Several questions

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I wouldnt touch Phentermine with a 10 foot pole ! ! !

Phentermine Official FDA information, side effects and uses.

http://www.drugs.com/pro/phentermine.html

IF YOU WERE ILL FROM IMPLANT CHEMICALS I WOULD ABSOLUTELY

NOT TAKE A DRUG SIMILAR TO AMPHETAMINES ! ! IT ALSO HAS

TALC AND SILICONE DIOXIDE IN IT....

Phentermine hydrochloride is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether.Phentermine hydrochloride, an anorectic agent for oral administration, is available as a capsule.

Phentermine hydrochloride capsules 15 mg contain the inactive ingredients D & C Yellow #10 Aluminum Lake, FD & C Blue #1 Aluminum Lake, FD & C Red #3, FD & C Red #40 Aluminum Lake, Gelatin, Lactose Monohydrate, Magnesium Stearate, Talc and Titanium Dioxide.Phentermine hydrochloride capsules 30 mg and 37.5 mg contain the inactive ingredients D & C Red #33 (in 37.5 mg only), D & C Yellow #10 Aluminum Lake, FD & C Blue #1 Aluminum Lake, FD & C Blue #2 Aluminum Lake, FD & C Red #3 (in 30 mg only), FD & C Red #40 Aluminum Lake, Gelatin, Lactose Monohydrate, Magnesium Stearate, Pharmaceutical Glaze, Propylene Glycol, Silicon Dioxide, Sodium Lauryl Sulfate, Synthetic Black Iron Oxide, Talc and Titanium Dioxide.

Phentermine - Clinical Pharmacology

Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.

Contraindications

Advanced arteriosclerosis, cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma.Agitated states.

Patients with a history of drug abuse.During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result).

***Warnings Lots of them here....***

Phentermine hydrochloride tablets and capsules are indicated only as short-term monotherapy for the management of exogenous obesity. The safety and efficacy of combination therapy with Phentermine and any other drug products for weight loss, including selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. Therefore, coadministration of these drug products for weight loss is not recommended.Primary Pulmonary Hypertension (PPH) – a rare, frequently fatal disease of the lungs – has been reported to occur in patients receiving a combination of Phentermine with fenfluramine or dexfenfluramine. The possibility of an association between PPH and the use of Phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who reportedly have taken Phentermine alone. The initial symptom of PPH is usually dyspnea. Other initial symptoms include: angina pectoris, syncope or lower extremity edema. Patients should be advised to report immediately any deterioration in exercise tolerance. Treatment should be discontinued in patients who develop new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema.Valvular Heart Disease: Serious regurgitant cardiac valvular disease, primarily affecting the mitral, aortic and/or tricuspid valves, has been reported in otherwise healthy persons who had taken a combination of Phentermine with fenfluramine or dexfenfluramine for weight loss. The etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. The possibility of an association between valvular heart disease and the use of Phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken Phentermine alone.Tolerance to the anorectic effect usually develops within a few weeks. When this occurs, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued.Phentermine hydrochloride may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly.Usage with Alcohol: Concomitant use of alcohol with Phentermine hydrochloride may result in an adverse drug interaction.

Precautions

Caution is to be exercised in prescribing Phentermine hydrochloride for patients with even mild hypertension.Insulin requirements in diabetes mellitus may be altered in association with the use of Phentermine hydrochloride and the concomitant dietary regimen.Phentermine hydrochloride may decrease the hypotensive effect of guanethidine.The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage.Carcinogenesis, Mutagenesis, Impairment of Fertility

Studies have not been performed with Phentermine hydrochloride to determine the potential for carcinogenesis, mutagenesis or impairment of fertility.Pregnancy

Adverse Reactions

Cardiovascular: Primary pulmonary hypertension and/or regurgitant cardiac valvular disease (see WARNINGS), palpitation, tachycardia, elevation of blood pressure.Central Nervous System: Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, rarely psychotic episodes at recommended doses.Gastrointestinal: Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.Allergic: Urticaria.Endocrine: Impotence, changes in libido.

Drug Abuse and Dependence

Phentermine hydrochloride is related chemically and pharmacologically to the amphetamines. Amphetamines and related stimulant drugs have been extensively abused, and the possibility of abuse of Phentermine hydrochloride should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia.

Overdosage

Manifestations of acute overdosage with Phentermine include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma.Management of acute Phentermine intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. Acidification of the urine increases Phentermine excretion. Intravenous phentolamine has been suggested for possible acute, severe hypertension, if this complicates Phentermine overdosage.

Phentermine Official FDA information, side effects and uses.

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