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Re: AP minocycline dose

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Hi Amy,

Doctor Brown's protocol calls for MWF 100mgm 2 times a day. The reason for

MWF is to prevent resistance and because mycos do not produce offspring

(haha) everyday so you are wasting medicine. If you are improving on this

dosage that is great and you should stay on it. The less medicine you take

to get well the better. If progress stops you can increase to twice a day

for a while to " kick start " it again. Good luck.

cooky

Subject: rheumatic AP minocycline dose

Thanks for the recent postings on doses of minocycline that lead to

remission. I have been on 100mg mino MWF for 4 months and have improved and

was just wondering if I should start taking it every day. My General

Practitioner is willing to prescribe mino for me, but doesn't know the

protocol. I am now going to switch to 100mg twice a day, every other day,

thanks to Marla's (?) post. I look forward to joining the Remission Club!

Amy

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What about those with scleroderma, I thought they were supposed to take

everyday 2x / day?

From: rheumatic [mailto:rheumatic ] On Behalf

Of Cooky Stonkey

Sent: Tuesday, January 11, 2011 12:23 PM

rheumatic

Subject: RE: rheumatic AP minocycline dose

Hi Amy,

Doctor Brown's protocol calls for MWF 100mgm 2 times a day. The reason for

MWF is to prevent resistance and because mycos do not produce offspring

(haha) everyday so you are wasting medicine. If you are improving on this

dosage that is great and you should stay on it. The less medicine you take

to get well the better. If progress stops you can increase to twice a day

for a while to " kick start " it again. Good luck.

cooky

Subject: rheumatic AP minocycline dose

Thanks for the recent postings on doses of minocycline that lead to

remission. I have been on 100mg mino MWF for 4 months and have improved and

was just wondering if I should start taking it every day. My General

Practitioner is willing to prescribe mino for me, but doesn't know the

protocol. I am now going to switch to 100mg twice a day, every other day,

thanks to Marla's (?) post. I look forward to joining the Remission Club!

Amy

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All I know about scleraderma treatment is that it is better if you do IV's.

I'm sorry I have RA and fibro.

This is from F & Q page

IV clindamycin therapy is recommended in the treatment of all scleroderma

patients from mild to severe. When lab figures return to normal, these

patients may still require occasional IVs or a weekly dose of oral

clindamycin to remain stable.

.. Dr. Franco has substituted oral Zithromax (azithromycin) 250 mg. twice

daily for two days each week (Tues. Thurs.) in combination with oral Minocin

(Mon., Wed., Fri.).] When the initial course of IVs is completed, patients

begin oral therapy - minocycline (Minocin) or doxycycline (Vibramycin/Doryx)

100 mg. once or twice daily, or tetracycline 250 mg. to 500 mg. twice daily

Monday, Wednesday and Friday. This intermittent therapy (also referred to as

pulsing) is effective for most patients. More is not necessarily better;

however, in some cases, five or even seven-day a week doses may be necessary

for a limited time. The use of higher doses tends to make it more difficult

to keep the intestinal tract in balance. Patients with mild to moderate

disease are started with this same oral therapy, but often without the

initial week-long series of IV clindamycin at the beginning. Erythromycin

can be substituted for those patients sensitive to the tetracyclines

I'm sorry but I don't know anything else for scleroderma.

Hugs

cooky

Subject: RE: rheumatic AP minocycline dose

What about those with scleroderma, I thought they were supposed to take

everyday 2x / day?

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Cooky,

Thank you for your insightful comment about AP dose and schedule. I am just

impatient...and rather concerned as my anti-ccp levels increased from 90 to 134

in 5 months (above 60 is high). But I think you are wise...if I am seeing

results with 100mg MWF, then stick with that.

I also have been working hard to reduce any stress on my immune system. I have

stopped eating wheat/gluten and corn and I had the carpet removed from my

bedroom to reduce the presence of mold. Many healthcare practitioners are

realizing the role of mold in disease. I just did that before Christmas and I am

feeling better. So every little step in reducing stress on our immune system is

helpful.

Amy

>

> Hi Amy,

>

>

>

> Doctor Brown's protocol calls for MWF 100mgm 2 times a day. The reason for

> MWF is to prevent resistance and because mycos do not produce offspring

> (haha) everyday so you are wasting medicine. If you are improving on this

> dosage that is great and you should stay on it. The less medicine you take

> to get well the better. If progress stops you can increase to twice a day

> for a while to " kick start " it again. Good luck.

>

>

>

> cooky

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Cooky,

My ccp levels have increased while I have been on AP. The 90 ccp was in July

2010. I started mino in September (1+ months later) and then 5 months later (Dec

2010) ccp was 134. That's after being on AP for 4 months.

any thoughts? Amy

>

> Amy, So do you mean the ccp levels increased WHILE ON AP? Or was this

> before?

>

>

>

>

>

> From: rheumatic [mailto:rheumatic ] On Behalf

> Of Amy

> Sent: Wednesday, January 12, 2011 11:48 AM

> rheumatic

> Subject: rheumatic Re: AP minocycline dose

>

>

>

>

>

> Cooky,

>

> Thank you for your insightful comment about AP dose and schedule. I am just

> impatient...and rather concerned as my anti-ccp levels increased from 90 to

> 134 in 5 months (above 60 is high). But I think you are wise...if I am

> seeing results with 100mg MWF, then stick with that.

>

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