Guest guest Posted January 16, 2011 Report Share Posted January 16, 2011 Latest Type 2 Issues Articles Scientists <http://www.diabeteshealth.com/read/2011/01/14/7014/scientists-cook-up-a-lit tle-brown-fat/> Cook Up a Little Brown Fat Fatty <http://www.diabeteshealth.com/read/2011/01/13/7012/fatty-liver-its-serious/ > Liver: It's Serious Walgreens <http://www.diabeteshealth.com/read/2011/01/12/7011/walgreens-in-south-flori da-and-diabetes-research-institute-foundation-announce-unique-partnership/> in South Florida and Diabetes Research Institute Foundation Announce Unique Partnership New <http://www.diabeteshealth.com/read/2011/01/11/7008/new-wound-treatment-for- non-healing-foot-ulcers/> Wound Treatment for Non-healing Foot Ulcers Diabetes <http://www.diabeteshealth.com/read/2011/01/11/7010/diabetes-management-in-f lu-season/> Management in Flu Season The <http://www.diabeteshealth.com/read/2011/01/10/7006/the-a1c-a-better-way-to- diagnose-pre-diabetes/> A1C: A Better Way to Diagnose Pre-Diabetes? Herbs, <http://www.diabeteshealth.com/read/2011/01/06/7002/herbs-sex-and-diabetes/> Sex, and Diabetes DiabetesSisters' <http://www.diabeteshealth.com/read/2011/01/05/7001/diabetessisters-national -conference-addresses-unique-challenges-of-women-with-diabetes/> National Conference Addresses Unique Challenges of Women with Diabetes UnitedHealthcare <http://www.diabeteshealth.com/read/2011/01/04/7003/unitedhealthcare-to-intr oduce-a-diabetes-prevention-program-in-rhode-island-in-2011/> to Introduce a Diabetes-Prevention Program in Rhode Island in 2011 Diabetic <http://www.diabeteshealth.com/read/2010/12/31/6998/divabetics-new-year-atti tude-be-healthy-and-happy-too/> 's New Year Attitude: Be Healthy & Happy Too! 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Halle <http://www.diabeteshealth.com/read/2008/12/25/5548/halle-berry-says-shes-wo rked-her-way-up-from-type-1-to-type-2-diabetes-/> Berry Says She's Worked Her Way Up From Type 1 to Type 2 Diabetes Data <http://www.diabeteshealth.com/read/2007/05/14/5189/data-suggest-cymbalta-re duced-severity-of-night-pain-in-patients-with-diabetic-nerve-pain/> Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain When <http://www.diabeteshealth.com/read/2008/09/22/5283/when-diabetes-leads-to-a -lazy-stomach-the-goods-on-gastroparesis/> Diabetes Leads to a Lazy Stomach: The Goods on Gastroparesis Doctors <http://www.diabeteshealth.com/read/2008/09/22/5619/doctors-say-avandia-warn ing-label-should-tout-vegan-diet/> Say Avandia Warning Label Should Tout Vegan Diet The <http://www.diabeteshealth.com/read/2008/09/22/3103/the-latest-scoop--on-ice -cream/> Latest 'Scoop' on Ice Cream Highly Recommended Type 2 Issues Articles Woman <http://www.diabeteshealth.com/read/2008/12/25/5870/woman-loses-134-pounds-i n-one-year/> Loses 134 Pounds in One Year Low <http://www.diabeteshealth.com/read/2008/12/25/5383/low-carbohydrate-diets-w hy-you-dont-want-the-experts-to-tell-you-what-to-eat/> Carbohydrate Diets: Why You Don't Want the " Experts " to Tell You What to Eat Insulin <http://www.diabeteshealth.com/read/2009/03/20/5564/insulin-for-type-2-diabe tes-who-when-and-why/> For Type 2 Diabetes: Who, When, And Why? Halle <http://www.diabeteshealth.com/read/2008/12/25/5548/halle-berry-says-shes-wo rked-her-way-up-from-type-1-to-type-2-diabetes-/> Berry Says She's Worked Her Way Up From Type 1 to Type 2 Diabetes Why <http://www.diabeteshealth.com/read/2007/04/24/5143/why-eating-too-many-carb s-makes-you-fat/> Eating Too Many Carbs Makes You Fat Mr. <http://www.diabeteshealth.com/read/2007/04/18/5130/mr--universes-police-run -in-becomes-a-force-for-education/> Universe's Police Run-In Becomes a Force for Education American <http://www.diabeteshealth.com/read/2008/12/17/5624/american-idols-elliott-y amin-brings-diabetes-message-to-millions/> Idol's Elliott Yamin Brings Diabetes Message to Millions Take <http://www.diabeteshealth.com/read/2008/12/17/5700/take-this-test-on-insuli n-you-may-be-smarter-than-a-doctor/> This Test on Insulin: You May Be Smarter Than a Doctor! When <http://www.diabeteshealth.com/read/2008/09/22/5283/when-diabetes-leads-to-a -lazy-stomach-the-goods-on-gastroparesis/> Diabetes Leads to a Lazy Stomach: The Goods on Gastroparesis Blood <http://www.diabeteshealth.com/read/2008/07/31/5850/blood-and-honey-a-doc-ab out-diabetes/> & Honey: A Doc About Diabetes <http://www.diabeteshealth.com/ads/www/delivery/ck.php?oaparams=2__bannerid= 692__zoneid=550__cb=e8e6087491__oadest=http%3A%2F%2Fad.doubleclick.net%2Fjum p%2FN5371.DiabetesHealth.com%2FB5028983.4%3Babr%3D%21ie4%3Babr%3D%21ie5%3Bsz %3D300x250%3Bpc%3D%5BTPAS_ID%5D%3Bord%3De8e6087491%3F> Advertisement Diabetes Health Reference Charts Insulin Pen Needles <http://www.diabeteshealth.com/charts/redirect/69> Reference Guide (PDF) Blood Glucose Meters <http://www.diabeteshealth.com/charts/redirect/73> Reference Guide (PDF) Lancing Devices <http://www.diabeteshealth.com/charts/redirect/75> Reference Guide (PDF) Insulin Reference Guide <http://www.diabeteshealth.com/charts/redirect/67> (PDF) Insulin Pumps Reference <http://www.diabeteshealth.com/charts/redirect/70> Guide (PDF) Mail Order Reference <http://www.diabeteshealth.com/charts/redirect/79> Guide (PDF) Insulin Pens Reference <http://www.diabeteshealth.com/charts/redirect/68> Guide (PDF) Infusion Sets Reference <http://www.diabeteshealth.com/charts/redirect/71> Guide (PDF) Type 2 Meds Reference <http://www.diabeteshealth.com/charts/redirect/74> Guide (PDF) Syringes Reference <http://www.diabeteshealth.com/charts/redirect/76> Guide (PDF) <http://www.diabeteshealth.com/charts/> See All Charts. Type 2 Issues Archives Browse <http://www.diabeteshealth.com/archive/community/type-2-issues/> the Type 2 Issues Archives Subscribe to the <http://www.diabeteshealth.com/feeds/community.xml> Community RSS Feed <http://www.diabeteshealth.com/apps/mobile/> Print <javascript:window.print()> | Email <javascript:toggleEmailPanel()> | Share <http://www.diabeteshealth.com/read/2011/01/13/7012/fatty-liver-its-serious/ #share#share> | Comments <http://www.diabeteshealth.com/read/2011/01/13/7012/fatty-liver-its-serious/ ?isComment=1#comments> (0) Email to a Friend Send a link to this page to your friends and colleagues. Your Name: Your Email: Recipient's Name: Recipient's Email: Close <javascript:toggleEmailPanel()> Nonalcoholic Fatty Liver Disease (NAFLD) Fatty Liver: It's Serious von Wartburg Jan 13, 2011 " Fatty liver " doesn't sound very threatening. In fact, it sounds almost cute, like Fatty Arbuckle. Unfortunately, like Fatty Arbuckle, it's not what it seems. Nonalcoholic fatty liver disease is the most common liver disease in the United States, comprising a quarter of all liver disease and responsible for a rising number of liver transplants. Approximately 20 percent of Americans may be lugging around a fatty liver. Because nonalcoholic fatty liver is associated with obesity and type 2 <http://www.diabeteshealth.com/browse/community/type-2-issues/> diabetes <http://www.diabeteshealth.com/> , its incidence is rising along with theirs. An estimated 70 to 90 percent of people with obesity and type 2 <http://www.diabeteshealth.com/browse/community/type-2-issues/> diabetes have some degree of fatty liver, apparently caused by the metabolic abnormalities that make up metabolic syndrome. These abnormalities, including excess body weight, insulin <http://www.diabeteshealth.com/browse/complications-and-care/insulin-resista nce/> resistance, and high triglyceride levels in the blood, cause fat to accumulate in liver cells. Nonalcoholic fatty liver disease ranges from simple steatosis, meaning " fattiness, " to nonalcoholic steatohepatitis (NASH), which means " fatty liver with inflammation, " all the way to cirrhosis of the liver. It resembles liver disease due to alcoholism, which also causes fatty liver, steatohepatitis, and cirrhosis but has a worse prognosis. Only about five to ten percent of people with nonalcoholic fatty liver go on to develop NASH. Of those, an estimated 3 to 26 percent develop cirrhosis. But what about the majority of people with fatty liver, those who don't develop NASH? Recent research indicates that they are still at an increased risk: of stroke. Between 2005 and 2009, researchers from St. 's Hospital in Ontario looked at 103 adults who had a stroke and found that they had high levels of markers indicating fatty liver disease compared to people who had not had a stroke. In a letter published in Endocrinology <http://www.diabeteshealth.com/browse/health-care/endocrinology/> , the researchers noted that people with fatty liver may be three times more likely to have a stroke than people without fatty liver. In an earlier study, published in 2009 in the New England Journal of Medicine, a connection between fatty liver and heart disease was reported. The authors cited evidence that people with NASH are twice as likely to die of heart attack or stroke as those without it. Overweight men with NASH have higher levels of C-reactive protein, an inflammatory factor, and fibrinogen, which causes clotting; the worse the NASH, the higher the levels. The authors hypothesized that these and other factors associated with fatty liver promote atherosclerosis, which damages arteries and increases the risk of clots, making heart attack and stroke more likely. Sources: MedicineNet.com e! 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