Guest guest Posted January 22, 2010 Report Share Posted January 22, 2010 I'm not the expert, but it may be that you were on slow release, which is weaker, which would indicate you need to start at a lower dose. I was taking 3 grains Thyroid-S and started on 28.5 mcg of T3. I increased by 6.25 mcg per week until I got up to 100 mcg. I have adrenal problems but I never had an issue with T3 at this rate. (I do now because I'm at the 12 week mark - so I'm sure RT3 has now cleared). Maybe start with 12.5 twice a day, and increase 6.25 each week? > > On Sunday, I started Cytomel (started with generic -- switched to brand name on Tuesday) after being on an T3/T4 slow release comb. equivalent to 2 grains of Armour. So, I am 5 days into T3 only. According to the dosing chart, I should start with 25mcg and spread it throughout the day. I have tried doing this, but my chest has been very tight and my heart seems to race at times. My pulse increases to higher than is comfortable for me -- when mine gets into the 80 bpm range -- that is when my heart feels funny and fluttery. I keep dropping my dose back and spreading it out -- am down to 18.75 mcg per day (6.25 mcg per dose) and still having these sypmtoms. Am confused because don't know if I have just started with too high a dose of T3 or if I should consider some other reason for intolerance given that 25 mcg should seem to be a reasonable starting dose. Am wondering if I should get a Cytomel prescription for 5 mcg/ 5 times per > day? The heart stuff scares me. I am in very good physical shape as I run 5-6 miles 6 days a week. Any thoughts? My original FT3/RT3 ratio was 10. When my pulse is up, my temps do seem to go up also. > > Any help is appreciated. > > Thanks, > Beth > > Thanks, > Beth > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 22, 2010 Report Share Posted January 22, 2010 Thank you -- that makes sense and is what I was wondering. Since Sunday, I have seen more 98.4 and 98.6 temps than ever before which makes me think I am headed in the right direction. The increased pulse and chest pain is what scared me. I just talked with my doc and he is going to call in a 5 mcg/ prescription with up to 5 pills a day. You are correct that the t3/t4 I was on was compounded slow release which does absorb less -- I hadn't thought about that -- that would explain why 25 mcg was too high to begin with. It helps consulting with others on this and I appreciate your thoughts. Thanks, bs To: RT3_T3 Sent: Fri, January 22, 2010 11:09:59 AMSubject: Re: Confused about T3 dose and need advice I'm not the expert, but it may be that you were on slow release, which is weaker, which would indicate you need to start at a lower dose. I was taking 3 grains Thyroid-S and started on 28.5 mcg of T3. I increased by 6.25 mcg per week until I got up to 100 mcg. I have adrenal problems but I never had an issue with T3 at this rate. (I do now because I'm at the 12 week mark - so I'm sure RT3 has now cleared).Maybe start with 12.5 twice a day, and increase 6.25 each week?>> On Sunday, I started Cytomel (started with generic -- switched to brand name on Tuesday) after being on an T3/T4 slow release comb. equivalent to 2 grains of Armour. So, I am 5 days into T3 only. According to the dosing chart, I should start with 25mcg and spread it throughout the day. I have tried doing this, but my chest has been very tight and my heart seems to race at times. My pulse increases to higher than is comfortable for me -- when mine gets into the 80 bpm range -- that is when my heart feels funny and fluttery. I keep dropping my dose back and spreading it out -- am down to 18.75 mcg per day (6.25 mcg per dose) and still having these sypmtoms. Am confused because don't know if I have just started with too high a dose of T3 or if I should consider some other reason for intolerance given that 25 mcg should seem to be a reasonable starting dose. Am wondering if I should get a Cytomel prescription for 5 mcg/ 5 times per> day? The heart stuff scares me. I am in very good physical shape as I run 5-6 miles 6 days a week. Any thoughts? My original FT3/RT3 ratio was 10. When my pulse is up, my temps do seem to go up also. > > Any help is appreciated.> > Thanks,> Beth> > Thanks,> Beth> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 22, 2010 Report Share Posted January 22, 2010 > >Any help is appreciated. How are adrenals and ferritin??? How much your body is used to depends on how good the compounding was in the T4/T3 mix. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 22, 2010 Report Share Posted January 22, 2010 Nick, can you get hypo sxs from too much HC, btw? > > > > >Any help is appreciated. > > How are adrenals and ferritin??? > > How much your body is used to depends on how good the compounding was > in the T4/T3 mix. > > Nick > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 23, 2010 Report Share Posted January 23, 2010 > >Nick, can you get hypo sxs from too much HC, btw? Val says that symptoms of too much HC are VERY similar to those of too little. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 23, 2010 Report Share Posted January 23, 2010 >Any help is appreciated. Really not sure how to proceed with dosage. Afraid to stop all together, but afraid to take more with increased bpm. Sometimes (with the emphasis on sometimes) low T3 can cause adrenals to try and make up for it. They fail to put our cortisol and end up putting out adrenaline instead. This gives rise to a fast pulse and sometimes a pounding too. I have seen cases where more T3 corrects this and actually drops pulse as a result. Does this feel plausible for you?? Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 23, 2010 Report Share Posted January 23, 2010 Nick, I wondered the same thing, so last night at 10pm when bpm was up and I hadn't had a dose in 8 hrs (and a small dose at that) I wondered if was actually low T3. So, I took another 5 mcg at 10:15and bpm got even higher and heart pounded harder. It was scary. This am -- I've started out with 2.5 mcg and will see how that does (that was an hour ago and so far so good -- but not sure this is a high enough dose to get my temps up)-- maybe I could try this low dose, but more frequently. If that doesn't help -- should I try some Isocort? and if so, how should I dose it? However, if I had low cortisol or low adrenals, wouldn't I be fatigued and low energy? I sleep well, feel good re: energy which makes me think it is not adrenals. Before starting Armour 2 years ago I was EXHAUSTED and did not get restful sleep. Since starting thyroid Tx have felt 100% better. Am almost tempted to start back with T3/T4 combo given I had gradually improving temps and bpm was more stable. Thanks with help trying to figure out this puzzle. Beth To: RT3_T3 Sent: Sat, January 23, 2010 4:30:10 AMSubject: Re: Confused about T3 dose and need advice >Any help is appreciated. Really not sure how to proceed with dosage. Afraid to stop all together, but afraid to take more with increased bpm. Sometimes (with the emphasis on sometimes) low T3 can cause adrenalsto try and make up for it. They fail to put our cortisol and end upputting out adrenaline instead.This gives rise to a fast pulse and sometimes a pounding too.I have seen cases where more T3 corrects this and actually drops pulseas a result.Does this feel plausible for you??Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 23, 2010 Report Share Posted January 23, 2010 Nick, Me again. Sorry to bother you again, but I am so baffled by my reaction to low doses of Cytomel. Ok, so it is now 9:30 -- two hours after taking 2.5 mcg Cytomel (brand name). My chest is tight and I feel a little labored when I breathe. My pulse is almost 80 bpm and my temp. is up to 98.3 (which is good for me). My waking temp was 97.1 and bpm was 62. I can't really go any lower in dose than 2.5 mcg. Last dose before this morning was 5mcg last night at 10:30. I did have 2-3 glasses of wine last night -- could that have any effect? Although that is the only night I have had wine this week and tightness has been there all week. So confused. Thanks, Beth To: RT3_T3 Sent: Sat, January 23, 2010 8:05:23 AMSubject: Re: Confused about T3 dose and need advice Nick, I wondered the same thing, so last night at 10pm when bpm was up and I hadn't had a dose in 8 hrs (and a small dose at that) I wondered if was actually low T3. So, I took another 5 mcg at 10:15and bpm got even higher and heart pounded harder. It was scary. This am -- I've started out with 2.5 mcg and will see how that does (that was an hour ago and so far so good -- but not sure this is a high enough dose to get my temps up)-- maybe I could try this low dose, but more frequently. If that doesn't help -- should I try some Isocort? and if so, how should I dose it? However, if I had low cortisol or low adrenals, wouldn't I be fatigued and low energy? I sleep well, feel good re: energy which makes me think it is not adrenals. Before starting Armour 2 years ago I was EXHAUSTED and did not get restful sleep. Since starting thyroid Tx have felt 100% better. Am almost tempted to start back with T3/T4 combo given I had gradually improving temps and bpm was more stable. Thanks with help trying to figure out this puzzle. Beth From: Nick Foot <lists@oakfield- icelandics. co.uk>To: RT3_T3yahoogroups (DOT) comSent: Sat, January 23, 2010 4:30:10 AMSubject: Re: Confused about T3 dose and need advice >Any help is appreciated. Really not sure how to proceed with dosage. Afraid to stop all together, but afraid to take more with increased bpm. Sometimes (with the emphasis on sometimes) low T3 can cause adrenalsto try and make up for it. They fail to put our cortisol and end upputting out adrenaline instead.This gives rise to a fast pulse and sometimes a pounding too.I have seen cases where more T3 corrects this and actually drops pulseas a result.Does this feel plausible for you??Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 >Me again. Sorry to bother you again, but I am so baffled by my reaction to low doses of Cytomel. Ok, so it is now 9:30 -- two hours after taking 2.5 mcg Cytomel (brand name). My chest is tight and I feel a little labored when I breathe. My pulse is almost 80 bpm and my temp. is up to 98.3 (which is good for me). My waking temp was 97.1 and bpm was 62. I can't really go any lower in dose than 2.5 mcg A pulse of 80 and temp of 98.3 is still hypo, just less hypo than you are used to. the Chest issue may be hypo still, as the hypo clears in different parts of you it is possible that it feels strange. It could also be adrenal symptoms brought on by the extra T3 using more cortisol I wonder what would happen if you took small doses of t3 more often, get your body used to it without stressing adrenals. The variation in level is what may be causing strange things. Something like 2.5 every 4 hours to start with and then bring it closer together over a week or so until you are taking them every 2 hours. Nick -- for more information on RT3 and Thyroid Resistance go to www.thyroid-rt3.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 >I wondered the same thing, so last night at 10pm when bpm was up and I hadn't had a dose in 8 hrs (and a small dose at that) I wondered if was actually low T3. So, I took another 5 mcg at 10:15 >and bpm got even higher and heart pounded harder. It was scary. I am thinking that the T3 is taking adrenal levels down and causing adrenaline to be produced instead of cortisol Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 Nick, So funny, I didn't check my e-mails until now -- but I was thinking exactly the same thing and have been doing that today -- have had 3 doses of 2.5 four hours apart and so far so good. There was some tightness again in right side of my chest this morning, but I took ibuprofen and that seemed to help. Right side of chest pain is more pulmonary than heart related I think. How long does it usually take for T4 to clear? I wonder if I will be able to tolerate more T3 when T4 clears. Just curious when to anticipate this? It really helps to have someone to consult about all this and particularly helpful when my gut tells me which way to go and then you confirm it with your advice. I really do appreciate your help. Thanks, Beth To: RT3_T3 Sent: Sun, January 24, 2010 5:53:49 AMSubject: Re: Confused about T3 dose and need advice >Me again. Sorry to bother you again, but I am so baffled by my reaction to low doses of Cytomel. Ok, so it is now 9:30 -- two hours after taking 2.5 mcg Cytomel (brand name). My chest is tight and I feel a little labored when I breathe. My pulse is almost 80 bpm and my temp. is up to 98.3 (which is good for me). My waking temp was 97.1 and bpm was 62. I can't really go any lower in dose than 2.5 mcgA pulse of 80 and temp of 98.3 is still hypo, just less hypo than youare used to.the Chest issue may be hypo still, as the hypo clears in differentparts of you it is possible that it feels strange.It could also be adrenal symptoms brought on by the extra T3 usingmore cortisolI wonder what would happen if you took small doses of t3 more often,get your body used to it without stressing adrenals. The variation inlevel is what may be causing strange things.Something like 2.5 every 4 hours to start with and then bring itcloser together over a week or so until you are taking them every 2hours.Nick-- for more information on RT3 and Thyroid Resistance go to www.thyroid- rt3.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 >It really helps to have someone to consult about all this and particularly helpful when my gut tells me which way to go and then you confirm it with your advice. I really do appreciate your help. Glad it's helping, Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 25, 2010 Report Share Posted January 25, 2010 Nick, So, what should I do if this is the case? What about the Dessicated Adrenal Gland supplement (bovine) that Venezia was talking about. Should I supplement with something like this to help adrenals or do I need something to supplement cortisol? I have been spacing Cytomel 2.5 mcg doses every 4 hours and this is working much better. To: RT3_T3 Sent: Sun, January 24, 2010 5:55:18 AMSubject: Re: Confused about T3 dose and need advice >I wondered the same thing, so last night at 10pm when bpm was up and I hadn't had a dose in 8 hrs (and a small dose at that) I wondered if was actually low T3. So, I took another 5 mcg at 10:15>and bpm got even higher and heart pounded harder. It was scary.I am thinking that the T3 is taking adrenal levels down and causingadrenaline to be produced instead of cortisolNick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 26, 2010 Report Share Posted January 26, 2010 > >So, what should I do if this is the case? What about the Dessicated Adrenal Gland supplement (bovine) that Venezia was talking about. Should I supplement with something like this to help adrenals or do I need something to supplement cortisol? I have been spacing Cytomel 2.5 mcg doses every 4 hours and this is working much better. Glad that's working better Isocort is the usual over the counter " help the adrenals a bit " option. Val can help you more about dosing than I can You might want to take an adrenal saliva test at this T3 dosing and see how they look. Nick Quote Link to comment Share on other sites More sharing options...
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