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>1oz. dndelion

>1oz. parslty root

>1oz. balm herb

>1/2 oz ginger root

>1/2 oz licorice root (or liqcorice)

>Place in 2 quarts of water, gently simmer down to 1 quart, strain.

>Take one wine glass every 2 hours.

How often do you take this? Every day? A warning from an

herbalist, be careful with licorice root...if you have high blood

pressure, avoid it, although it is helped in this formula by the

diuretic herb mentioned in the list, parsley root.

L. Meydrech, CN

http://nutritionist.tripod.com/gallbladder.html ~ My Flushes

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FREE Health Analysis:

http://www.mynsp.com/web/meydrech/healthAnalyzer.jsp

mailto:claudiameydrech@...

" A cheerful heart is good medicine " Prov. 17:22a

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What?? Now we're related?? Thought I was the only Bozo here,

<grin> Thanks for the chuckle Arleen, Lord knows we all need

one every now and then.

Jim(ms)

----- Original Message -----

From: Amsmmiii@...

low dose naltrexone

Sent: Thursday, April 29, 2004 11:07 AM

Subject: Re: [low dose naltrexone] Thanks

It's OK Rob, we're all bozo's on this bus! ...Arleen

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-----Original Message-----From: Louise de la Lande [mailto:ldelalande@...]Sent: Tuesday, May 18, 2004 12:30 AMlowdosenattrexone Subject: Thanks

Hi lesa and to all who replied to my call for 1.5 and 2.0 ldn people,

Thanks for the kind words lesa

and to all on the lowdose KEEP POSTING..........

Louise OZ

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Naltrexone at low doses (together with morphine) can actually help

reduce certain kinds of pain and even potentiates the action of

morphine. This is different from what Dr.Bihari says.

Yash

SOUTH SAN FRANCISCO, Calif., April 27 /PRNewswire-FirstCall/ -- Pain

Therapeutics, Inc. (Nasdaq: PTIE), a biopharmaceutical company,

today announced positive pre-clinical data on a novel treatment for

neuropathic pain. The Company will present its pre-clinical data at

the Scientific Meeting of the American and Canadian Pain Societies

on Friday, May 7, 2004 in Vancouver, Canada.

Pain Therapeutics' new data opens up the possibility of using its

technology to treat neuropathic pain, a chronic condition that

affects 2 to 3 million Americans and a new area of focus for the

Company.

" We are excited about the possibility of using our novel technology

in the area of neuropathic pain, " said Remi Barbier, Pain

Therapeutics' president and chief executive officer. " Moderate-to-

severe neuropathic pain is typically poorly managed by existing

drugs, is often under-diagnosed and affects a large patient

population. We believe a novel drug that provides effective pain

relief would bring significant advantages for patients who endure

this chronic condition. "

" Neuropathic pain represents a substantial unmet medical need, " said

Nadav Friedmann, Ph.D., MD, chief operating officer of Pain

Therapeutics. " Opioid drugs, such as morphine or oxycodone, are

generally viewed as ineffective in relieving chronic pain caused by

nerve damage. Our own pre-clinical data confirms this view. However,

new data show that ultra-low-dose naltrexone co-administered with an

opioid drug greatly attenuates neuropathic pain sensitivity. These

pre-clinical data are encouraging, as they may allow us to develop a

novel and effective opioid drug to treat neuropathic pain. "

Spending for neuropathic pain is included in the Company's prior

financial guidance for 2004.

Technical Poster Synopsis

" Ultra-low-dose Naltrexone Plus Morphine Blocks Thermal Hyperalgesia

and Attenuates Mechanical Hypersensitivity In A Neuropathic Pain

Model "

by Todd W. Vanderah, Ph.D., Assistant Professor of Anesthesiology

and Pharmacology, University of Arizona and H. Burns, Ph.D.,

Director of Pre-clinical Research at Pain Therapeutics, Inc.

This poster presents the methods and results of a first

investigation of an opium-based drug (morphine) combined with a low-

dose opioid antagonist (naltrexone) in a pre-clinical model of

neuropathic pain. In this experiment, a total of 42 rats underwent

surgical ligation of spinal nerves (L5 and L6) and were tested for

thermal and tactile hyperalgesia (enhanced sensitivity to pain) for

7 days following surgery. The 42 rats were divided into 6 treatment

groups: placebo, morphine alone, naltrexone alone and three groups

receiving various morphine/ultra-low-dose naltrexone combinations.

Placebo or naltrexone alone had no effect on hyperalgesia. Morphine

alone had a partial and transient effect on hyperalgesia. All groups

receiving morphine/ultra- low-dose naltrexone combinations, however,

showed significant anti- hyperalgesia compared to morphine alone or

placebo for the entire week of testing (p<0.001). Morphine/ultra-low-

dose naltrexone also provided significant anti-hypersensitivity to

tactile stimuli (p<0.001). These pre-clinical data suggest that

neuropathic pain and morphine-induced hyperalgesia share a common

mechanism of action, i.e., excitatory signaling of opioid receptors.

The prolonged anti-hyperalgesic effects demonstrated here compared

to morphine alone suggests an opioid agonist/ultra-low-dose

antagonist combination could be an effective treatment for

neuropathic pain.

About Neuropathic Pain

Neuropathic pain is a chronic condition caused by nerve injury.

Patients with neuropathic pain typically develop a painful super-

sensitivity (hyperalgesia) to touch, heat or other stimuli. A number

of medical conditions can lead to neuropathic pain, including

diabetic neuropathy, HIV/AIDS neuropathy, phantom limb pain, spinal

cord injury or multiple sclerosis.

At least 1% of the United States population (2-3 million people)

suffers from neuropathic pain. There are few truly effective, well-

tolerated drug therapies to treat neuropathic pain. A variety of

classes of drugs, such as opioids, tricyclic antidepressants or anti-

epileptic agents (e.g. gabapentin), typically offer partial or

transient relief from neuropathic pain.

> Thanks to Tom Aegis and friday for all replying very kindly to my

> " ethical dilemma " post.

> I do wonder though whether Aegis's ldn as an opiate potentiate

article is

> the same as friday referred to in the BOSTONCURE website?? Dr

Bihari warns

> people that people that opiates are contraindicated for ldn??

>

> Louise (OZ)

> PS friday thanks for the links

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  • 3 months later...

--- In , " cox58asthma " <cox58asthma@y...>

wrote:

>

>

> Doug,

>

> Just wanted to say thanks for starting this group. When I found

it,

> I never realized how much better just reading everyones posts and

> being able to " talk " with someone who also knows how I feel would

> make me feel. This has really helped me alot, as I was getting

> really depressed because nothing seemes to help my asthma and you

> guys have given me hope.

>

> Also thanks to Pandora and Sister Volz for the tips. I worked

> on my bedroom yesterday, put on dustmite covers on the matress and

> pillows, washed everything washable, dusted, etc. Also got the

> courage to vacuum with my HEPA vacuum, I wore a mask while I was

> doing all this and it didn't seem to make me too much worse. I

> think it was worth it because I woke up feeling better than I have

> in a long time.

>

> I've been reading more of the posts every day and there is alot of

> really good info.

>

> Addy - hope you get to feeling better.

>

> Everyone, thanks for being there.

>

>

,

You are quite welcome :) Hey, my mother's maiden name was . Maybe

we are related!

Doug

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Doug,

is my married name, My husband is Del Ray. His family has lived

right around on, Mo since comming from Kentucky back in horse

and buggy days.-There's alot of 's around here, some are related

and some are not.

Happy Halloween

-

- In , " Doug " <uca79ii@y...> wrote:

>

>

>

> >

> >

> > Doug,

> >

> > Just wanted to say thanks for starting this group. When I found

> it,

> > I never realized how much better just reading everyones posts

and

> > being able to " talk " with someone who also knows how I feel

would

> > make me feel. This has really helped me alot, as I was getting

> > really depressed because nothing seemes to help my asthma and

you

> > guys have given me hope.

> >

> > Also thanks to Pandora and Sister Volz for the tips. I

worked

> > on my bedroom yesterday, put on dustmite covers on the matress

and

> > pillows, washed everything washable, dusted, etc. Also got the

> > courage to vacuum with my HEPA vacuum, I wore a mask while I was

> > doing all this and it didn't seem to make me too much worse. I

> > think it was worth it because I woke up feeling better than I

have

> > in a long time.

> >

> > I've been reading more of the posts every day and there is alot

of

> > really good info.

> >

> > Addy - hope you get to feeling better.

> >

> > Everyone, thanks for being there.

> >

> >

>

> ,

>

> You are quite welcome :) Hey, my mother's maiden name was .

Maybe

> we are related!

>

> Doug

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  • 3 years later...

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