Information supporting Dr. Wakefield's findings

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From: sylviasage2001@...Reply-to: CasiClubhouse To: CasiClubhouse Sent: 2/10/2010 8:30:19 A.M. Eastern Standard TimeSubj: [bad text]

Comment: The Lancet editor admitted that Wakefield et al's speculation about a possible MMR/autism connection (1) was the primary reason for the retraction. Ironically, as Wakefield et al 1998 was headed for publication, the journal Pediatrics was preparing a study the reported a range of adverse effects associated with MMR vaccinations but not with related mono- and bi-valent vaccines (2). Speculating about a possible autism-MMR connection merited retraction, but not so for a study that reported "Eight children died, and the remainder had mental regression and retardation, chronic seizures, motor and sensory deficits, and movement disorders." (2)

1. Ileal-lymphoid- nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.Wakefield AJ, Murch SH, A, Linnell J, Casson DM, Malik M, Berelowitz M, Dhillon AP, Thomson MA, Harvey P, Valentine A, Davies SE, - JA. Lancet. 1998 Feb 28;351(9103) :637-41.

2. [Highlights added in abstract]Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines: A Review of Claims Submitted to the National Vaccine Injury Compensation Program E. Weibel*, Vito Caserta*, E. Benor Dagger, and Geoffrey *>From the * Division of Vaccine Injury Compensation, National Vaccine Injury Compensation Program, Health Resources and Services Administration, Public Health Service, Rockville, land; and the DaggerOffice of the General Counsel, United States Department of Health and Human Services, Rockville, land.PEDIATRICS Vol. 101 No. 3 March 1998, pp. 383-387$ http://pediatrics. aappublications. org/cgi/content/ abstract/ 101/3/383Objective. To determine if there is evidence for a causal relationship between acute encephalopathy followed by permanent brain injury or death associated with the administration of further attenuated measles vaccines (Attenuvax or Lirugen, Hoechst n Roussel, Kansas City, MO), mumps vaccine (Mumpsvax, Merck and Co, Inc, West Point, PA), or rubella vaccines (Meruvax or Meruvax II, Merck and Co, Inc, West Point, PA), combined measles and rubella vaccine (M-R-Vax or M-R-Vax II, Merck and Co, Inc, West Point, PA), or combined measles, mumps, and rubella vaccine (M-M-R or M-M-R II, Merck and Co, Inc, West Point, PA), the lead author reviewed claims submitted to the National Vaccine Injury Compensation Program.Methods. The medical records of children who met the inclusion criteria of receiving the first dose of these vaccines between 1970 and 1993 and who developed such an encephalopathy with no determined cause within 15 days were identified and analyzed. Results. A total of 48 children, ages 10 to 49 months, met the inclusion criteria after receiving measles vaccine, alone or in combination. Eight children died, and the remainder had mental regression and retardation, chronic seizures, motor and sensory deficits, and movement disorders. The onset of neurologic signs or symptoms occurred with a nonrandom, statistically significant distribution of cases on days 8 and 9. No cases were identified after the administration of monovalent mumps or rubella vaccine. Conclusions. This clustering suggests that a causal relationship between measles vaccine and encephalopathy may exist as a rare complication of measles immunization.

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