Guest guest Posted April 18, 2000 Report Share Posted April 18, 2000 Kathleen, When I first started on metho, I was taking it in the mornings and fighting being sick all day. My Doctors feel its fine to take it just before bed time. That way I sleep through the yuks. But it is really important that you take it on the same day each week. You may want to run this by your doctors first in the event you are on other meds at night. They may not be compatible. Metho. takes 24 hrs. to clear out of your liver and get to the other places it needs to be. Also don't drink grapefruit juice until you are no longer on metho. Something about grapefruit that holds it in the liver longer. Love R. Quote Link to comment Share on other sites More sharing options...
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