Guest guest Posted February 17, 2011 Report Share Posted February 17, 2011 One of the things I've always wondered about with respect to ADT is how they make different doses work. Most drugs I know about have a " half-life " which is the period of time it takes for approximately half of the drug to be broken down in the body. For example, if the half life is 1 day, then if you take 10 mg of a drug, the next day half (5 mg) will be left. The day after, half of that will be left (2.5 mg), the day after that, half again (1.25 mg) and so on. I read recently that the half-life of Lupron is about 3 hours. So how do they get it to work for 30, 90, or 120 days with one injection? Do they inject a timed release formula? The idea would be to chemically bind the Lupron to another chemical that breaks down much more slowly, releasing small amounts of Lupron each day. Does the dose break down quickly, but it is such a large dose that it has a long-lasting effect for 30, 90, or whatever number of days? If anyone knows the answer, I'm very curious to hear it. Thanks. Alan Quote Link to comment Share on other sites More sharing options...
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