Re: How long does it take for certain lupron effects/side effects to start being red

[Guest guest]

I am not a physician, however it seems to me that a reasonable approach to your question would be to get testosterone levels done since ADT prevents the production of it. That is the criteria I have used. When testosterone returns to normal i would guess that the effects of the ADT have worn off. Good Luck HarrySubject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08

AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)

and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.

Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.

What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both of

a. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ?

(aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after imrt)

and

b. when the lupron effects on bone/muscle density/mass might start to lessen ?

since these effects have happened for sure, at least based on rising

n-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)

(or perhaps should say when lupron effects of testosterone might start to lessen)

(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))

===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.

Thanks.

[Guest guest]

I am not a physician, however it seems to me that a reasonable approach to your question would be to get testosterone levels done since ADT prevents the production of it. That is the criteria I have used. When testosterone returns to normal i would guess that the effects of the ADT have worn off. Good Luck HarrySubject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08

AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)

and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.

Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.

What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both of

a. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ?

(aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after imrt)

and

b. when the lupron effects on bone/muscle density/mass might start to lessen ?

since these effects have happened for sure, at least based on rising

n-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)

(or perhaps should say when lupron effects of testosterone might start to lessen)

(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))

===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.

Thanks.

[Guest guest]

I am not a physician, however it seems to me that a reasonable approach to your question would be to get testosterone levels done since ADT prevents the production of it. That is the criteria I have used. When testosterone returns to normal i would guess that the effects of the ADT have worn off. Good Luck HarrySubject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08

AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)

and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.

Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.

What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both of

a. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ?

(aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after imrt)

and

b. when the lupron effects on bone/muscle density/mass might start to lessen ?

since these effects have happened for sure, at least based on rising

n-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)

(or perhaps should say when lupron effects of testosterone might start to lessen)

(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))

===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.

Thanks.

[Guest guest]

I am not a physician, however it seems to me that a reasonable approach to your question would be to get testosterone levels done since ADT prevents the production of it. That is the criteria I have used. When testosterone returns to normal i would guess that the effects of the ADT have worn off. Good Luck HarrySubject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08

AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)

and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.

Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.

What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both of

a. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ?

(aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after imrt)

and

b. when the lupron effects on bone/muscle density/mass might start to lessen ?

since these effects have happened for sure, at least based on rising

n-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)

(or perhaps should say when lupron effects of testosterone might start to lessen)

(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))

===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.

Thanks.

[Guest guest]

I am not a physician, however it seems to me that a reasonable approach to your question would be to get testosterone levels done since ADT prevents the production of it. That is the criteria I have used. When testosterone returns to normal i would guess that the effects of the ADT have worn off. Good Luck HarrySubject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08

AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)

and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.

Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.

What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both of

a. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ?

(aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after imrt)

and

b. when the lupron effects on bone/muscle density/mass might start to lessen ?

since these effects have happened for sure, at least based on rising

n-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)

(or perhaps should say when lupron effects of testosterone might start to lessen)

(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))

===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.

Thanks.

[Guest guest]

I am not a physician, however it seems to me that a reasonable approach to your question would be to get testosterone levels done since ADT prevents the production of it. That is the criteria I have used. When testosterone returns to normal i would guess that the effects of the ADT have worn off. Good Luck HarrySubject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08

AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)

and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.

Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.

What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both of

a. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ?

(aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after imrt)

and

b. when the lupron effects on bone/muscle density/mass might start to lessen ?

since these effects have happened for sure, at least based on rising

n-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)

(or perhaps should say when lupron effects of testosterone might start to lessen)

(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))

===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.

Thanks.

[Guest guest]

I am not a physician, however it seems to me that a reasonable approach to your question would be to get testosterone levels done since ADT prevents the production of it. That is the criteria I have used. When testosterone returns to normal i would guess that the effects of the ADT have worn off. Good Luck HarrySubject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08

AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)

and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.

Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.

What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both of

a. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ?

(aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after imrt)

and

b. when the lupron effects on bone/muscle density/mass might start to lessen ?

since these effects have happened for sure, at least based on rising

n-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)

(or perhaps should say when lupron effects of testosterone might start to lessen)

(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))

===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.

Thanks.

[Guest guest]

To "themidman5678"

If my 81-year-old memory serves me, after coming off Lupron my testosterone was back into the low normal range in about three months. That was five years ago. I haven't had a recent bone density test, but then I haven't broken anything either - which is good for an geezer. My doctor's recommendation was a calcium citrate/vitamin D supplement and exercise, especially weight-bearing; and I did take his advice. I am still taking the supplement and making regular use (at least three days a week) of a treadmill and free weights.

My prostate cancer was treated seven years ago - 38 IMRT sessions and Lupron/Casodex for about 2.5 years. My PSA has stayed low (0.1 - 0.2) and steady since.

Manny R.

Subject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08 AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both ofa. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ? (aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after

imrt)andb. when the lupron effects on bone/muscle density/mass might start to lessen ?since these effects have happened for sure, at least based on risingn-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)(or perhaps should say when lupron effects of testosterone might start to lessen)(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.Thanks.

[Guest guest]

To "themidman5678"

If my 81-year-old memory serves me, after coming off Lupron my testosterone was back into the low normal range in about three months. That was five years ago. I haven't had a recent bone density test, but then I haven't broken anything either - which is good for an geezer. My doctor's recommendation was a calcium citrate/vitamin D supplement and exercise, especially weight-bearing; and I did take his advice. I am still taking the supplement and making regular use (at least three days a week) of a treadmill and free weights.

My prostate cancer was treated seven years ago - 38 IMRT sessions and Lupron/Casodex for about 2.5 years. My PSA has stayed low (0.1 - 0.2) and steady since.

Manny R.

Subject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08 AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both ofa. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ? (aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after

imrt)andb. when the lupron effects on bone/muscle density/mass might start to lessen ?since these effects have happened for sure, at least based on risingn-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)(or perhaps should say when lupron effects of testosterone might start to lessen)(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.Thanks.

[Guest guest]

To "themidman5678"

If my 81-year-old memory serves me, after coming off Lupron my testosterone was back into the low normal range in about three months. That was five years ago. I haven't had a recent bone density test, but then I haven't broken anything either - which is good for an geezer. My doctor's recommendation was a calcium citrate/vitamin D supplement and exercise, especially weight-bearing; and I did take his advice. I am still taking the supplement and making regular use (at least three days a week) of a treadmill and free weights.

My prostate cancer was treated seven years ago - 38 IMRT sessions and Lupron/Casodex for about 2.5 years. My PSA has stayed low (0.1 - 0.2) and steady since.

Manny R.

Subject: How long does it take for certain lupron effects/side effects to start being redTo: ProstateCancerSupport Date: Friday, July 8, 2011, 2:08 AM

Have finished imrt 44 sessions (gleason 7, 4+3, 3 cores, 3+4, 1 core)and was taking lupron for 6 months covering period before and a bit after imrt -the last monthly shot was 6/15.Am just starting to read about and learn about the next steps as to monitoring psa, psa bounce, tracking hopeful reduction in imrt side effects, when psa results will be valid as to further tracking, etc.What I haven't found in a quick search is when the effects of lupron on psa and testosterone might start to lessen once the full month since the last shot has passed, in the context both ofa. when further psa readings might be valid for future tracking so that the artificially low ones from the lupron don't confuse things ? (aside from other timeline considerations related to psa readings like bounce and other factors which I'm not even aware of yet since have not read anything on the overall topic, wanting to wait until after

imrt)andb. when the lupron effects on bone/muscle density/mass might start to lessen ?since these effects have happened for sure, at least based on risingn-telopeptide ratio readings (and started off with diagnosed osteoporosis even before starting lupron)(or perhaps should say when lupron effects of testosterone might start to lessen)(( am trying to avoid for now the bone medications and use diet/vitamin d/etc to help until I hope the effects of the lupron might wear off))===> I realize the answers to a. and b. will vary widely and that some effects might not reduce or reduce completely, but am just looking for a non technical starting point of information on those questions.Thanks.

[Guest guest]

themidman5678 wrote:

....

> a. when further psa readings might be valid for future tracking

> so that the artificially low ones from the lupron don't confuse

> things ? (aside from other timeline considerations related to

> psa readings like bounce and other factors which I'm not even

> aware of yet since have not read anything on the overall topic,

> wanting to wait until after imrt)

If I remember correctly, my first non-Lupron influenced PSA test

was about 9 months after my last injection. I had tests at

around 3 months and six months and they were both artificially

low (undetectable). The 9 month reading was 0.8.

> b. when the lupron effects on bone/muscle density/mass might

> start to lessen ?

My testosterone levels began to rise maybe four months after the

last injection and reached low normal somewhere around five

months. The hot flushes had stopped by then.

I was not immediately feeling strong and vigorous. I had to

build that back with exercise. Did it come back to exactly where

it was before? I don't think so. But then I'm getting

continuously older and the rust and mileage are accumulating.

It's hard to dissociate the effects of aging from all of this.

I recommend doing as much exercise as you can - even now while

you are still on Lupron. I exercised throughout my Lupron

experience and I believe it made a big difference. My ability to

run dropped dramatically. My best efforts declined from four - 9

minute miles to one 11 minute mile on a treadmill. But I was

still trying and I believe that even that meager performance was

enough to insure that I had enough energy to get through each day

feeling fine and even go on hikes with my wife.

Best of luck.

Alan

[Guest guest]

Alan, Harry, Manny,

Thanks for the feedback and about your experiences - its very helpful

for me.

What I've learned your comments are :

- its the effect of the lowered testosterone that causes at least the

bone/muscle lessening;

(perhaps all lupron side effects are really related to lowered

testosterone, I don't know that yet.)

- that it can take some months, your experiences were 3 to 5 months,

before the testosterone came

back to even low normal range.

- that it can take some months before the effect of lupron on lowering

the psa goes away, so that

psa tests before that happen can still give close to the low results

that were given when lupron was being

taken activelly.

- that keeping up with the exercise now is also important; and Alan's

reference to running reminded me that

even though I'm not able to run and I don't get aerobic from walking,

that it could help me both psycholigically and physically to get back on

the exercise bike and get aerobic, even though its

not the kind of weight bearing exercise like walking that is said to be

good for osteoporosis.

---> I'll need to research further to see if, during the 3-5 months

mentioned for the testosterone to come

back to the low normal range ( starting 30 days after the last monthly

shot) -- if that means the effects of the low testosterone on

bones/muscles will be during those 3-5 months as strong as when the

lupron was being activelly taken or if, during those months, while the

testosterone is slowly increasing on its way to the low normal range,

the effects of the low testosterone on bones/muscles might be lessening.

The reason this is important in my thinking is that it was not until

after the fourth month of the 6 months of lupron shots that the

n-telopeptide readings got bad, even though the testosterone levels had

been very low for 3 of those months and I realize effects of the

lupron/low testosterone are cumulative.

Thus maybe as the testosterone starts to rise during the next 3-5

months, even while still at way below low normal levels, that maybe the

negative effects of it on bones/muscles will start not to be as much.

Or maybe it will take the full 3-5 months for those negative effects to

begin to reverse.

Again, this is in context of seeing if I can avoid taking the bone

medications if and until the months have passed until lupron effects on

testosterone have started to dissipate, and then see if the

n-telopeptide results start coming down. The vitamin D-25 results have

been good thruout the course of the lupron;

I'd started with reading of 18 before taking the D and its gone up now

to about 50, and hope it will

keep getting better.

Thanks again to all - Ken

> ...

> > a. when further psa readings might be valid for future tracking

> > so that the artificially low ones from the lupron don't confuse

> > things ? (aside from other timeline considerations related to

> > psa readings like bounce and other factors which I'm not even

> > aware of yet since have not read anything on the overall topic,

> > wanting to wait until after imrt)

>

> If I remember correctly, my first non-Lupron influenced PSA test

> was about 9 months after my last injection. I had tests at

> around 3 months and six months and they were both artificially

> low (undetectable). The 9 month reading was 0.8.

>

> > b. when the lupron effects on bone/muscle density/mass might

> > start to lessen ?

>

> My testosterone levels began to rise maybe four months after the

> last injection and reached low normal somewhere around five

> months. The hot flushes had stopped by then.

>

> I was not immediately feeling strong and vigorous. I had to

> build that back with exercise. Did it come back to exactly where

> it was before? I don't think so. But then I'm getting

> continuously older and the rust and mileage are accumulating.

> It's hard to dissociate the effects of aging from all of this.

>

> I recommend doing as much exercise as you can - even now while

> you are still on Lupron. I exercised throughout my Lupron

> experience and I believe it made a big difference. My ability to

> run dropped dramatically. My best efforts declined from four - 9

> minute miles to one 11 minute mile on a treadmill. But I was

> still trying and I believe that even that meager performance was

> enough to insure that I had enough energy to get through each day

> feeling fine and even go on hikes with my wife.

>

> Best of luck.

>

> Alan

>