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See my latest post; in addition to the above, I checked with the University

of California at San Francisco, California Pacific Medical Center, at San

Francisco,

Stanford University, and just for kicks, the University of Michigan at Ann

Arbor,

Michigan.

n Rojas (again)

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Nope: I have it on reliable authority, that if each parent is to be a

carrier, each of

theirs needs to be one, too--which is why it shows up so often in

grandchildren.

It goes like this:

one parent who is carrier plus one parent who is not = no cf, and no cf

carriers

two parents who are carriers:

odds for each pregnancy, EACH then become: one for cf

one for

neither cf nor carrier

TWO

FOR CARRIERS

I site as my sources: Stanford University CF Center, Palo Alto Ca

California Pacific CF Center, San Francisco,

Ca

University of California at San Francisco CF

Center, S.F., Ca

Universotu of Michigan CF Center, Ann Arbor,

Michigan

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hi, my name is april, new to this list. i am a carrier, so is curt, we have

two children, Chad and Terrance,.. Chad HAS CF, but Terry doesnt even carry

it. Had bloodwork on him and sweat tests, nothing, so they must be wrong.

Sorry.

April D. mom of

Chad 9pwcf and

Terry 7nocf

ope: I have it on reliable authority, that if each parent is to be a

> carrier, each of

> theirs needs to be one, too--which is why it shows up so often in

> grandchildren.

> It goes like this:

>

> one parent who is carrier plus one parent who is not = no cf, and no cf

> carriers

> two parents who are carriers:

> odds for each pregnancy, EACH then become: one for cf

> one

for

> neither cf nor carrier

> TWO

> FOR CARRIERS

>

> I site as my sources: Stanford University CF Center, Palo Alto Ca

> California Pacific CF Center, San

Francisco,

> Ca

> University of California at San Francisco

CF

> Center, S.F., Ca

> Universotu of Michigan CF Center, Ann

Arbor,

> Michigan

>

>

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April,

I also have two children, Liam who is 6 wocf and not even a carrier and

Eilish who is 3 wcf. So luckily for us this is a good thing.

Re: geneticsresponse/reply

> hi, my name is april, new to this list. i am a carrier, so is curt, we

have

> two children, Chad and Terrance,.. Chad HAS CF, but Terry doesnt even

carry

> it. Had bloodwork on him and sweat tests, nothing, so they must be wrong.

> Sorry.

>

> April D. mom of

> Chad 9pwcf and

> Terry 7nocf

>

>

> ope: I have it on reliable authority, that if each parent is to be a

> > carrier, each of

> > theirs needs to be one, too--which is why it shows up so often in

> > grandchildren.

> > It goes like this:

> >

> > one parent who is carrier plus one parent who is not = no cf, and no cf

> > carriers

> > two parents who are carriers:

> > odds for each pregnancy, EACH then become: one for cf

> > one

> for

> > neither cf nor carrier

> >

TWO

> > FOR CARRIERS

> >

> > I site as my sources: Stanford University CF Center, Palo Alto Ca

> > California Pacific CF Center, San

> Francisco,

> > Ca

> > University of California at San

Francisco

> CF

> > Center, S.F., Ca

> > Universotu of Michigan CF Center, Ann

> Arbor,

> > Michigan

> >

> >

>

>

>

> ***********************

> This is a secular list.

> ***********************

>

>

> PLEASE do not post religious emails to the list.

>

>

> --------------------------------------------------

>

>

> The opinions and information exchanged on this list should

> IN NO WAY

> be construed as medical advice.

>

> PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR

TREATMENTS.

>

> --------------------------------------------------

>

>

> Our webpage is at http://www.eohio.net/malbright/cfparents.htm

>

> _________________________________________________

> Post message: cfparentsegroups

> Subscribe: cfparents-subscribeegroups

> Unsubscribe: cfparents-unsubscribeegroups

> List owner: cfparents-owneregroups

> _________________________________________________

>

> WE HAVE A CHAT PAGE!!!

> /chat/cfparents

> _________________________________________________

>

>

>

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Why would they be wrong? 25% chance of no cf/no carrier status. Welcome to the

list.

Lou

April Dewell wrote:

> hi, my name is april, new to this list. i am a carrier, so is curt, we have

> two children, Chad and Terrance,.. Chad HAS CF, but Terry doesnt even carry

> it. Had bloodwork on him and sweat tests, nothing, so they must be wrong.

> Sorry.

>

> April D. mom of

> Chad 9pwcf and

> Terry 7nocf

>

> ope: I have it on reliable authority, that if each parent is to be a

> > carrier, each of

> > theirs needs to be one, too--which is why it shows up so often in

> > grandchildren.

> > It goes like this:

> >

> > one parent who is carrier plus one parent who is not = no cf, and no cf

> > carriers

> > two parents who are carriers:

> > odds for each pregnancy, EACH then become: one for cf

> > one

> for

> > neither cf nor carrier

> > TWO

> > FOR CARRIERS

> >

> > I site as my sources: Stanford University CF Center, Palo Alto Ca

> > California Pacific CF Center, San

> Francisco,

> > Ca

> > University of California at San Francisco

> CF

> > Center, S.F., Ca

> > Universotu of Michigan CF Center, Ann

> Arbor,

> > Michigan

> >

> >

>

> ***********************

> This is a secular list.

> ***********************

>

> PLEASE do not post religious emails to the list.

>

> --------------------------------------------------

>

> The opinions and information exchanged on this list should

> IN NO WAY

> be construed as medical advice.

>

> PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR TREATMENTS.

>

> --------------------------------------------------

>

> Our webpage is at http://www.eohio.net/malbright/cfparents.htm

>

> _________________________________________________

> Post message: cfparentsegroups

> Subscribe: cfparents-subscribeegroups

> Unsubscribe: cfparents-unsubscribeegroups

> List owner: cfparents-owneregroups

> _________________________________________________

>

> WE HAVE A CHAT PAGE!!!

> /chat/cfparents

> _________________________________________________

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Hi again, sorry, long day, i read it wrong i think the first time. the first

time i scanned it it looked like the message meant if both parents were

carriers, then so must the child be one too, but thats not so as we know.

April D mom of

Chad 9pwcf and

Terry 7 nocf

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The Cystic Fibrosis Foundation website

( http://www.cff.org/facts.htm ) states the following:

"

An individual must inherit a defective copy of the CF gene — one from

each parent — to have cystic fibrosis. Each time two carriers

conceive a child, there is a 25 percent chance that the child will

have CF; a 50 percent chance that the child will be a carrier; and a

25 percent chance that the child will be a non-carrier.

"

So carrier status can be passed from a single parent who is a

carrier, and it does take two carriers (with one or more defective cf

gene) to produce a child with cf, and two carriers CAN produce a

child who does not carry any copies of the defective gene.

I did enjoy the shoe analogy!

~

mommy of 3, 1 wcf

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This is correct with respect to TWO carrier parents. However, one carrier

parent DOES create a 50/50 chance that each child CARRIES the CF gene. I

challenge you to find a source that says when only one parent is a carrier

(like each and every one of us, by the way) that NO child will carry the gene.

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Perhaps the difference betweene allele (I never spell this right) and gene is

what

is what matters here; it takes one cf person and one carrier to produce 50/50

liklihood of a cf child at that rate and ALL carriers; I know, because those

are

my experiences, and our whole family has been genetically analyzed to death.

No, you don't need me to get the situation clear; read Orenstein; call the

CFF;

talk with your cf geneticist. I am not into challenges; this all came up in

response

to a cf mother's question. If you can provide or lead to better information,

please do so, with my blessing,

n Rojas

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Is anybody arguing this point? It is bby default that a CF person is a carrier.

50% will have Cf and the other 50% will ONLY carry the gene. Hopefully,

everybody understands what n is saying.

Re: geneticsresponse/reply

Perhaps the difference betweene allele (I never spell this right) and gene is

what

is what matters here; it takes one cf person and one carrier to produce 50/50

liklihood of a cf child at that rate and ALL carriers; I know, because those

are

my experiences, and our whole family has been genetically analyzed to death.

No, you don't need me to get the situation clear; read Orenstein; call the

CFF;

talk with your cf geneticist. I am not into challenges; this all came up in

response

to a cf mother's question. If you can provide or lead to better information,

please do so, with my blessing,

n Rojas

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