Re: Update on E [1 Attachment]

[Guest guest]

Best wishes and I hope you can tap into the best of these treatments.

I'm right behind you in support and in progression, though we might not have such a choice yet in the UK

Update on E [1 Attachment]

My blood test from yesterday confirm what I suspected, my PSA isincreasing rapidly. It jumped from 81 on Dec 6th to 142 yesterday.I have been through virtually every rendition of hormone blockade, see attached.Due to the increase from October to December we had already began our(My Oncologist, my wife and myself) attempt to gain access to one ofthree options; XL 184, Abiraterone or Provenge. These are listed inorder of our preference.- XL 184; I am not eligible for the current trial as it requires organinvolvement. There is a new trial that is to open at any time thatremoves this requirement but waiting is not really an option.- Abiraterone; the good news is more and more sites are being added toOpen Label Phase III Trial. The bad news is none are available in themidwest. All of my paperwork has been sent to a location in LosAngels, not we wait and see.- Provenge; because this is not going to focus on reducing my PSA(according to what I have read) we are pursuing as a secondary option.A letter of medical necessity was sent to UnitedHealthcare inmid-December, they ahve 30 days to reply.Except for the jump in PSA I am otherwise doing fine. I continue towork full time and am looking for to my 48th birthday later this monthand my six year PCa anniversary in mid-February.Peace be with you all. I'll update you once we decide when and wherewe are off to for the next step in this crazy journey!-- Emersonwww.flhw.orgEvery 2.25 minutes a man is diagnosed with prostate cancer.Every 19 minutes a man, dies from the disease.

[Guest guest]

Emerson wrote:

> My blood test from yesterday confirm what I suspected, my PSA

> is increasing rapidly. It jumped from 81 on Dec 6th to 142

> yesterday.

>

> I have been through virtually every rendition of hormone

> blockade, see attached.

....

,

I am terribly sorry to hear this news.

I looked at your attachment and it appears to me that you've

tried damn near everything, but there are still a few treatments

I've heard of that weren't on your list. See:

http://www.hrpca.org/proventreatments.htm

I'm not qualified to say whether any of them even make sense for

you but you might want to investigate. A friend of mine

underwent Revlimid + Leukine and got a few months of benefit from

it.

Your decision to push your insurer on Provenge sounds like an

excellent idea. Even if the other possibilities come through for

you, you may eventually want or need Provenge in the future.

You said that Abiraterone is available, but not in the midwest.

I suggest that when you talk to the people in California, you ask

them about getting monitoring and followup care in your own home

town. People running a clinical trial will presumably want to

talk to you and give you a physical exam in person before

admitting you to the trial, but if the follow up care is standard

stuff - take certain pills, get certain blood tests, report the

results to the clinical trial site, they may be willing to allow

your local oncologist to do that part, or to do most of it. I've

heard of that being done. The cost to the trial sponsor may not

be any higher.

I wish you the best of luck.

Alan