Garlic and fatigue...maybe a potent anti-fatigue agent.....

[Guest guest]

http://inutritionals.com/healthy-living/nutrition-and-supplements/kyolic-garlic-fights-fatigue

One of the most common complaints voiced by patients visiting physicians is simply that their "get up and go, got up and went." Perhaps as a consequence of our very stressful society coupled with the declining quality of our food sources, fatigue now seems to be an almost ubiquitous complaint of patients seen in a general medical practice setting.

These days, a wide variety of nutritional supplements are being promoted to help alleviate fatigue. Unfortunately, the claims made by the producers of many of these products are often not supported by any meaningful scientific research. Clearly, when specific claims are made about a nutritional supplement, it is important that these claims be substantiated.

In an article entitled "Anti-Fatigue Effect of Aged Garlic Extract in Athletic Club Students," researchers at Japan's prestigious Nihon University School of Medicine evaluated the effectiveness of aged garlic extract (Kyolic Garlic) in reducing fatigue in a group of 20 healthy students tested during intense physical training. The study evaluated both subjective and objective parameters. Subjective symptoms included drowsiness, weariness, difficulty in concentration, and several "body conditions" including headache, shortness of breath, and muscle pain. Objective measurements included evaluation of pulse, weight, blood pressure, muscle strength, reflex function, and several laboratory studies.

The results of this study were compelling. Virtually across the board subjective complaints were markedly reduced toward the end of the trial in the group receiving Kyolic Garlic, with the most significant results noted in the evaluations of drowsiness and weariness. Further, objective measurements also demonstrated a significant difference when comparing the group receiving the Garlic Extract versus that which did not. In the group taking Kyolic, reflexes seemed to improve during the course of the study as did laboratory studies measuring liver function.

This study confirms the usefulness of Kyolic Garlic in reducing several parameters of fatigue. As the study reports, "Results of the independently designed subjective symptoms test showed that complaints such as weary body and weak legs decreased with administration of aged garlic extract and disappeared by the end of the study. The results of the objective fatigue test showed improvement of physical functions."

Kyolic Garlic is a very important nutritional supplement not only because of its well substantiated role in reducing fatigue, but also because of its effectiveness in reducing cholesterol, improving glucose tolerance, and its ability to improve liver function and prevent liver cell damage. For more information on Kyolic Garlic, contact Wakunaga of America at (800) 421-2998.

http://cat.inist.fr/?aModele=afficheN & cpsidt=17880642

Titre du document / Document title

Aged garlic extract ameliorates physical fatigueAuteur(s) / Author(s)

MORIHARA Naoaki ; USHIJIMA Mitsuyasu ; KASHIMOTO Naoki ; SUMIOKA Isao ; NISHIHAMA Takeshi ; HAYAMA Minoru ; TAKEDA Hidekatsu ; Résumé / Abstract

Aged garlic extract (AGE) has recentlyreceived attention as a potent anti-fatigue agent. The principal aim ofthis study was to elucidate the mechanism responsible for theameliorating effect of AGE on physical fatigue in rats caused byrepeated endurance exercise on a mechanical treadmill apparatus. Ratswere subjected to endurance exercise 5 times per week for 4 weeks. AGEat a dosage of 2.86 g/kg was administrated to rats 30 min before everyexercise. Succinate dehydrogenase (SDH) activity in the gastrocnemiusand soleus muscles and superoxide dismutase (SOD) activity, nitricoxide (NO) metabolites, and lactic acid concentration in plasma wereevaluated as biomarkers of physical fatigue. SDH activity was increased2-4-fold by repeated endurance exercise in comparison with unexercised(intact) rats, and AGE further up-regulated this activity by 40%. SODactivity was increased 5-fold, whereas AGE maintained it at a levelequivalent to that in intact rats. Levels of NO metabolites wereslightly decreased, whereas AGE enhanced them 2-fold. Lactic acidconcentration was not changed in any of the groups. These resultsindicate that AGE may facilitate the turnover of aerobic glucosemetabolism, attenuate oxidative stress, and promote oxygen supply basedon vasodilation, suggesting that AGE ameliorates the variousimpairments associated with physical fatigue.Revue / Journal Title

Biological & pharmaceutical bulletin ISSN 0918-6158 Source / Source

2006, vol. 29, no5, pp. 962-966 [5 page(s) (article)]Langue / Language

Anglais

Editeur / Publisher

Maruzen, Tokyo, JAPON (1993) (Revue)

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[Guest guest]

Kyolic has an excellent reputation...one of which is that it does not

make you stink!

(Of course, raw garlic does.)

Patty

>

>

>

http://inutritionals.com/healthy-living/nutrition-and-supplements/kyolic-garlic-\

fights-fatigue

> One of the most common complaints voiced by patients visiting

physicians is

> simply that their " get up and go, got up and went. " Perhaps as a

consequence of

> our very stressful society coupled with the declining quality of our

food

> sources, fatigue now seems to be an almost ubiquitous complaint

of patients

> seen in a general medical practice setting.

>

> These days, a wide variety of nutritional supplements are being

promoted

> to help alleviate fatigue. Unfortunately, the claims made by the

producers

> of many of these products are often not supported by any meaningful

> scientific research. Clearly, when specific claims are made about a

nutritional

> supplement, it is important that these claims be substantiated.

>

> In an article entitled " Anti-Fatigue Effect of Aged Garlic

Extract in

> Athletic Club Students, " researchers at Japan's prestigious Nihon

> University School of Medicine evaluated the effectiveness of aged

garlic extract

> (Kyolic Garlic) in reducing fatigue in a group of 20 healthy

students tested

> during intense physical training. The study evaluated both

subjective and objective

> parameters. Subjective symptoms included drowsiness, weariness,

> difficulty in concentration, and several " body conditions "

including headache,

> shortness of breath, and muscle pain. Objective measurements

included

> evaluation of pulse, weight, blood pressure, muscle strength,

reflex function, and

> several laboratory studies.

>

> The results of this study were compelling. Virtually across the

board

> subjective complaints were markedly reduced toward the end of the

trial in the

> group receiving Kyolic Garlic, with the most significant results

noted in the

> evaluations of drowsiness and weariness. Further, objective

measurements

> also demonstrated a significant difference when comparing the

group receiving

> the Garlic Extract versus that which did not. In the group taking

Kyolic,

> reflexes seemed to improve during the course of the study as did

laboratory

> studies measuring liver function.

>

> This study confirms the usefulness of Kyolic Garlic in reducing

several

> parameters of fatigue. As the study reports, " Results of the

independently

> designed subjective symptoms test showed that complaints such as

weary body

> and weak legs decreased with administration of aged garlic extract

and

> disappeared by the end of the study. The results of the objective

fatigue test

> showed improvement of physical functions. "

>

> Kyolic Garlic is a very important nutritional supplement not

only because

> of its well substantiated role in reducing fatigue, but also

because of its

> effectiveness in reducing cholesterol, improving glucose

tolerance, and its

> ability to improve liver function and prevent liver cell damage.

For more

> information on Kyolic Garlic, contact Wakunaga of America at (800)

421-2998.

>

>

> http://cat.inist.fr/?aModele=afficheN & cpsidt=17880642

> Titre du document / Document title

>

> Aged garlic extract ameliorates physical fatigueAuteur(s) / Author(s)

>

> MORIHARA Naoaki ; USHIJIMA Mitsuyasu ; KASHIMOTO Naoki ; SUMIOKA Isao ;

> NISHIHAMA Takeshi ; HAYAMA Minoru ; TAKEDA Hidekatsu ; Résumé / Abstract

>

> Aged garlic extract (AGE) has recentlyreceived attention as a potent

> anti-fatigue agent. The principal aim ofthis study was to elucidate

the mechanism

> responsible for theameliorating effect of AGE on physical fatigue in

rats caused

> byrepeated endurance exercise on a mechanical treadmill apparatus.

Ratswere

> subjected to endurance exercise 5 times per week for 4 weeks. AGEat

a dosage of

> 2.86 g/kg was administrated to rats 30 min before everyexercise.

Succinate

> dehydrogenase (SDH) activity in the gastrocnemiusand soleus muscles

and superoxide

> dismutase (SOD) activity, nitricoxide (NO) metabolites, and lactic acid

> concentration in plasma wereevaluated as biomarkers of physical

fatigue. SDH

> activity was increased2-4-fold by repeated endurance exercise in

comparison with

> unexercised(intact) rats, and AGE further up-regulated this activity

by 40%.

> SODactivity was increased 5-fold, whereas AGE maintained it at a

levelequivalent

> to that in intact rats. Levels of NO metabolites wereslightly

decreased,

> whereas AGE enhanced them 2-fold. Lactic acidconcentration was not

changed in any of

> the groups. These resultsindicate that AGE may facilitate the

turnover of

> aerobic glucosemetabolism, attenuate oxidative stress, and promote

oxygen supply

> basedon vasodilation, suggesting that AGE ameliorates the

variousimpairments

> associated with physical fatigue.Revue / Journal Title

>

> Biological & pharmaceutical bulletin

ISSN

> 0918-6158 Source / Source

>

> 2006, vol. 29, no5, pp. 962-966 [5 page(s) (article)]Langue / Language

>

> Anglais

> Editeur / Publisher

>

> Maruzen, Tokyo, JAPON (1993) (Revue)

>

>

>

>

>

>

>

>

>

>

>

> **************

> New MapQuest Local shows what's happening at your destination.

> Dining, Movies, Events, News & amp; more. Try it out!

>

> (http://local.mapquest.com/?ncid=emlcntnew00000001)

>