RE: Lab-grown retina ups transplant hopes

[Guest guest]

Not sure what you mean. What is your eye problem--the actual diagnosis?

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Not sure what you mean. What is your eye problem--the actual diagnosis?

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Not sure what you mean. What is your eye problem--the actual diagnosis?

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Sounds exciting, but we've heard quite a few such reports over the years.

Putting on my cynic's cap again, and asking if this latest finding is so utterly

stunning, and could truly benefit so many people, why would it take 10 years to

begin helping humans? I get the sense some times that these people doing these

studies are really more about finding a nice little niche career, and the longer

they can draw out testing and research, and keep their funding, the longer they

have a nice paying job.

Okay, taking my cynic cap off now!

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Sounds exciting, but we've heard quite a few such reports over the years.

Putting on my cynic's cap again, and asking if this latest finding is so utterly

stunning, and could truly benefit so many people, why would it take 10 years to

begin helping humans? I get the sense some times that these people doing these

studies are really more about finding a nice little niche career, and the longer

they can draw out testing and research, and keep their funding, the longer they

have a nice paying job.

Okay, taking my cynic cap off now!

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Sounds exciting, but we've heard quite a few such reports over the years.

Putting on my cynic's cap again, and asking if this latest finding is so utterly

stunning, and could truly benefit so many people, why would it take 10 years to

begin helping humans? I get the sense some times that these people doing these

studies are really more about finding a nice little niche career, and the longer

they can draw out testing and research, and keep their funding, the longer they

have a nice paying job.

Okay, taking my cynic cap off now!

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

all I know is I was in a diabetic coma for two and one half days, they did

surgery , an exploratory to try and find out were an internal bleed was coming

from, lost six liters of blood. when I came too I was totally blind. they said

my organs were shutting down and they did not think I would make it. well I did

and said my nerve endings in my eyes were dead. this was eight years ago. now I

have nothing but blackness and just wondered if there was any hope at all. in

the meantime I am a realist and I go about my daily business and try to learn

all I can using the tools I have.

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

all I know is I was in a diabetic coma for two and one half days, they did

surgery , an exploratory to try and find out were an internal bleed was coming

from, lost six liters of blood. when I came too I was totally blind. they said

my organs were shutting down and they did not think I would make it. well I did

and said my nerve endings in my eyes were dead. this was eight years ago. now I

have nothing but blackness and just wondered if there was any hope at all. in

the meantime I am a realist and I go about my daily business and try to learn

all I can using the tools I have.

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

all I know is I was in a diabetic coma for two and one half days, they did

surgery , an exploratory to try and find out were an internal bleed was coming

from, lost six liters of blood. when I came too I was totally blind. they said

my organs were shutting down and they did not think I would make it. well I did

and said my nerve endings in my eyes were dead. this was eight years ago. now I

have nothing but blackness and just wondered if there was any hope at all. in

the meantime I am a realist and I go about my daily business and try to learn

all I can using the tools I have.

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Hmmm. I don't know a whole lot about the mechanics of the human eye, but I

believe the one thing that would take anyone out of the running for sight

restoration is a damaged or dead optic nerve. When you say " nerve damage " it's

hard to say what happened to you. As I just said, there is your optic nerve, so

I don't know. Whatever happened to you sounds traumatic.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Hmmm. I don't know a whole lot about the mechanics of the human eye, but I

believe the one thing that would take anyone out of the running for sight

restoration is a damaged or dead optic nerve. When you say " nerve damage " it's

hard to say what happened to you. As I just said, there is your optic nerve, so

I don't know. Whatever happened to you sounds traumatic.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

thanks dave. i realize this is a difficult question but i just had to ask. karen

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

thanks dave. i realize this is a difficult question but i just had to ask. karen

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

I'm afraid I wasn't much help. Most of the sight restoration research appears to

involve the back of the eye, or the retina, or in some cases, the front of the

eye, or the cornea. I've never heard of blindness occurring under the conditions

you mentioned happened to you. I suspect your case is non-typical. At any rate,

it doesn't appear there are any real break-throughs any time soon for any of us.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

I'm afraid I wasn't much help. Most of the sight restoration research appears to

involve the back of the eye, or the retina, or in some cases, the front of the

eye, or the cornea. I've never heard of blindness occurring under the conditions

you mentioned happened to you. I suspect your case is non-typical. At any rate,

it doesn't appear there are any real break-throughs any time soon for any of us.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

I'm afraid you are right Dave. I had several clients when I was

working who went blind after a severe illness or surgery. It is usually

caused from lack of oxygen to the eye and brain and destroys the nerve

endings permanently. It's really tough when you go into a hospital with

sight and come out with none.

Is that how your diabetes was diagnosed ?

_____

From: blind-diabetics

[mailto:blind-diabetics ] On Behalf Of dave Bond

Sent: Friday, April 08, 2011 12:29 PM

To: blind-diabetics

Subject: Re: Lab-grown retina ups transplant hopes

I'm afraid I wasn't much help. Most of the sight restoration research

appears to involve the back of the eye, or the retina, or in some cases, the

front of the eye, or the cornea. I've never heard of blindness occurring

under the conditions you mentioned happened to you. I suspect your case is

non-typical. At any rate, it doesn't appear there are any real

break-throughs any time soon for any of us.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

i was found to have type one diabetes forty three years ago. karen

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

i was found to have type one diabetes forty three years ago. karen

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

i was found to have type one diabetes forty three years ago. karen

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

, we're almost the same diabetic age! I was 11. I'm now 55.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

, we're almost the same diabetic age! I was 11. I'm now 55.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

, we're almost the same diabetic age! I was 11. I'm now 55.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Dave we are twins, smile. I found that diabetes never stopped me from doing what

I wanted to do in life. I loved my work, now being retired I still manage to

fill my days with productive challenges. there is not many dull moments. I read

a story about a couple that gave birth to a baby with no eyes, dwarfed arms and

legs. the story ended with the boy in second year of college, looking forward to

the next three years of education. he was a fantastic person on the piano,

wanted to continue to travel and be a motivational speaker. all plus was going

on in his live because it all was about family support. if I ever have a bad day

I will think of this young person always being so positive and productive. my

hat is off to him. did you work or are you still working. I think the hardest

thing about being totally blind is mobility. I do the treadmill because I was an

avid walker and realize how important exercise is for good health.

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

Dave we are twins, smile. I found that diabetes never stopped me from doing what

I wanted to do in life. I loved my work, now being retired I still manage to

fill my days with productive challenges. there is not many dull moments. I read

a story about a couple that gave birth to a baby with no eyes, dwarfed arms and

legs. the story ended with the boy in second year of college, looking forward to

the next three years of education. he was a fantastic person on the piano,

wanted to continue to travel and be a motivational speaker. all plus was going

on in his live because it all was about family support. if I ever have a bad day

I will think of this young person always being so positive and productive. my

hat is off to him. did you work or are you still working. I think the hardest

thing about being totally blind is mobility. I do the treadmill because I was an

avid walker and realize how important exercise is for good health.

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.

[Guest guest]

I returned to college and got a BS (after 3 years) as part of rehabilitation. I

landed a job before I graduated (in an unrelated field), but that job ended in

2000. I've been self-unemployed since then! I spend my days writing

inspirational fiction. Not much money in this field, but it keeps my mind active

and is a goal to strive toward. I don't exercise like I probably should, but I

have good circulation and my diabetes is very well managed.

Dave

" ...In this world you will have trouble. But take heart! I have overcome the

world. " [ 16:33]

Lab-grown retina ups transplant hopes

Lab-grown retina ups transplant hopes

Alleyne

Edmonton Journal , Apr. 7, 2011

Eye transplants to cure blindness are a step closer after Japanese

scientists managed to " grow " a retina in the laboratory for the first time.

Researchers were amazed when stem cells in a test tube organized themselves

spontaneously into a complex structure that resembled the developing

embryonic eye. The development could lead to whole retinas being cultured

and then transplanted, restoring sight in the blind and visually impaired.

The team from the Institute of Physical and Chemical Research in Japan,

first cultivated embryonic stem cells in a test tube and then added proteins

to trigger their development. They hoped that they would form a recognizable

organ but were stunned when over 10 days they clustered together and began

to grow the " optical cup " of a retina.

Tests showed that the cells were functioning normally and were capable of

communicating with each other. The research was done on mouse eyes, but

there is no reason why a similar technique would not work on humans, said

the experts.

They hope within 10 years to be able to start clinical trials on retina

implants.

" This is an absolutely stunning achievement, " said Professor Robin Ali, an

ophthalmologist at University College London. " It is a landmark not just for

the retina but for regenerative medicine as a whole. "

The retina is the part of the eye where nerve cells convert light into

electrical and chemical signals that are sent to the brain down the optic

nerve.

If it is not working, then the eye is useless.

Yoshiki Sasai, the lead author of the study, said: " What we've been able to

do in this study is resolve a nearly century-old problem in embryology, by

showing that retinal precursors have the inherent ability to give rise to

the complex structure of the optic cup. "

The research was published in the journal Nature.