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Re: Nicolson on mycoplasma species, cp, and antibiotics

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Hello, a, As one who has the M. Pneumoniea, this is certainly interesting.

I am on the minicin (perhaps for two other micoplasms) and the clindy IV

one/month and every six months the five day IV regime. If this is so difficult

to get rid of, I wonder the only one clindy IV/mo. is enough since I don't get

the Zithromax. I do know RTC has suggested I might need the clindys more

than I am getting. I also know I am doing remarkably well right now. Am in a

flare but the hands and feet only barely ache, NO PAIN. But if the little

buggers are that difficult to treat and just hide, biding their evil time, then

I would rather blast them harder. Food for thought here. Thanks so much for

sharing, a, :>))

a Carnes wrote:

> From: a Carnes <paulajeanne@...>

>

> Hi,

>

> This was sent to me from Garth Nicholson (thank you Garth) and I thought

> it would be of interest to others.

>

> I do have one other question, Garth. Would you suggest two different

> antibiotics at once for the treatment of M-Pneumoniae?

>

> Best,

> Rona

>

> <<From: " Prof. Garth L. Nicolson "

>

> In response to your email to cpar:

>

> 1. With M-Pneumoniae, what would you expect to be the duration of time to

>

> take Zithromax at 500 mg. qd?

>

> WE RECOMMEND ZITHROMAX BECAUSE MYCOPLASMA PNEUMONIAE IS RESPONSIVE TO THIS

> ANTIBIOTIC. YOU CAN USE IT AT 250 OR 500 MG/DAY, DEPENDING ON YOUR

> CLINICAL RESPONSE.

>

> 2. Is it overly optimistic to expect to be fully rid of the mycoplasma

>

> within a year or two or *ever*? After reading all of a's posts about

>

> her situation, I am wondering if I am looking at a lifetime on Zithromax.

>

> THESE INFECTIONS ARE EXTREMELY DIFFICULT TO COMPLETELY IRRADICATE. MOST

> PATIENTS WILL EVENTUALLY OVERCOME THE INFECTION, BUT THERE MAY BE SOME

> RESIDUAL MICROORGANISM THAT REMAINS IN A PERSISTANCE PAHSE OR INACTIVE

> PHASE INDEFINITELY.

>

> 3. Is there another drug to consider adding in (note: I can't take Doxy)?

>

> THE FALL-BACK WOULD BE SPARFLOXACIN OR CIPROFLOXACIN OR CLINDAYMCIN.

>

> 4. Do you do c-pneumoniae testing in your lab?

>

> YES WE DO, ALONG WITH 5 OTHER MYCOPLASMA SPECIES AND CHLAMYDIA SPECIES, ETC.

>

> 5. In your experience, do you usually see M-P along with C-Pneumoniae? As

>

> in, should one automatically go ahead and get tested if one has the former?

>

> Blood or sputum?

>

> OFTEN PATIENTS HAVE BOTH MYCOPLASMAL AND CHLAMYDIAL INFECTIONS, BUT MANY

> HAVE EITHER ONE ALONE.

>

> YOU CAN POST THIS TO CPAR (I have taken the liberty to post this here as

> Dr. Nicolson has always said I may post his comments to any who need help.

> a Carnes)

>

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wrote:

If this is so difficult

> to get rid of, I wonder the only one clindy IV/mo. is enough since I don't

get

> the Zithromax. I do know RTC has suggested I might need the clindys

more

> than I am getting. I also know I am doing remarkably well right now. Am

in a

> flare but the hands and feet only barely ache, NO PAIN. But if the little

> buggers are that difficult to treat and just hide, biding their evil time,

then

> I would rather blast them harder

, I am sort of in the same boat. I will see Dr. Speight in Charlotte

in two weeks. I have mycoplasma incognitus and the Zithromax is not getting

rid of it. It controls it but if I even drop the dose I relapse. I will

post to the list as soon as I talk with him.

a Carnes

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