Re: transdermal glutathione

[Guest guest]

Hi ,

Do coffee enemas deplete glutathione? I was under the impression that

they increase it and so that's why I was doing them. Somewhere I read

that they increase it more than any gluthatione precursors (ie NAC)and

more than the glutathione supplement itself. I don't know

though...seems everything is a contradiction of what I've read before!

Watermelon and asparagus as well as some other fruits and veggies are

high in glutathione. Some women I've talked to have done the

watermelon flush where they eat only watermelon for 3 days to detox and

increase glutathione.

Love, Ph

--- In , " mersan1998 " <mersan1998@...>

wrote:

>

> I was reading in one of Patty's post how important glutathione is and

> that coffee enemas will deplete it. I think that's great Patty

> mentioned that as I've never seen it mentioned before when reading

> about coffee enemas.

>

> I was wondering if anyone has tried transdermal glutathione ? I

tried

> it once and it helped my fat digestion immediately. I stopped due to

$

> but Ithink I'll buy some glutathione and mix it with coconut oil and

> apply it myself.

>

>

>

[Guest guest]

Hi PH and ,

Coffee enemas do increase the activity of the gluthathione S

transferase system, seven-fold; however, doing enemas without the

support of juicing can have a depleting effect on nutrients.

Glutathione is absolutely vital in the binding of free radicals and

detoxing, so you want to make sure you are not doing enemas without

providing support, especially for those precursors that are necessary

for glutathione, such as NAC and Alpha Lipoic Acid.

I hope that helps a bit....here is a great article on liver

detoxification that discusses the detox pathways:

http://www.getalife.net.au/mag/lstress2_html

Liver Stress and How to Correct it - Part 2

In the previous article we explored the central role of the liver in

health and the broad range of problems that manifest when the liver

becomes over-taxed including digestive, hormonal, emotional and energy

imbalances, muscle pain and spasms, heart disease and insomnia.

Alleviating liver stress is simple with only three criteria for

successful treatment:

reduce its burden

replenish its stores

support its detoxification

REDUCING THE BURDEN

Underpinning most patterns of liver disharmony is stagnation and heat

in that organ. The liver carries the greatest metabolic burden of the

body; its greatest burden is the processing of the input (diet) and

the output (detoxification), and when overtaxed we see the knock-on

effect on the rest of the body of toxic build-up and nutrient

deficiency – both of which will ultimately erode tissue integrity,

defense and vitality. In short, the health of your liver reflects and

governs your overall health. So the top priority is reduction of the

dietary and toxic burden. When treating the liver, the success of

treatment lies in reducing the input, rather than applying remedies.

Simply by giving the liver a rest allows the respite required for

healing. If you follow the steps below you may be amazed at your own

healing potential.

Remove factors which " heat " the liver

Any factors, including emotional, dietary and chemical, which cause

the liver to work harder will create further heat and stagnation.

Emotional upsets (anger, frustration) and most drugs (including the

contraceptive pill and hormone replacement) will exacerbate patterns

of liver disharmony. However, when resolving liver stress the most

immediate impact comes from dietary manipulation – the removal of

foods, chemicals and stimulants that create excess heat:

High fat (including oils, nuts and seeds) and fried foods, high

protein foods, meat, alcohol, processed foods

Stimulants: caffeine containing beverages, chocolate, sugar,

additives, hot spices such as dried ginger, chillies, cayenne,

horseradish, mustard, raw garlic

Chemicals in the workplace and in our food, food additives such as

preservatives (especially phosphates) and colourings

Over-eating!!

Remove potential allergens and " indigestible " foods

If you have food allergies or intolerances, it is best to remove the

offending foods. When the digestion fails to break down these foods

adequately, they pass to the liver, which then carries the additional

burden of having to grab and eliminate the partially digested

" foreign " food before it reaches the system. It is only when the liver

cannot fulfil this task that these allergens escape into the system

causing allergic reactions or sensitivities. The " damp " foods such as

dairy, wheat, yeast, bananas, and rich foods, also should be

eliminated when the digestion is deficient.

REPLENISHING THE TISSUES

An easily digested diet, rich in living nutrients is not only going to

reduce the burden on the digestive tract and liver, but also supply

copious amounts of minerals, vitamins and enzymes required for

healing. If you suffer bloating, acid reflux/indigestion, irritable

bowel, or allergy/intolerance, then you would be advised to take

additional care and make sure that you do not eat too many raw or

fibre-rich foods. These require a strong digestive capacity to break

down and access the nutrients. Slow-cooked foods, vegetable

casseroles, soups and the use of defatted chicken stock will assist

the digestion and ensure absorption of nutrients. Remember, a diet

that is indigestible, by default leads to nutrient deficiency.

Correct food preparation is vital. Foods exposed to processing

techniques such as high pressure, temperature (frying, pressure

cooking) and microwaves, will structurally change to the point where

they become " non foods " (the body doesn't recognize them), and at

worst render them toxic. Carbohydrates, when fried (as in potato

chips, fried rice) turn to plastic (acrylamides), and heated fats

convert to their trans form (trans-fatty acids). These foods increase

liver stress and deepen nutritional deficiencies.

The seeds - whole grains, legumes and nuts - need additional

attention. They are rich in anti-nutrients, which is why those

following a vegetarian diet over a long period can become

nutritionally depleted. Soy products are probably the biggest culprit

– being high in phytic acid and anti-trypsin factors. All seeds

contain enzyme inhibitors which stop them from sprouting until

conditions prevail. These inhibitors will also oppose your own

digestive enzymes and prevent digestion. Soaking these foods for 12

hours, then semi-germinating for 12 hours (rinse, drain and place a

damp cloth over) before cooking as normal will eliminate the

anti-nutrients. Soaking neutralizes the phytates (which bind and

deplete the system of iron, zinc, calcium and magnesium) and

semi-germinating deactivates the enzyme inhibitors. Similarly, the

fermentation process in sour dough leavening neutralizes

anti-nutrients in the grain and therefore yields a higher nutrient,

more easily digested bread than the yeast proved varieties. Beware of

wheat bran and large quantities of wheat germ – they are both high in

the anti-nutrients.

Juicing. The healing potential of the diet is found in its raw

content, which contains living nutrients and enzymes. As soon as food

is cooked, it is " dead, " and a dead food diet will not heal the body.

Food can indeed be a medicine when taken raw, unprocessed and

unpasteurized. The time is long gone when we used the raw milk and the

raw liver cure – yes, these programs enjoyed remarkable success.

However, most people have deficient digestions, and a raw food diet of

fruits, nuts and vegetables is guaranteed to make you sicker and more

deficient. This is where vegetable juicing comes in. We can get

quantity, quality and digestibility all in one shot. Good juicing

methods will produce fibre-free juice, with enzymes intact. These

should be taken immediately upon preparation – remember bottled juices

are pasteurized and dead.

Protein. Protein, like fats, burdens the liver, but we do need to

ensure adequate protein for healing. Vegetables will provide good

quality protein but in very small amounts. When we juice it becomes

easier to increase the volume. You will still need to make good your

protein requirements, but remember– a little goes as long way. The

inclusion of small quantities of legumes and whole grains will be

sufficient to balance the protein equation, but if you have blood

deficiency then it is advisable to take some fish, and if you suffer

anaemia (iron and B12 deficiency) – then organic liver is the best

remedy. Under these circumstances, small servings of animal protein at

five meals of the week should suffice.

SO YOUR DAILY DIET MAY LOOK SOMETHING LIKE THIS:

Breakfast

Porridge with stewed fruit (dried or fresh).

Lunch

Baked potato/potato salad with skimmed milk yoghurt* and flaxseed oil

(the only oil allowed), or brown rice salad with fresh vegetable

salad, and cooked vegetables/soup (soups can be made with the

legumes); spreads/dips using vegetables/legumes. A slice of sprouted

rye bread or a sough dough rye bread – salt-free.

Evening meal

Similar to lunch. My book " Get a Life, " although not so strict an

approach has many adaptable recipes. Have plenty of vegetables/salads

with your meal. Include some fish or liver if indicated.

In addition, you would be looking at taking a minimum of one litre of

mixed apple and vegetable juice daily.

* Dairy in the form of cultured yoghurt is allowed only in small

amounts. Omit in allergy or intolerance.

SUPPORTING DETOXIFICATION

The rate of toxin removal from the liver determines the individual's

susceptibility to toxic overload and hence the development of chronic

disease.

It's essential that the blood is cleansed of toxins on a continuous

basis. Your entire blood volume passes through the liver every 3

minutes during which time toxins are removed and detoxified for safe

elimination. If this fails to occur, toxins and free radicals (very

aggressive and destructive molecules) will be dumped back into the

circulation causing widespread damage in the tissues and organs,

including the brain. These problems occur when the liver has been

subject to prolonged toxic overload, or if there is a reduction in the

capacity of its detoxification pathways.

Detoxification essentially means converting a toxin to a non-toxic,

soluble form that can be safely eliminated either by the liver or the

kidneys. The liver is the principle organ for these reactions and has

several pathways to deal with each family of toxins. There are two

phases to consider:

Phase 1

Most toxins enter the first phase (P450 enzyme system) which converts

the incoming toxins to intermediate metabolites – not only are these

more toxic than their precursors but a lot of free radicals are

generated in the process. All chemicals (dioxins, residual pesticides,

exhaust and paint fumes), caffeine, alcohol, dietary protein and

steroid hormones (including the pill and HRT, cortisone) will

stimulate phase 1 activity and it is vitally important that the second

phase (whose job it is to grab and neutralize these agents before they

do any damage) keeps pace with phase 1 activity.

Toxins------> intermediate metabolites---> non-toxic/soluble compounds

Phase 1 (very toxic) Phase 2

P450 conjugation pathways

Some people are " pathological detoxifiers " meaning that their phase 1

is more active than their phase 2. This will lead to a build-up of

intermediate toxins causing:

liver damage

chemical sensitivities

food sensitivities (specifically caffeine, alcohol, cheese,

chocolate, yeasts)

general fatigue and drowsiness – caused by the effect of

accumulating intermediate aldehydes which have a similar action to

tranquillizers.

Obviously, under these circumstances we need to reduce exposure to the

stimulants of phase 1 and activate phase 2.

Phase 2

Phase 2 activity involves binding the intermediate metabolites with

compounds that effectively neutralises their activity and makes them

water-soluble. This is known as the conjugation process. There are

five major conjugation pathways which take up the various families of

chemicals:

sulphation (steroid hormones, paracetamol, drugs, adrenaline,

pesticides etc).

glutathione conjugation – a major pathway (bile acids, food

preservatives, aspirin, chemicals); also responsible for the binding

of all free radicals

acetylation (drugs, toxic chemicals)

methylation (histamine, food " amines, " adrenaline, chemicals)

glucuronidation (bilirubin, chemical and bacterial toxins, alcohol,

amines)

Nowadays we all run the risk of chemical exposure and overload which

ultimately results in depletion and exhaustion of the liver's

detoxification pathways. Once this occurs our levels of toxicity, and

the tissue damage created by such powerful toxins, take their toll

contributing to the rise in chronic disease and cancer. Studies

performed in the UK (1) have already proved a link between a

deficiency in the sulphation conjugation pathway of patients with

Parkinsons, Motor Neurone Disease and Alzheimer's indicating toxic

stress as a major predisposing factor in degenerative disease of the

nervous system. Similarly, 50% of the general population and 80% of

chemically sensitive people are slow acetylators.

HOW CAN WE SUPPORT OUR LIVERS?

A good supply of natural anti-oxidants (Vitamin C, E, flavonoids) is

going to protect you against oxidative stress in the liver and the

general system. (How much fresh, raw organic fruit and vegetables do

you consume daily?) Equally, food-derived minerals such as zinc,

selenium and magnesium that power some of these detoxification enzymes

systems are also critically important.

Milk Thistle is a unique liver protective herb which protects liver

cells from toxins

Organic sources of sulphur as found in the cruciferous vegetables

(broccoli, cabbage, Brussels sprouts, cauliflower), raw garlic,

onions, leeks, radish and watercress, will support the sulphation

pathway. (Important in your breakdown of oestrogens).

Keep away from heavy metal contamination. Mercury (used widely as a

fungicide on food crops), aluminum (canned foods, deodorants) and lead

will supplant selenium in the anti-oxidant enzyme systems, and in

doing so will paralyze these enzyme systems which normally protect you

from free radical damage and oxidative stress. Once these

fire-fighters are paralyzed, untold free radical damage occurs leading

to the destruction of tissues and chronic disease (particularly in the

nervous system and brain). Fresh vegetable juices will not only

provide you with your anti-oxidants but enough pectin to chelate these

heavy metals and clear them from your system.

Kombucha tea supports the glucuronidation pathway. An interesting

bit of research reveals that the risk of cancer was negligible in

Russian communities exposed to radio-active fall-out who consumed

Kombucha tea on a regular basis.

Dandelion root and turmeric are both cholagogues – stimulate the

flow of bile.

Go organic - be preservative and chemical free in your food and

environment. Removal of the source of the problem has to be the

first-line option!

If seriously detoxifying then consider the coffee enema

The coffee enema

The coffee enema goes back a long way. There's been much research

since it was used as the main treatment for pain relief in wounded

German soldiers during both the wars. Various scientific studies have

shown that coffee, when administered rectally is taken up by the

mesenteric vein and delivered straight to the liver where specific

active ingredients of the coffee have a profound effect on the

stimulation of the liver; coffee taken orally does not have this

effect. The various compounds in coffee not only increase the flow of

toxic bile and its flushing into the gastrointestinal tract for

elimination, but also increase the activity of the gluthathione S

transferase system, seven-fold. We have seen that this system is the

major phase 2 detoxification pathway and scavenger of free radicals.

So the coffee enema is both protective against liver damage, and also

enables the speedy elimination of toxins.

Dr. Max Gerson was the first physician to use it extensively in his

cancer therapy as the most effective method for facilitating toxin

removal by the liver. On his detoxification therapy, he found that the

liver of the cancer patient was unable to cope with the onslaught of

toxins released from the tissues, and that patients would deteriorate

faster on the therapy than from the disease itself. More recently it

was used as part of a dietary therapy protocol in a six year

comparative study on cancer patients in Austria (2) to determine its

benefits with regard to the basic disease process and survival time.

It was found that patients on the treatment were in better condition,

had less complications, and showed better toleration of radiation and

chemotherapy – so much so that one group could tolerate the highly

toxic drug, alpha-interferon, at high doses with complete

normalization of liver function. With regard to the liver protective

effect of the coffee enema, the report recommends that the

pharmaceutical industry continue these investigations in order to

" make a highly effective drug for protecting the liver " – as the

administration of enemas was too awkward!! Not so!

If you are sensitive to foods and chemicals, or if you have had

prolonged exposure to chemicals – then you will probably be toxic, the

liver will be struggling and will need all the additional support it

can get. If you are toxic and decide to do a detoxification program

that includes vegetable juices, you would be well-advised to consider

the steps above, but most importantly be ready to use your enema kit

when the toxins start flowing.

1. , A.C., ton, G.B., et al., " Hereditary variation of

liver enzymes involved with detoxification and neurodegenerative

diseases. " Journal of Inherited Metabolic Disorders 1991, Vol. 14: pp

431-435

2. Experiences with the Use of Dietary therapy in Surgical Oncology: P

Lechner, I. Kronberger; Oncological Outpatient Departments, Graz

Austria, 1990

> >

> > I was reading in one of Patty's post how important glutathione is and

> > that coffee enemas will deplete it. I think that's great Patty

> > mentioned that as I've never seen it mentioned before when reading

> > about coffee enemas.

> >

> > I was wondering if anyone has tried transdermal glutathione ? I

> tried

> > it once and it helped my fat digestion immediately. I stopped due to

> $

> > but Ithink I'll buy some glutathione and mix it with coconut oil and

> > apply it myself.

> >

> >

> >

>

[Guest guest]

to be honest we got nothing from the td or the capsules, but did see some

effects from the essential gsh liquid from wellness.

MATT O

From: jrussell82002 <jrussell8@...>

Subject: Transdermal glutathione

Date: Monday, June 22, 2009, 4:19 PM

About to begin using trasndermal glutathione and I was wondering if anyone

out there could share some experiences about what to look for, good or bad.

Thanks