Nicolson on mycoplasma species, cp, and antibiotics

[Guest guest]

Hi,

This was sent to me from Garth Nicholson (thank you Garth) and I thought

it would be of interest to others.

I do have one other question, Garth. Would you suggest two different

antibiotics at once for the treatment of M-Pneumoniae?

Best,

Rona

<<From: " Prof. Garth L. Nicolson "

In response to your email to cpar:

1. With M-Pneumoniae, what would you expect to be the duration of time to

take Zithromax at 500 mg. qd?

WE RECOMMEND ZITHROMAX BECAUSE MYCOPLASMA PNEUMONIAE IS RESPONSIVE TO THIS

ANTIBIOTIC. YOU CAN USE IT AT 250 OR 500 MG/DAY, DEPENDING ON YOUR

CLINICAL RESPONSE.

2. Is it overly optimistic to expect to be fully rid of the mycoplasma

within a year or two or *ever*? After reading all of a's posts about

her situation, I am wondering if I am looking at a lifetime on Zithromax.

THESE INFECTIONS ARE EXTREMELY DIFFICULT TO COMPLETELY IRRADICATE. MOST

PATIENTS WILL EVENTUALLY OVERCOME THE INFECTION, BUT THERE MAY BE SOME

RESIDUAL MICROORGANISM THAT REMAINS IN A PERSISTANCE PAHSE OR INACTIVE

PHASE INDEFINITELY.

3. Is there another drug to consider adding in (note: I can't take Doxy)?

THE FALL-BACK WOULD BE SPARFLOXACIN OR CIPROFLOXACIN OR CLINDAYMCIN.

4. Do you do c-pneumoniae testing in your lab?

YES WE DO, ALONG WITH 5 OTHER MYCOPLASMA SPECIES AND CHLAMYDIA SPECIES, ETC.

5. In your experience, do you usually see M-P along with C-Pneumoniae? As

in, should one automatically go ahead and get tested if one has the former?

Blood or sputum?

OFTEN PATIENTS HAVE BOTH MYCOPLASMAL AND CHLAMYDIAL INFECTIONS, BUT MANY

HAVE EITHER ONE ALONE.

YOU CAN POST THIS TO CPAR (I have taken the liberty to post this here as

Dr. Nicolson has always said I may post his comments to any who need help.

a Carnes)