SchaferAutismReport: Seizure concern: Split Up Chickenpox, MMR Vaccines

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PUBLIC HEALTHSeizure Concern: Split Up Chickenpox, MMR Vaccines By Liz Szabo, USA TODAY http://xrl.in/5qzs

The CDC is recommending that the chickenpox vaccine and the MMR shot be given separately to avoid the risk of febrile seizures. Fever-related seizures in toddlers are scary but not serious. By Noel Celis, AFP/Getty Images. Combining two common childhood immunizations — the chickenpox vaccine and the joint measles, mumps and rubella shot, or MMR — slightly increases

the risk of fever-related seizures in toddlers, a new study shows. Authors note that the overall risk of seizures is very low. All four vaccinations are critically important, and experts say that children shouldn't skip or delay any of them. And while fever-related seizures may be frightening to parents, they aren't actually serious and don't cause permanent harm, says Nicola Klein, author of the study in today's Pediatrics. Parents who are concerned may want to ask for two separate shots — MMR and chickenpox — instead of taking the four-in-one combination called ProQuad, says Klein, co-director of the Kaiser Permanente Vaccine Study Center in California. In a study of 459,000 kids, she found that ProQuad caused one extra seizure for every 2,300 doses. Risk increased only in kids ages 1 to 2, however, and only

during a three-day window, seven to 10 days after injection. The Centers for Disease Control and Prevention last year changed its vaccine recommendations based on Klein's preliminary findings. Although the CDC typically prefers to combine shots — partly to spare kids from extra needle sticks — it now recommends that children whose parents don't have a strong preference get the chickenpox vaccine and the MMR shots separately. Both shots can be given on the same day. There is no need to split up the MMR shot, because that combination poses no extra risks, says

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