosed in 1996 and still going strong

>

> Read A Strange Place for unbiased information at

> http://www.yananow.org/StrangePlace/index.html

> <http://www.yananow.net/StrangePlace/index.html>

>

>

>

> _____

>

> From: ProstateCancerSupport

> [mailto:ProstateCancerSupport ] On Behalf Of Rich

> Sent: Thursday, 27 January 2011 2:35 PM

> To: ProstateCancerSupport

> Subject: Re: Why is my PSA Fluctuating?

>

>

>

>

>

> As Terry noted, PSA can vary and a daily variation range of +/_20% is not

> unreasonable. When charting my PSA, I normalize the results by averaging the

> most recent three samples then plotting the values. Graphing is useful to

> monitor PSA velocity, that is, rate of change.

>

> Also keep in mind that grading tissue samples is a judgment items based on

> illustrative samples. As in any such grading there will be marginal

> variations that the evaluator must judge one way or the other.

>

> Also, you show at least one result with PIN,in your case listed as High

> Grade. LG and HGPIN express much higher levels of PSA and other markers used

> to date at far higher levels than benign tissue. That is one reason for the

> loss of popularity of PCA3 as a marker for prostate cancer among other

> issues.

>

> There is increasing evidence that cancerous cells such as those found in the

> prostate and the breast may come and go.

>

> Finally, ejaculations and massage of the prostate (eg bicycle seat) can

> impact PSA expression significantly.

>

> Rich Luxton

> Green Bay, WI

>

[Guest guest]

Terry, I do recall the comment being offered in reference to both breast and

prostate cancers but I cannot cite a source.

Rich

>

> Rich you say:

>

>

>

> <snip> There is increasing evidence that cancerous cells such as those found

> in the prostate and the breast may come and go. <snip>

>

>

>

> I've long been interested in the concept of spontaneous regression - for an

> exchange on the subject you might like to go along here

> http://tinyurl.com/SponRegression

>

>

>

> Do you have any references other than any mentioned in that exchange which

> would be of interest to me/us?

>

>

>

> All the best

>

> Prostate men need enlightening, not frightening

>

> Terry Herbert - diagnosed in 1996 and still going strong

>

> Read A Strange Place for unbiased information at

> http://www.yananow.org/StrangePlace/index.html

> <http://www.yananow.net/StrangePlace/index.html>

>

>

>

> _____

>

> From: ProstateCancerSupport

> [mailto:ProstateCancerSupport ] On Behalf Of Rich

> Sent: Thursday, 27 January 2011 2:35 PM

> To: ProstateCancerSupport

> Subject: Re: Why is my PSA Fluctuating?

>

>

>

>

>

> As Terry noted, PSA can vary and a daily variation range of +/_20% is not

> unreasonable. When charting my PSA, I normalize the results by averaging the

> most recent three samples then plotting the values. Graphing is useful to

> monitor PSA velocity, that is, rate of change.

>

> Also keep in mind that grading tissue samples is a judgment items based on

> illustrative samples. As in any such grading there will be marginal

> variations that the evaluator must judge one way or the other.

>

> Also, you show at least one result with PIN,in your case listed as High

> Grade. LG and HGPIN express much higher levels of PSA and other markers used

> to date at far higher levels than benign tissue. That is one reason for the

> loss of popularity of PCA3 as a marker for prostate cancer among other

> issues.

>

> There is increasing evidence that cancerous cells such as those found in the

> prostate and the breast may come and go.

>

> Finally, ejaculations and massage of the prostate (eg bicycle seat) can

> impact PSA expression significantly.

>

> Rich Luxton

> Green Bay, WI

>