Re: Once again, how does HC work in the body?

[Guest guest]

> They were never really unstable in the first place. Let's say my temps are

stable at 7.5 mg HC. Just an example. How can adrenals rest properly when only

taking 7.5 mg HC? And taking higher doses of T3 cannot be " safe " when taking

such a low amount of HC? Again, just an example.

It depends on the state of the " feedback loop " and what was wrong with

it in the first place.

Using some engineering terms that deal with control loops, also trying

to explain what I mean by them

If the problem was that the maximum rate of production was too low but

that it was accurately asked for then a wide range of additional

hormone levels would all have the same effect as your own production

would make up the lack and the supplement would make up the lack in

your own production.

If on the other hand the " set point " (how much it was trying to

regulate to) or the " loop gain " (how much it added or reduced as a

result of the wrong amount being there) were wrong you would have to

fully supplement to shut down your own production and add still more

in order to get enough in your system and keep it there.

It sounds to me as though your body is trying to regulate cortisol but

that it can't produce enough in stressful circumstances and first

thing in the morning, in this case a change from 20 to 30 may have no

effect, your own just changes in sympathy.

Stress dosing by adding an extra 2.5 or 5 will make a different by

providing temporary additional levels.

How were you for the additional T3?

Nick

[Guest guest]

So you would say that I should try to go down to 20 mg HC daily? I am currently trying 27.5 mg again. To see if I get a headache if I do so.What about T3 and HC? More HC makes a person tolerate more T3, yes?

> They were never really unstable in the first place. Let's say my temps are stable at 7.5 mg HC. Just an example. How can adrenals rest properly when only taking 7.5 mg HC? And taking higher doses of T3 cannot be "safe" when taking such a low amount of HC? Again, just an example.

It depends on the state of the "feedback loop" and what was wrong with

it in the first place.

Using some engineering terms that deal with control loops, also trying

to explain what I mean by them

If the problem was that the maximum rate of production was too low but

that it was accurately asked for then a wide range of additional

hormone levels would all have the same effect as your own production

would make up the lack and the supplement would make up the lack in

your own production.

If on the other hand the "set point" (how much it was trying to

regulate to) or the "loop gain" (how much it added or reduced as a

result of the wrong amount being there) were wrong you would have to

fully supplement to shut down your own production and add still more

in order to get enough in your system and keep it there.

It sounds to me as though your body is trying to regulate cortisol but

that it can't produce enough in stressful circumstances and first

thing in the morning, in this case a change from 20 to 30 may have no

effect, your own just changes in sympathy.

Stress dosing by adding an extra 2.5 or 5 will make a different by

providing temporary additional levels.

How were you for the additional T3?

Nick

[Guest guest]

>So you would say that I should try to go down to 20 mg HC daily? I am currently

trying 27.5 mg again. To see if I get a headache if I do so.

I would leave the HC alone until you had a decent daily dose of T3,

change one thing at a time, As T4 levels are sinking you will be able

to, and need to, increase T3. Only after you have got to a stable dose

would I start to see what happens weaning HC

>

>What about T3 and HC? More HC makes a person tolerate more T3, yes?

Only if you are deficient in it. It's not a case of more is better,

it's a case of enough is good enough.

Nick

[Guest guest]

I know I am on enough HC when I have no arrhythmia.

I just slowly increased till I had no problem with heartbeat.

It will happen occasionally but usually only if I miss a dose of HC.

Magnesium and potassium have also helped.

Also it is probably good to look at how big a person is and how much they weigh

in terms of dosage.I'm 5'1 " so I don't think my dose would

likely be the same as that of a 6' man.

Chantal

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> Been trying to get this but I still haven't fully:

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> When I start taking HC, and go up to a dose of let's say 20-25 mg daily.. What

happens to my adrenal glands? Well, I know that ACTH is going down.

> BUT _is the GOAL_ to shut down ACTH completely, to give the adrenals the

Proper rest they need? Or should we never, ever shut down ACTH completely, in

fear of loosing the adrenal glands own production of cortisol forever?

> While we're on HC, we cannot test it. The blood, urine and saliva sample

results get skewed. But testing serum ACTH should work, right? Where should ACTH

be in serum while taking an optimal dose of HC?

> I am currently taking 27.5 mg HC daily. I went up 2 days ago. My specialist

tells me that I should take more to tolerate T3 better, HC will be the " Backup "

securing T3, in her words.

> I have no idea what so ever how much HC I need. My temps are stable. They were

stable when taking 20 mg HC too. So what should I do, take more HC to make

taking T3 safer for me? (My specialist is worried about the arrhythmias I've

been getting since starting with T3) Or take less HC until my temps become

unstable? - They were never really unstable in the first place. Let's say my

temps are stable at 7.5 mg HC. Just an example. How can adrenals rest properly

when only taking 7.5 mg HC? And taking higher doses of T3 cannot be " safe " when

taking such a low amount of HC? Again, just an example.

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