Guest guest Posted August 30, 2001 Report Share Posted August 30, 2001 I have never seen anything which states acetaminophen causes pancreatitis or an pancreatic attack. But Acetaminophen in large does hurt the Liver. The Liver and the Pancreas work hand and hand so it makes sense that it could cause problems. If I come across any direct info I will forward it on to you I hope this finds you and yours well Mark E. Armstrong www.top5plus5.com Mark: Intro page, and > > corticosteroids??? > > > > > > > Hi Mark - > > > > > > I've seen a couple posts from you concerning your > > webpage that you > > > were updating, and your most recent asked for > > feedback on your intro > > > page. My question for you is: Who is the > > audience for this website? > > > Is it a place for doctors to get information? or > > a place for people > > > like me who are trying to understand what this > > disease is? Without > > > knowing the intention of the site it's hard to > > give feedback. > > > > > > > > > My other question to Mark or anyone - I saw that > > corticosteroids were > > > listed as a potential cause of pancreatitis - does > > anyone know > > > anything abotu that? I had three shots of > > cortisone in my wrists last > > > fall for carpal tunnel problems and tendonitis. > > Could those shots > > > have caused pancreatitis?? > > > > > > thanks - > > > > > > > > > > > > > > > > > > > Clear DayGoing to show you my Introduction page > > on the new site I am > > > working on. Please let me know what you think. > > > > INTRODUCTION > > > > > > > > Background: Pancreatitis is an inflammatory > > process in which > > > pancreatic enzymes autodigest the gland. > > > > > > > > The gland can sometimes heal without any > > impairment of function or > > > any morphologic changes. This process is known as > > acute pancreatitis. > > > It can recur intermittently, contributing to the > > functional and > > > morphologic loss of the gland. Recurrent attacks > > are referred to as > > > chronic pancreatitis. Both forms of pancreatitis > > are present in the ED > > > with acute clinical findings. > > > > > > > > > > > > Pathophysiology: Because the pancreas is located > > in the > > > retroperitoneal space with no capsule, > > inflammation can spread easily. > > > In acute pancreatitis, parenchymal edema and > > peripancreatic fat > > > necrosis occur first. This process is known as > > acute edematous > > > pancreatitis. > > > > > > > > When necrosis involves the parenchyma, > > accompanied by hemorrhage and > > > dysfunction of the gland, the inflammation evolves > > into hemorrhagic or > > > necrotizing pancreatitis. > > > > > > > > Pseudocysts and pancreatic abscesses can result > > from necrotizing > > > pancreatitis because of enzymes being walled off > > by granulation tissue > > > (ie, pseudocyst formation) or bacterial seeding of > > pancreatic or > > > peripancreatic tissue (ie, pancreatic abscess > > formation). An > > > ultrasound or, preferably, a CT scan can be used > > detect both. > > > > > > > > The inflammatory process can cause systemic > > effects because of the > > > presence of cytokines, such as bradykinins and > > phospholipase A. These > > > cytokines may cause vasodilation, increase in > > vascular permeability, > > > pain, and leukocyte accumulation in the vessel > > walls. Fat necrosis may > > > cause hypocalcemia. Pancreatic B cell injury may > > lead to > > > hyperglycemia. > > > > > > > > > > > > Frequency: > > > > > > > > > > > > a.. In the US: Annual incidence of acute > > pancreatitis is 19.5 per > > > 100,000 population and chronic pancreatitis is 8.3 > > per 100,000 > > > population per year. > > > > Mortality/Morbidity: > > > > > > > > a.. Although acute pancreatitis should be > > noted, chronic > > > pancreatitis has a more severe presentation as > > episodes recur. > > > > a.. Acute respiratory distress syndrome > > (ARDS), acute renal > > > failure, cardiac depression, hemorrhage, and > > hypotensive shock all may > > > be systemic manifestations of acute pancreatitis > > in its most severe > > > form. > > > > Race: Annual incidence of acute pancreatitis in > > Native American > > > persons is 4 per 100,000 population, in white > > persons is 5.7 per > > > 100,000 population, and in black persons is 20.7 > > per 100,000 > > > population. > > > > > > > > Sex: No predilection exists. > > > > > > > > Age: The risk for African American persons aged > > 35-64 years is 10 > > > times higher than for any other group. African > > American persons are at > > > higher risk than white persons in that same age > > group. > > > > > > > > > > > > > > > > Clinical > > > > > > > > History: > > > > > > > > a.. The main presentation of acute > > pancreatitis is epigastric pain > > > or right upper quadrant pain radiating to the back > > > > a.. Nausea and/or vomiting > > > > a.. Fever > > > > a.. Query the patient about recent surgeries > > and invasive > > > procedures (ie, endoscopic retrograde > > cholangiopancreatography) or > > > family history of hypertriglyceridemia. > > > > a.. Patients frequently have a history of > > previous biliary colic > > > and binge alcohol consumption, the major causes of > > acute pancreatitis. > > > > Physical: > > > > > > > > a.. Tachycardia > > > > a.. Tachypnea > > > > a.. Hypotension > > > > a.. Fever > > > > a.. Abdominal tenderness, distension, > > guarding, and rigidity > > > > a.. Mild jaundice > > > > a.. Diminished or absent bowel sounds > > > > a.. Because of contiguous spread of > > inflammation (effusion) from > > > the pancreas, lung auscultation may reveal basilar > > rales, especially > > > in the left lung. > > > > a.. Occasionally, in the extremities, muscular > > spasm may be noted > > > secondary to hypocalcemia. > > > > a.. Severe cases may have a Grey sign > > (ie, bluish > > > discoloration of the flanks) and Cullen sign (ie, > > bluish discoloration > > > of the periumbilical area) caused by the > > retroperitoneal > === message truncated === > > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
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