Re: antihistamines and anti-inflammatories

[Guest guest]

Hi,

I take Ibuprofen on a regular basis, for (endometriosis) pain. I think it

does help the redness factor of rosacea.

Cyd

antihistamines and anti-inflammatories

> Has anyone tried taking an antihistamine such as chlorpheniramine or

> an anti-inflammatory like ibuprofen for the treatment of rosacea? If

> so, did it help at all?

>

>

>

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[Guest guest]

In a message dated 4/20/00 4:11:02 PM Eastern Daylight Time

judyjudyjudy2000@... writes:

>Has anyone tried taking an antihistamine such as chlorpheniramine or

an anti-inflammatory like ibuprofen for the treatment of rosacea? If

so, did it help at all?

I take Atarax (antihistamine) and Celebrex (anti-inflammatory). Both

help.....

Bill

[Guest guest]

<<Has anyone tried taking an antihistamine such as chlorpheniramine or

an anti-inflammatory like ibuprofen for the treatment of rosacea? If

so, did it help at all?>>

I was given Zyrtec by a dermatologist who told me that it reduced flushing

symptoms for 50% of his patients. Didn't work for me. It's a good

antihistamine though.

I find that aspirin+cimetidine and lots of cold water help with the

flushing. I take a cimetidine (generic Tagamet), drink a glass of water,

take a couple of buffered aspirin, drink more water, take two more aspirin a

few minutes later if the flushing is bad, along with plenty of ice cold

water.

Jim Clary, Dallas TX

antihistamines and anti-inflammatories

[Guest guest]

I've found that after a few days of taking an anti-inflammatory pain

killer (it wouldn't do any good to tell you the name- its not found

in North America) that my cea is significantly better if it had

been flaring before.

Also, my last best remission was during the time when I was taking

antihistamines for the flu and subsequently a sinus infection.

> Has anyone tried taking an antihistamine such as chlorpheniramine

or

> an anti-inflammatory like ibuprofen for the treatment of rosacea?

If

> so, did it help at all?

[Guest guest]

> Also, do you know by what mechanism citmetidine works to reduce flushing?

Barry,

In my original message posted in the archives, I mentioned the different

chemical mediators that cause vasodilatation, such as histamine,

prostaglandin, serotonin, bradykinin etc. Cimetidine is a H2 receptor

blocker while chlorpheniramine is a H1 receptor blocker. (Zyrtec & Claritin

are both H1 receptor blockers). Aspirin (together with indomethacin) block

prostaglandin synthetase. Pyridoxine (B6) has prophylactic effect on

flushing caused by certain foods that contain nitrites, sulfites, monosodium

glutamate etc. The original query was from Matija who asked me how she can

reduce facial swelling. In that post, I was attempting to give a regimen

with a list of over-the-counter medications (prescription meds were left out

but obviously they are quite effective) that might help reduce facial

swelling which I theorized as caused by repeated bouts of flushing. Ergo, if

flushing is reduced, so will the swelling. I am gratified that some members

seem to find relief and benefit from this regimen.

Sy M.D.

Sy Skin Care

http://www.lindasy.com

Voice:Toll-free 877-sy (546-3279)

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> antihistamines and anti-inflammatories