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, I don't know the answer, just want to say that I keep coming up with

high levels of C reactive protein. Can't figure out why.

> Hello,

> Has anyone heard that a very low CRP also could imply hypercoagulation?

> I just heard this from my doctor today.

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So did mine. Then I did not know how to push him with it after we got the

results. Like what to do next. I was telling him I was achy all the time,

etc. (Have had sed rate checked, is low)

> My doc ordered it because he said it is an indicator of inflammation.

C

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  • 7 months later...

My rheumetologist said that elevated C reactive protein is an indication of

inflammation. I'm not sure of the scientific reason, just what my

rheumetologist told me.

lindaj@...

C reactive protein

> My C reactive protein is 400% of the top normal. score. I am still

waiting

> for the word from my immunologist as to what this means. Is it an

objective

> measure that indicate that you should feel bad. It is am accepted test.

>

> thanks

>

> Steve

>

>

>

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Steve,

I don't know how C Reactive protein or figures into CFS but it has been

found to correlate with heart attack risk. I think it's even more

predictive than cholesterol levels. May want to consult with a cardiologist

in addition to the immunologist. Steve B.

>From: " " <moores@...>

>Reply-

>< >

>Subject: C reactive protein

>Date: Fri, 28 Dec 2001 18:34:44 -0600

>

>My C reactive protein is 400% of the top normal. score. I am still

>waiting

>for the word from my immunologist as to what this means. Is it an objective

>measure that indicate that you should feel bad. It is am accepted test.

>

>thanks

>

>Steve

>

>

>

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Tp confirm, my family MD told me the same thing (mine is high) ...and

that it was also indicative of heart problems...he also said that w

someone like me inflammation comes and goes and tests will be

different on different days so impossible to get a good reading.

Hmm.

> My rheumetologist said that elevated C reactive protein is an

indication of

> inflammation. I'm not sure of the scientific reason, just what my

> rheumetologist told me.

>

>

> lindaj@h...

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  • 1 year later...

> hi everyone....just wondering if others have elevated c rective

> protein...just got blood test and that is high along with sed rate,

> liver enzymes, and cpk level. this is all normal since my

diagnosis

> but they just checked the c reactive protien for the first time. i

> think i have read that this can be sign of hidden infection? hope

> everyone is doing well.

>

> rachael

>

> dermatomyositis 10 years

> AP 5 weeks

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My CRP is high as well--130 with a ESR of 60--and we can't seem to get it

down.

(RA 25+ years, AP since Nov. 97)

rheumatic Re: c reactive protein

>

> > hi everyone....just wondering if others have elevated c rective

> > protein...just got blood test and that is high along with sed rate,

> > liver enzymes, and cpk level. this is all normal since my

> diagnosis

> > but they just checked the c reactive protien for the first time. i

> > think i have read that this can be sign of hidden infection? hope

> > everyone is doing well.

> >

> > rachael

> >

> > dermatomyositis 10 years

> > AP 5 weeks

>

>

> To unsubscribe, email: rheumatic-unsubscribeegroups

>

>

>

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  • 3 years later...

CRP is a precursor to the SED rate. It's being found to show inflammation

quicker. It was first noticed that heart attack patients had a high CRP hours

before their SED rate jumped. Now alot of docs use it to check for new onset

problems.

What was the CRP? Macey had one last week and it was 1.0 and she had 6 Monos on

her diff. They said it could be anything from getting upset due to 3 needle

sticks to her arthritis acting up. She also had a repeat ANA which was

negative.

She's had alot of fatigue lately but her other labs are all good. So her immuno

chalks it up to chronic illness (going on year 10 now) and some autoimmune

process we just can't pinpoint.

Ursula - mom to (14) and Macey (11, CVID)

http://www.primaryimmune.org

http://www.jmfworld.org

http://members.cox.net/maceyh

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Valarie,

this may sound really stupid....but Brennan is on IVIG right?

Sorry....I know you have one that is being tested and not sure if it

ia Brennan.

You made me realize something with your last post. Before Molly

started IVIG a year ago today, we would be out doing something (eg:

I remember a really bad incident at Walmart), she would start to

complain that her legs hurt.....suddenly. Molly is a tough cookie.

At Walmart, we were in the linens' section and she was walking and

was fine....then suddenly, her legs were hurting horribly. She

started to cry....which went on to horrific screaming to where she

could not stand. Her aunt was with us and we were

terrified....having no idea what was going on with her. We came

VERY close to calling an ambulance. We picked her up and put her in

the cart....gave her some juice and let her rest and it resolved in

a few minutes. I never thought about it again until after your most

recent post. We had many episodes like this.....they usually

corresponded to unexplainable sudden episodes of very high fevers

that would go away as fast as they happened with no illness

developing. After starting IVIG, we have never had another episode

of either fevers of leg pain like that.....she does get leg pain

when her Ig levels are not high enough...but nothing like that.

Molly tends to not drink enough and is always dehydrated when we

have her blood work drawn. I just always thought her leg and fever

stuff was related to dehydration....but I suppose it is more likely

due to her immune disorder since we have not had it happen again.

She has had an elevated ANA that has raised some red flags to watch

her for an autoimmune disorder....but they have not checked that for

quite a while now....but she is non-symptommatic too.

Terri

>

> Brennan is 4, 32 lbs, and his CRP was 1.1. So its slightly

elevated,

> Dr said for his age up to like, .8 is normal. However, his ANC has

> been cyclically low for nearly a yr......it goes way up, then back

> down to low 1's. His vial for the sed rate clotted so we need to

do it

> again.

>

> Thats what we are looking at, is autoimmune stuff. I am curious bc

> often he has pain so terrible, for the last few yrs, I have taken

him

> for xrays bc he couldnt move an arm or leg for DAYS--and its not

> faking, he seriuosly cannot move. Or he will just drop, and his leg

> will hurt so much for hours on end, he cant stand up........he'll

just

> drag his leg around and army crawl until it gets a little better.

> Usually the next day he is ok, but not always. When he was 2, he

was

> noted to have some signs of crepitus we thought was from chronic

> steroid use.

>

> sigh.

>

> gosh, he is only 4!! I feel so bad for him sometimes.

>

> thanks for the info.

>

> valarie

>

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At 5 years old Macey was at Duke being worked up for JRA. Literally she spent

her 5th birthday up here because that was the best week for me to leave the

nursing program and not miss any tests. So they did a spinal tap, ANA workup

(which included other tests besides the usual ANA but I can't remember what).

Then we saw the rheumy there and a developmental pediatrician. Macey had

complained for years about hand and knee pain. She would swell up and get these

nodules on her hands. Her knees never really showed any symptoms but we were

good at offering the usual bribes and tricks and she would pass them right by in

order to crawl into bed or soak in the tub. And this was a 5 yr old. She lived

on Advil at first and then they prescribed Naproxen. Naproxen is a prescriptive

Alleve but it required weekly blood work because it could cause damage.

We also saw some improvement when she was dosed at 800 or so mg/kg. We did some

xrays but mostly looked at physical symptoms. An MRI was mentioned but she

would have to be sedated for it and her lung function at the time was too

crappy.

She's 11 now and mostly we see knee and leg aches. Could be regular growing

pains but we dose with Advil and just remember to mention it at follow ups. She

knows what triggers it and slows down if she feels it coming on. But all of

that has come with time and experience. You can have an autoimmune problem and

have a negative ANA. We rely alot on CRP's, SED rates as backups, the mono

count on the differential and mostly on her say so. In a younger child blood

work can help tell the extent but lack of physical activity is very telling.

Big thing we learned in nursing school. Pain is what the patient says it is,

when the patient says it is. Err on the side of caution. Report each incident

and document everything with the docs. Medicate for comfort.

Ursula - mom to (14) and Macey (11, CVID)

http://www.primaryimmune.org

http://www.jmfworld.org

http://members.cox.net/maceyh

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  • 1 year later...
Guest guest

Hi ,

What length of time did it take for your CRP to jump to 80?

What did your doctor say about it?

I have no knowledge about this subject, so please keep us posted on it.

Patty

>

> Hello all! Has anyone ever had elevated CRP levels? I think it is

consistent with systemic

> inflammation but also a risk for cardiovascular disease. My level

has jumped to 80. Anything

> above 1 is abnormal. Any thoughts? Thanks,

>

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CRP (C-reactive Protein)

Test Overview

A C-reactive protein (CRP) test is a blood test that measures the amount of a protein called C-reactive protein in your blood. C-reactive protein measures general levels of inflammation in your body.

High levels of CRP are caused by infections and many long-term diseases. However, a CRP test cannot show where the inflammation is located or what is causing it. Other tests are needed to find the cause and location of the inflammation.

Why It Is Done

A C-reactive protein (CRP) test is done to:

Check for infection after surgery. CRP levels normally rise within 2 to 6 hours of surgery and then go down by the third day after surgery. If CRP levels stay elevated 3 days after surgery, an infection may be present. Identify and keep track of infections and diseases that cause inflammation, such as:

Cancer of the lymph nodes (lymphoma). Diseases of the immune system, such as lupus. Painful swelling of the blood vessels in the head and neck (giant cell arteritis). Painful swelling of the tissues that line the joints (rheumatoid arthritis). Swelling and bleeding of the intestines (inflammatory bowel disease). Infection of a bone (osteomyelitis).

Check to see how well treatment is working, such as treatment for cancer or for an infection. CRP levels go up quickly and then become normal quickly if you are responding to treatment measures.

A special type of CRP test, the high-sensitivity CRP test (hs-CRP), may be done to find out if you have an increased chance of having a sudden heart problem, such as a heart attack. Inflammation can damage the inner lining of the arteries and make having a heart attack more likely. However, the connection between high CRP levels and heart attack risk is not very well-understood.

Results

A C-reactive protein (CRP) test is a blood test that measures the amount of a protein called C-reactive protein in your blood.

Normal

Normal values may vary from lab to lab. Results are usually available within 24 hours.

C-reactive protein (CRP)

Normal:

0–1.0 mg/dL or less than 10 mg/L (SI units)

Any condition that results in sudden or severe inflammation may increase your CRP levels.

Some medicines may decrease your CRP levels.

High-sensitivity C-reactive protein (hs-CRP) levels

The hs-CRP test measures your risk for heart problems. It may be done to find out if you have an increased chance of having a sudden heart problem, such as a heart attack. However, the connection between high CRP levels and heart attack risk is not very well-understood.

High-sensitivity C-reactive protein (hs-CRP) levels

Less than 1.0 mg/L

Lowest risk

1.0 to 3.0 mg/L

Average risk

More than 3.0 mg/L

Highest risk

Many conditions can change CRP levels. Your doctor will talk with you about any abnormal results that may be related to your symptoms and medical history.

What Affects the Test

You may not be able to have the test or the results may not be helpful if:

You have just exercised.

You take certain medicines, such as hormone replacement therapy (HRT), birth control pills, nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, corticosteroids, or medicine to lower your cholesterol (for example, pravastatin).

You have an intrauterine device (IUD) in place.

You are pregnant.

You are very overweight (obese).

What To Think About

High-sensitivity C-reactive protein (hs-CRP) measures very low amounts of CRP in the blood. This test may be helpful in predicting your risk for heart problems, especially when it is combined with total cholesterol and HDL cholesterol tests.

High CRP levels before a major surgery may indicate that you are at risk for developing an infection after surgery.

CRP testing can be used to see how well you respond to cancer treatment or treatment for an infection. Your CRP levels will rise quickly and then quickly return to normal if the treatment is working.

High CRP levels may increase your chances of having other diseases, such as age-related macular degeneration and colon cancer.

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