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Re: Latest on bezafibrate (from Japan)

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That is very exciting - thanks for keeping us updated. Two

questions for those of you who have a better understanding of this

than I do - 1) is there anything out there demonstrating

histological benefits (as i understand it, that would basically mean

better biopsy results as opposed to just better lab tests) and 2)

does anyone understand the relationship between bezafibrate and

fenofibrate? Bezafibrate is not available in the U.S., while

fenofibrate is, and given my total lack of chemistry background I

just do not understand if it should be expected that these

bezafibrate findings would translate into similar effects from

fenofibrate. Thanks,

Nina

husband PSC 4/06

CONCLUSIONS: Bezafibrate significantly reduced the level

> of biliary enzymes in various chronic liver diseases and may be

> useful for the treatment of certain liver disease subsets. PMID:

> 16933007.

>

> Dave

> (father of (21); PSC 07/03; UC 08/03)

>

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