Guest guest Posted December 6, 2011 Report Share Posted December 6, 2011 Thanks – very helpful. Anyone interested in the subject might like to have a look at this report which I collected on another Forum http://www.hindawi.com/journals/au/2012/893193/ All the best Prostate men need enlightening, not frightening Terry Herbert - diagnosed in 1996 and still going strong Read A Strange Place for unbiased information at http://www.yananow.org/StrangePlace/index.html From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of C Sent: Wednesday, 7 December 2011 3:47 AM To: ProstateCancerSupport Subject: Re: Nuclear Bone Scan Terry -- From here: http://www.world-nuclear.org/info/inf55.html " The radioisotope most widely used in medicine is technetium-99m, employed in some 80% of all nuclear medicine procedures - hence some 30 million per year, of which 6-7 million are in Europe, 15 million in North America, 6-8 million in Asia/Pacific (particularly Japan), and 0.5 million in other regions. It is an isotope of the artificially-produced element technetium and it has almost ideal characteristics for a nuclear medicine scan. These are: >>> It has a half-life of six hours which is long enough to examine metabolic processes yet short enough to minimise the radiation dose to the patient. <<< Technetium-99m decays by a process called " isomeric " ; which emits gamma rays and low energy electrons. Since there is no high-energy beta emission the radiation dose to the patient is low. The low energy gamma rays it emits easily escape the human body and are accurately detected by a gamma camera. Once again the radiation dose to the patient is minimised. The chemistry of technetium is so versatile it can form tracers by being incorporated into a range of biologically-active substances to ensure that it concentrates in the tissue or organ of interest. Its logistics also favour its use. Technetium generators, a lead pot enclosing a glass tube containing the radioisotope, are supplied to hospitals from the nuclear reactor where the isotopes are made. They contain molybdenum-99, with a half-life of 66 hours, which progressively decays to technetium-99. The Tc-99 is washed out of the lead pot by saline solution when it is required. After two weeks or less the generator is returned for recharging. " FWIW, I think that a four-hour wait, and a six-hour half-life, means that there was enough radiation coming off the technetium to give a good scan result. That's a wild-ass guess. I don't know if the radiologists use " correction factors " for the time between the removal of the Tc from its generator, and the time of the scan. > > I've just had my fourth bone scan, which was clear this time - the last one > had an area 'suspicious for metastasis' which was enough for the oncologist > to accept it as definitive. > > > > But..knowing how inaccurate all scans are, and how busy they were at the > hospital yesterday, a thought struck me and I thought I'd ask for some > input. > > > > I have in the past had the injection of the nuclear material two hours > before the scan. My understanding of the procedure was such that this was > the optimum time for the take up of the material before the material started > to decay as it has a short half life. Yesterday it was four hours before the > scan started and four and a half hours by the time it finished. > > > > I don't know what material was used, but if for example it was > 99mTc-methylene diphosphonate (99mTc-MDP) which seems to be commonly used, > is it likely that the scan's accuracy might be affected by the additional > two hours before the scan was done? > > > > > > All the best > > Prostate men need enlightening, not frightening > > Terry Herbert - diagnosed in 1996 and still going strong > > Read A Strange Place for unbiased information at > http://www.yananow.org/StrangePlace/index.html > <http://www.yananow.net/StrangePlace/index.html> > Quote Link to comment Share on other sites More sharing options...
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