Re: breastfeeding and blockers

[Guest guest]

" B " wrote on Wed, 29 Mar 2000 18:19:39 -0600

>I'm not sure what the word

>is one tapazole and nursing? Anybody?

Dr Arem says (on page 262, " The Thyroid solution " ):

" " Antithyroid medications are excreted in the milk, with PTU apparently

present in lower amounts than metimazole. Nevertheless, research has shown

that methimazole at a dose of 20 milligrams or less a day is safe for

newborns " "

On page 261:

" " If you were taking methimazole (tapazole) before becoming pregnant, your

doctor might switch you to propylthiouracil (PTU) because of the possibility

of a rare congenital abnormality of the scalp called aplasia cutis. There is

considerable doubt about this complication occurring as a result of

Tapazole, but many doctors feel it is safer to use PTU during pregnancy. As

the pregnancy progresses, the activity of Graves' disease slows down,and the

dose of antithyroid medication must be gradually reduced so that thyroid

hormone levels remain on the high side throughout the pregnancy. PTU crosses

the placenta and can cause hypothyroidism in the fetus if the dose is too

high " "

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