Re: Ray Peat in his own words/pufa/long w/references

[Guest guest]

--- In @y..., " drmichaelmarasco " <mmarasco@c...>

wrote:

>Coconut oil

> completely abolished the responses to endotoxin. The inhibitory

> effects of

> coconut oil could largely be due to reduced prostaglandin and

> leukotriene

> synthesis.

I probably don't understand this, so could somebody explain to me why

inhibiting response to the endotoxin is good?

Roman

[Guest guest]

Good grief.

Three references:

1. Kelley DS ...

This reference supports the fact that omega-3 fatty acids have anti-

inflammatory properties and can mediate series 2 prostaglandins. This

is a *good* thing.

2. Rabinowitch HD ...

A study of polyunsaturates on bacteria? How about humans or at least

animals?

3. Wan JM ...

A study of a diet high in corn oil vrs. a diet high in coconut oil.

No one on this list would opt for the corn oil diet.

These references don't address the point. No one here is arguing that

excess polyunsatures aren't bad - we're all believers in eating

stable, hard to oxidize animal fat. Rather, we are debating the

merits of a diet of zero polyunsaturates v. a diet with small amounts

of quality polyunsatures like omega-3 fatty acids (which are found

naturally in grassfed animals). The references don't even address

this issue!

Meanwhile, clinical trials show the omega-3 fatty acids result in a

statistically significant reduction in total mortality(1). Avoid

omega-3's at your own risk!

1. Heiner C. Bucher; E. Griffith; Gordon H. Guyatt. Systematic

Review on the Risk and Benefit of Different Cholesterol-Lowering

Interventions. Arteriosclerosis, Thrombosis, and Vascular Biology.

1999;19:187-195

[Guest guest]

Roman,

endotoxin is an insidious substance and what its saying here is the

ingestion of coconut oil prevented the endotoxin from eliciting a

detrimental response from the physiology. It had a protective effect.

DMM

> >Coconut oil

> > completely abolished the responses to endotoxin. The inhibitory

> > effects of

> > coconut oil could largely be due to reduced prostaglandin and

> > leukotriene

> > synthesis.

>

>

> I probably don't understand this, so could somebody explain to me

why

> inhibiting response to the endotoxin is good?

>

> Roman

[Guest guest]

Hi ,

from my conversations with Peat on this topic and this reference in

particular his take is that the anti-inflamatory response is due to

immunosupression much like radiation is used in ringworm and

sinusitis.

I'm just a messenger :-))

DMM

>

> Three references:

>

> 1. Kelley DS ...

>

> This reference supports the fact that omega-3 fatty acids have anti-

> inflammatory properties and can mediate series 2 prostaglandins.

This

> is a *good* thing.

>

[Guest guest]

If I understand correctly the inflamatory response involved in arthritis or

some such thing involves an inappropriate overactivation of the immune

system, so if omega-3's are beneficial as an anti-inflamatory agent, it is

because they suppress the overactivation of the immune systems. In other

words omega-3's contibute to normal healthy functioning of the body instead

of the abnormal, unhealthy response to omega-6 fats.

Peace,

Kris , gardening in northwest Ohio

----- Original Message -----

From: drmichaelmarasco <mmarasco@...>

< >

Sent: Wednesday, March 20, 2002 12:00 PM

Subject: Re: Ray Peat in his own words/pufa/long

w/references

> Hi ,

>

> from my conversations with Peat on this topic and this reference in

> particular his take is that the anti-inflamatory response is due to

> immunosupression much like radiation is used in ringworm and

> sinusitis.

>

[Guest guest]

--- In @y..., " Kris. " <Kris.@a...>

wrote:

> If I understand correctly the inflamatory response involved in

arthritis or

> some such thing involves an inappropriate overactivation of the

immune

> system, so if omega-3's are beneficial as an anti-inflamatory

agent, it is

> because they suppress the overactivation of the immune systems. In

other

> words omega-3's contibute to normal healthy functioning of the body

instead

> of the abnormal, unhealthy response to omega-6 fats.

There is a pretty good article about omega fatty acids on the weston

price website. The omega-6's get a bad rap because they produce pro-

inflammatory prostaglandins, however inflammation plays an important

role in healing. The problem is rather that our omega-3 to omega-6

ratio is out of wack, so our inflammation response is out of wack.