SchaferAutismReport: Research Builds on Genetic Link to Autism and Schizophrenia

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Subject: Research Builds on Genetic Link to Autism and Schizophrenia

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RESEARCH

Research Builds on

Genetic Link to Autism and Schizophrenia

is.gd/981KG

ScienceDaily — A genetic link

between schizophrenia and autism is enabling researchers to study the

effectiveness of drugs used to treat both illnesses.

Dr Steve Clapcote from the University of

Leeds's Faculty of Biological Sciences will be analysing behaviour

displayed by mice with a

genetic mutation linked to schizophrenia and autism and seeing

how antipsychotic drugs affect their behavioural abnormalities.

" We don't fully understand how the drugs

used to treat schizophrenia and some symptoms of autism work, " explained

Dr Clapcote. " If we can show they can affect mice with this particular

genetic mutation, then it gives us a clue to better understand the illnesses

and opens up the possibility of more targeted treatments with fewer side

effects. "

A number of autism and schizophrenia patients

have been found to have mutations of neurexin 1a, a protein which helps to

form and maintain nerve signals in the brain. Scientists in the USA recently

discovered that mice with the same genetic mutation display behavioural

abnormalities which are consistent with schizophrenia and autism.

Dr Clapcote is planning to build on these initial

findings to provide further evidence for a genetic link to the conditions. He

also aims to assess the impact on the mice of antipsychotic drugs used to

treat schizophrenia and some symptoms of autism.

" The genetic studies so far are

suggesting a common cause for both schizophrenia and autism, which is

something our studies will help to establish, " said Dr Clapcote.

" However, these illnesses are complex, involving not only inheritance,

but other factors such as environment and experience. It's possible the

genetic mutation might create a predisposition, making people more

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RESEARCH

Research Builds on Genetic Link to Autism and Schizophrenia

Autism Signs Appear In Babies' First Year, But Parents Don't Notice, Study

Finds

PUBLIC HEALTH

Congress Asked to Investigate Vaccine Safety

BULLYING NEWS

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Facebook Group Targets Down's Syndrome Kids In Italy

FINANCES

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Michigan Mandated Insurance Coverage of Autism Proposed

EDUCATION

Sales of Artwork to Benefit Children’s Educational Programs

TREATMENT

Dr. Krigsman Leaving Thoughtful House

RESOURCES

41 Things to Know About Autism

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Illinois Autism Awareness License Plates Show Support

COMMENTARY

Is There A Link Between Childhood Vaccines And Autism?

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