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Re: AP while on Methotrexate and Cyclosporine

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No you do not need to be off methotrexate to go on antibiotics. Matter

of fact sometimes it's good because it will help keep the inflammation down

while waiting for the antibiotics to kick in. So run to your doc and get

Minocin and start taking it ASAP! Welcome to the group. You will get lots of

good advice and stories here. Also go to rheumatic.com for more stories to

hear about other people with yours or similar diseases.

cooky

Hi Everyone, my name is . I was diagnosed with Dermatomyositis about 4

years ago.

After having gotten to the point of not being able to get out of bed without

help twice, I had

been doing okay for about a year and half. The first round was IVIG with

prednisone, that

didn't last very long however, the next round was methotrexate with

cyclosporine, and I

thought that was the winner. I am starting to go back down however, so I

know I am in fact

not better. I came accross the Fairy Lady's story, and was inspired. I am

very enthusiastic to

start on antibiotics, but read that you needed to be off methotrexate for 6

weeks. I was

wondering if anyone has taken antibiotics at the same time as methotrexate,

or if I should

wait until I'm off methotrexate again. I wish I would have started this 5

months ago, when

my doctor took me off methotrexate. If anyone can help, I would greatly

appreciate it.

__

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>

> Hi Everyone, my name is . I was diagnosed with

Dermatomyositis about 4 years ago.

> After having gotten to the point of not being able to get out of

bed without help twice, I had

> been doing okay for about a year and half. The first round was

IVIG with prednisone, that

> didn't last very long however, the next round was methotrexate with

cyclosporine, and I

> thought that was the winner. I am starting to go back down

however, so I know I am in fact

> not better. I came accross the Fairy Lady's story, and was

inspired. I am very enthusiastic to

> start on antibiotics, but read that you needed to be off

methotrexate for 6 weeks. I was

> wondering if anyone has taken antibiotics at the same time as

methotrexate, or if I should

> wait until I'm off methotrexate again. I wish I would have started

this 5 months ago, when

> my doctor took me off methotrexate. If anyone can help, I would

greatly appreciate it.

> Thanks,

>

>

>

I was only on Methotrexate for 3 months when I decided to go the AP

route. All my CBC and liver functions were in a normal range, so I

stopped MTX on Tues and started Minocycline on the Friday(w/o

6/1/2008) of the same week. I have read of some people who are on

both MTX and Minocycline, without liver problems. I have PSORIATIC

ARTHRITIS and have had all symtoms inprove on AP. I am taking 100mg

Minocycline twice daily, 2.5mg Prednisone and 50mg of Diclofenac and

am pain free. The PSA attack started in dec, 2007. I caught it quick

enough that I do not have joint damage. It had attacked both hips,

shoulders and my whole spinal column. Have lost some range of motion,

but am pain free. Had not had any herxing to date, but only 3 weeks

into AP

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Hi, !

Sally in Little Rock here.

I've been doing AP (100 mg 2x day minocycline and 500 mg Zithromax, 2x wkly,

then down to 100 mg 3x wk of mino and 500 mg 1x wk of Zithro) and methotrexate

-started at 10 mg wkly, up to 20mg wkly, since Sept '06.

Ironically, I decided at the beginning of this year to stop full time AP and

ended up with a sinus infection that I cannot get rid of!! I've had 2-3 while

on metho and AP but cleared up pretty easily by getting off metho and stronger,

infection specific antibiotics.

Sooo, now I'm going back to my full time AP and may have to go back for another

round of Biaxin (antibiotic for sinus infections) before starting the metho

again.

Also, was taking steroids (able to cut back to 5-10mg daily while on metho and

400 mg Celebrex) and still am taking steroids.

So, yes, I would HIGHLY recommend AP with metho as I feel the AP kept chronic

infection at bay for me.

I think I have Lyme's (Dx by 2 good rheumies as Reactive Arthritis or Reiter's

Syndrome-means my RA was caused by infection and I did get a terrible looking

bite on my thigh in '92

and went from being sooo healthy and athletic to a middle aged cripple-BUMMER!!)

Good luck to you!

Sally in Little Rock

From: Albornoz

Sent: Wednesday, June 25, 2008 11:59 AM

rheumatic

Subject: rheumatic AP while on Methotrexate and Cyclosporine

Hi Everyone, my name is . I was diagnosed with Dermatomyositis about 4

years ago.

After having gotten to the point of not being able to get out of bed without

help twice, I had

been doing okay for about a year and half. The first round was IVIG with

prednisone, that

didn't last very long however, the next round was methotrexate with

cyclosporine, and I

thought that was the winner. I am starting to go back down however, so I know I

am in fact

not better. I came accross the Fairy Lady's story, and was inspired. I am very

enthusiastic to

start on antibiotics, but read that you needed to be off methotrexate for 6

weeks. I was

wondering if anyone has taken antibiotics at the same time as methotrexate, or

if I should

wait until I'm off methotrexate again. I wish I would have started this 5 months

ago, when

my doctor took me off methotrexate. If anyone can help, I would greatly

appreciate it.

Thanks,

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