Re: Implant education..Thank you, Dede:

[Guest guest]

Dede, you are our Special Angel:

This is great, you are moving ahead very quickly in you quest for the truth. My research was based on what the manufacturers did to cover their butts, and the diseases that silicone causes. It took fifteen years to get to the Forensic studies, and then I was to sick to continue. My plan is to continue, when we get settled in our home.

Take care of our Dede....sending love to you...Lea and Superman

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Implant education

The effect of silicones on the immune function is not fully characterized.In clinical and experimental studies, immune alterations associated withsilicone gel seem to be related to macrophage activation. In this work weexamined in vivo, phenotypic and functional changes on peritonealmacrophages early (24 h or 48 h) and late (45 days) after theintraperitoneal (i.p.) injection of dimethylpolysiloxane (DMPS) (silicone).We studied the expression of adhesion and co-stimulatory molecules and boththe spontaneous and the stimulated production of reactive oxygenintermediates and nitric oxide (NO). ResultsThe results presented here demonstrate that the fluid compound DMPS induceda persistent cell recruitment at the site of the injection. Besides, cellactivation was still evident 45 days after the silicone injection: activatedmacrophages exhibited an increased expression of adhesion (CD54 and CD44)and co-stimulatory molecules (CD86) and an enhanced production of oxidantmetabolites and NO. ConclusionsSilicones induced a persistent recruitment of leukocytes at the site of theinjection and macrophage activation was still evident 45 days after theinjection. BackgroundNowadays we are in permanent contact with silicones, synthetic polymerscontaining a repeating Si-O backbone and organic groups attached to thesilicon atom [1<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B1> ].Medical-grade silicones consist primarily of dimethylpolysiloxane (DMPS) andare widely used in devices including cardiac valves, intravenous tubing,intraocular lenses, digital joint arthroplasty prostheses, breast implants,syringes, needles, baby bottle nipples and many others products [1<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B1> ].Depending upon the length of the polymer chains and the amount ofcross-linking between chains medical-grade silicones can be found as fluids,gels or elastomers.The effect of silicones on the immune function is not fully characterized.It has been shown that certain forms of silicone are immunologically active[2 <http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B2> ]and depending upon the molecular weight and the degree of cross-linking ofthe polymers, silicones are potent humoral adjuvants [3<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B3> ].Several studies of the silicone-induced inflammatory response in patientsand animals revealed histopathological findings instead of direct evidencesof cellular activation [4<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B4> -6<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B6> ].The initial body's reaction to the implanted material is the inflammatoryresponse that induces recruitment and activation of different cells [7<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B7> ]. Themagnitude of any inflammatory response can be related to the level ofactivation of macrophages. This activation occurs both in inflammatory andin adaptive immune responses, and involves phenotypic and functional changes[8 <http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B8> ].Criteria widely used for activation are the ability to inhibit intracellularproliferation of microorganisms, the increased production of reactive oxygenintermediates and the enhanced expression of MHC and co-stimulatorymolecules [9<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B9> ,10<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B10> ].Recently, Naim et al. showed that silicone elastomer preadsorbed with plasmaproteins activated human monocytes in vitro to secrete pro-inflammatorycytokines [11<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B11> ].Besides, silicone gels and oils activated macrophages in female A.SW mice:increased production of IL-6 and IL-1â was obtained from macrophagescollected from silicone fluid- and silicone oil-treated mice when culturedwith increasing amounts of lipopolysaccharide [12<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237#B12> ].From the website:http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=117237 and have him read this:

http://www.fda.gov/cdrh/ost/reports/fy98/IMMUNOTOX.HTM

and have him read this:

http://www.publichealthalert.org/BIOTOXINS-Forsgren.pdf

Show him this blob of silicone, this is Dr Melmed:

Have him read this article:

http://lib.bioinfo.pl/meid:76594,

Am Rev Respir Dis. 1993 May ;147 (5):1299-302 8484647 [Cited: 4]

Silicone fluid-induced pulmonary embolism.

[My paper] Y M Chen , C C Lu , R P Perng

Silicone fluid injection for mammary augmentation is a well-known illegal procedure. It has been associated with many complications, including local tissue granulomatous reaction, chronic infection, and sclerosis, but pulmonary involvement in human beings has been documented in only six cases. We describe three more such cases of pulmonary embolism. These three patients were all female, young, and previously healthy. They received the procedures only for cosmetic reasons. Unfortunately, one of them died and another lived with the sequelae of pulmonary fibrosis. The mortality rate of the nine total patients with pulmonary embolism induced by silicone fluid, including our three cases, is 33%. Because of this high mortality rate and long-term sequelae of pulmonary fibrosis, no silicone fluid injection should be given for cosmetic reasons, especially in mammary augmentation in which a large volume of silicone fluid is more likely to be used, and the early use of corticosteroid therapy may be helpful.

see this, it is a safe implant.

Per: doctors, FDA, and drug companies

The FDA says about 6 percent get

necrosis, hum...300,000 people implants

in 2005, hum.......so, how many is that?

its huge ! now check this out, these are very safe: NOT !

Look at these lovely safe saline implants:

I will send a court document of the ingredients that Patty posted

not long ago, so he can see the " SAFE " ingredients in them.

and a report on silicone immune toxicity

REMEMBER ALL implants are silicone

some are saline filled and some are silicone filled.....

Start the year off right. Easy ways to stay in shape in the new year.