RE: Vivelle Patch 0.025/Confusion/Severe Fatigue/Memory Lapse

June 26, 2012

Jackie,

I don't follow this forum closely, and I just now noticed your message. I would

worry that the cause might be something other than the patches - though I do not

know. How is your husband doing now?

0.025 patches don't put out a lot of estradiol. A patch regime that has been

used to treat men in small clinical trials has is to apply six 0.10 all at once

on a single day, and to renew this weekly. I'm pretty sure the published studies

never indicated that any of these men experienced the symptoms you describe. I

myself have used the patches according to this regime, and sometimes in my

experimentation with other regimes, have inadvertently caused my serum estradiol

to test at much higher levels than the six patches/seven days regime would cause

during the first couple of days after the patches were applied.

If he is using Vivelle Dot patches - my experience with the 0.10 version of this

brand was that output of estradiol drops off very sharply after a couple of

days. Climara brand patches maintain levels higher for a longer period.

Why was he using the patch? Especially at such an extremely low, low dosage?

Clausen

> My husband started the Vivelle 0.025 on June 21. I did not realize completely

what was going on until tonight. He has some confusion (enough to tell me he

doesn't know what's happening to him), walking all around the house not

remembering what he is or was doing....quite often, losing parts of his day,

thinking something happened today that happened a couple days ago and sleeping

around 18 hours or more each day since the morning after putting the Vivelle

patch on (The sleeping started next morning after patch and the confusion

started today). Is this a Doctor phone call come Tuesday when they open? He

started Finesteride & Casodex last month.

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