Re: cea and intestinal permeability...

[Guest guest]

Hi Seth,

In Feb. I posted a document Intestinal Permeability and recommended being

tested. I am glad that someone finally

confirmed the relationship between Leaky Gut Syndrome and rosacea. Since I

joined the group a year ago I have been

trying to explain that I cured my skin problems by improving digestion, speeding

transit time and ensuring complete

elimination of waste. So many different symptoms occur when the bodies toxins

are reabsorbed from the colon into the

blood. All the factors involved make it a very complicated and confusing issue

along with effecting different

subjects at varied degrees. This makes the cause difficult to pin point. Most

often only the symptoms

are treated as real cause is over looked and gradually worsens.

Most of all I would like to say that you did an excellent job presenting the

information to the group and thank

you!

Take

care,

Mark

Seth 1 wrote:

> Hello group.

>

> A few months ago, I posted a message discussing the possible link between

> rosacea and " leaky gut " syndrome. I was wondering if anyone had been giving

> this any further thought and also I thought I'd let you know about a recent

> development.

>

> Basically, to recap " leaky gut " syndrome (or more formally intestinal

> hyperpermeability) is a condition where the digestive tract becomes

> excessively porous and as a result undesirable material (such as partially

> digested food, bacteria, toxins etc.) are able to escape into the blood

> stream. This may sound gruesome, but in fact the condition is considered to

> be relatively common and it may not cause any noticeable symptoms.

>

> As I mentioned in my previous post, I believe there are number of reasons

> that support the idea that " leaky gut " syndrome might play a role in the

> pathogenesis of rosacea. (See the end of this email for a summary of these

> main reasons.)

>

> Fortunately, there is a relatively simple urine test to confirm the

> existence of this condition. I decided to ask my (new) doctor what she

> thought about this and also to ask her if I could take such a test.

> Unfortunately, she was not as open minded as my previous doctor – she

> insisted that rosacea was just a form of teenage acne and she refused to

> submit me for such a test. I was thoroughly disappointed, not least because

> it was quite obvious that she really didn’t know very much about rosacea.

> I’m not trying to claim that I am a medical expert, but I have read a great

> deal of medical literature concerning this disease (as I’m sure many of you

> have) and many of the things she was saying were in direct conflict with

> this. Anyway, that was the end of that.

>

> However, about a month later I was surfing the net and I discovered a

> medical lab in the UK (where I live) that would perform such a test by mail

> order. (For those who are interested, they used the PEG 400 test, which

> uses a variety of different molecular sizes, not the lactulose/mannitol,

> which only uses two.) The only proviso was that they would only send the

> results to my doctor. After confirming with another doctor at my surgery,

> that it would be ok for him to receive my results, I underwent the test.

> About a week later the results came back and they showed that throughout the

> mid-range of molecular sizes, my intestinal permeability was well above the

> upper-limit of normal (by about twice the normal range). The doctor was

> quite surprised by the result. He gave me a blood test for common food

> allergies (which regularly causes increased permeability), but these were

> negative and he has made an appointment for me to see a gastroenterologist.

>

> Anyway, the web site address for the lab that performed this test is

> http://www.biolab.co.uk and the test costs £40. I’m sure there are similar

> labs in the US and elsewhere. I would be very interested to hear of any

> other rosacea sufferers who were motivated enough to undergo such a test. I

> would like to point out that I have never considered my self to have any

> sort of digestive disease.

> I look forward to any replies.

>

> Best regards,

> Seth

>

> P.S. I thought I would include a quick summary of the main reasons that

> support the association between intestinal permeability and rosacea.

>

> 1. There has been a long history of association between digestive

> disturbance and rosacea.

>

> 2. cea has long been linked to Irritable Bowel Disease (Crohn’s disease

> and Ulcerative Colitis). It is now a well-established fact that patients

> with these diseases have increased intestinal permeability and that the

> level of intestinal permeability correlates well with the severity of their

> disease.

>

> 3. Antibiotics are known to be effective in the treatment of many cases of

> rosacea and they are also known (in the short-term) to reduce intestinal

> permeability in many cases. Also the antibiotics that are effective in

> rosacea (for example, tetracycline and metronidazole) are also the most

> effective at reducing intestinal permeability as well as improving diseases

> such as Crohn’s (in the short term). (Please note that antibiotics are also

> believed to be an important cause of Leaky Gut Syndrome.)

>

> 4. cea patients often complain of food allergy. As mentioned, food

> allergy commonly causes increased intestinal permeability (as does any form

> of inflammation of the intestinal tract.)

>

> 5. cea patients often complain of autoimmune disorders (for example

> arthritis or Raynaud’s (intense coldness of fingers, toes, nose or even

> body)) and it has been shown that rosacea patients are more likely to test

> positively for ANA. This could well be explained by the body being exposed

> to a variety of allergens leaking into the blood stream from the intestines

> and that these send the immune system into overdrive.

>

> 6. As we all know, the bacterium that causes stomach ulcers H. Pylori has

> been tentatively linked to rosacea. It is well known that H. Pylori

> infection commonly increases gastric permeability.

>

> 7. cea has been linked to hypochlorhydria (reduced production of

> stomach acid). This can commonly lead to increased intestinal permeability

> by (a) not killing bacteria in the stomach and letting them progress through

> to the intestines and ( by only partially digesting proteins this food can

> cause “unfriendly bacteria” to thrive in the intestines. In both cases this

> intestinal dysbiosis can quickly irritate and inflame the intestinal wall

> and lead to increased permeability.

>

> 8. Many women have found that their rosacea either worsens or even begins

> following pregnancy. Apparently, during pregnancy intestinal permeability

> increases. Many women have also found that taking the birth control pill can

> worsen the rosacea symptoms. Apparently this too, can increase intestinal

> permeability. (Unfortunately I cannot remember where I read this.)

>

> 9. Many rosacea patients (on this group) apparently have problems with

> candida overgrowth. Again this is apparently a well-known cause of “Leaky

> Gut” syndrome.

>

> 10. cea sufferers from this group, who have followed Mark’s diet, have

> found that their symptoms have improved. Mark’s diet would promote the

> healing of intestinal permeability (depending on the cause).

>

> 11. cea is a chronic, stubborn disease that is difficult to cure.

> Healing a leaky gut requires many months of controlled diet and probably

> other factors too (anti-fungals, nutritional supplements). If it is not

> treated, it is unlikely to resolve itself. If “Leaky Gut” syndrome were the

> cause of rosacea, it would not be surprising that so few rosacea sufferers

> go into spontaneous remission, but in fact suffer the disease for many years

> or even indefinitely.

>

> ______________________________________________

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>

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[Guest guest]

Where can I find more info about " leaky gut syndrome " .

Judy M

cea and intestinal permeability...

Hello group.

A few months ago, I posted a message discussing the possible link between

rosacea and " leaky gut " syndrome. I was wondering if anyone had been giving

this any further thought and also I thought I'd let you know about a recent

development.

Basically, to recap " leaky gut " syndrome (or more formally intestinal

hyperpermeability) is a condition where the digestive tract becomes

excessively porous and as a result undesirable material (such as partially

digested food, bacteria, toxins etc.) are able to escape into the blood

stream. This may sound gruesome, but in fact the condition is considered to

be relatively common and it may not cause any noticeable symptoms.

As I mentioned in my previous post, I believe there are number of reasons

that support the idea that " leaky gut " syndrome might play a role in the

pathogenesis of rosacea. (See the end of this email for a summary of these

main reasons.)

Fortunately, there is a relatively simple urine test to confirm the

existence of this condition. I decided to ask my (new) doctor what she

thought about this and also to ask her if I could take such a test.

Unfortunately, she was not as open minded as my previous doctor - she

insisted that rosacea was just a form of teenage acne and she refused to

submit me for such a test. I was thoroughly disappointed, not least because

it was quite obvious that she really didn't know very much about rosacea.

I'm not trying to claim that I am a medical expert, but I have read a great

deal of medical literature concerning this disease (as I'm sure many of you

have) and many of the things she was saying were in direct conflict with

this. Anyway, that was the end of that.

However, about a month later I was surfing the net and I discovered a

medical lab in the UK (where I live) that would perform such a test by mail

order. (For those who are interested, they used the PEG 400 test, which

uses a variety of different molecular sizes, not the lactulose/mannitol,

which only uses two.) The only proviso was that they would only send the

results to my doctor. After confirming with another doctor at my surgery,

that it would be ok for him to receive my results, I underwent the test.

About a week later the results came back and they showed that throughout the

mid-range of molecular sizes, my intestinal permeability was well above the

upper-limit of normal (by about twice the normal range). The doctor was

quite surprised by the result. He gave me a blood test for common food

allergies (which regularly causes increased permeability), but these were

negative and he has made an appointment for me to see a gastroenterologist.

Anyway, the web site address for the lab that performed this test is

http://www.biolab.co.uk and the test costs £40. I'm sure there are similar

labs in the US and elsewhere. I would be very interested to hear of any

other rosacea sufferers who were motivated enough to undergo such a test. I

would like to point out that I have never considered my self to have any

sort of digestive disease.

I look forward to any replies.

Best regards,

Seth

P.S. I thought I would include a quick summary of the main reasons that

support the association between intestinal permeability and rosacea.

1. There has been a long history of association between digestive

disturbance and rosacea.

2. cea has long been linked to Irritable Bowel Disease (Crohn's disease

and Ulcerative Colitis). It is now a well-established fact that patients

with these diseases have increased intestinal permeability and that the

level of intestinal permeability correlates well with the severity of their

disease.

3. Antibiotics are known to be effective in the treatment of many cases of

rosacea and they are also known (in the short-term) to reduce intestinal

permeability in many cases. Also the antibiotics that are effective in

rosacea (for example, tetracycline and metronidazole) are also the most

effective at reducing intestinal permeability as well as improving diseases

such as Crohn's (in the short term). (Please note that antibiotics are also

believed to be an important cause of Leaky Gut Syndrome.)

4. cea patients often complain of food allergy. As mentioned, food

allergy commonly causes increased intestinal permeability (as does any form

of inflammation of the intestinal tract.)

5. cea patients often complain of autoimmune disorders (for example

arthritis or Raynaud's (intense coldness of fingers, toes, nose or even

body)) and it has been shown that rosacea patients are more likely to test

positively for ANA. This could well be explained by the body being exposed

to a variety of allergens leaking into the blood stream from the intestines

and that these send the immune system into overdrive.

6. As we all know, the bacterium that causes stomach ulcers H. Pylori has

been tentatively linked to rosacea. It is well known that H. Pylori

infection commonly increases gastric permeability.

7. cea has been linked to hypochlorhydria (reduced production of

stomach acid). This can commonly lead to increased intestinal permeability

by (a) not killing bacteria in the stomach and letting them progress through

to the intestines and ( by only partially digesting proteins this food can

cause " unfriendly bacteria " to thrive in the intestines. In both cases this

intestinal dysbiosis can quickly irritate and inflame the intestinal wall

and lead to increased permeability.

8. Many women have found that their rosacea either worsens or even begins

following pregnancy. Apparently, during pregnancy intestinal permeability

increases. Many women have also found that taking the birth control pill can

worsen the rosacea symptoms. Apparently this too, can increase intestinal

permeability. (Unfortunately I cannot remember where I read this.)

9. Many rosacea patients (on this group) apparently have problems with

candida overgrowth. Again this is apparently a well-known cause of " Leaky

Gut " syndrome.

10. cea sufferers from this group, who have followed Mark's diet, have

found that their symptoms have improved. Mark's diet would promote the

healing of intestinal permeability (depending on the cause).

11. cea is a chronic, stubborn disease that is difficult to cure.

Healing a leaky gut requires many months of controlled diet and probably

other factors too (anti-fungals, nutritional supplements). If it is not

treated, it is unlikely to resolve itself. If " Leaky Gut " syndrome were the

cause of rosacea, it would not be surprising that so few rosacea sufferers

go into spontaneous remission, but in fact suffer the disease for many years

or even indefinitely.

______________________________________________

FREE Personalized Email at Mail.com

Sign up at http://www.mail.com/?sr=signup

-----------------------------------------------------------------

Please read the list highlights thoroughly before posting to the whole

group. See http://rosacea.ii.net/toc.html

When replying, please delete all text at the end of your email that isn't

necessary for your message.

To leave the list send an email to rosacea-support-unsubscribeegroups