Guest guest Posted January 4, 2008 Report Share Posted January 4, 2008 , I can't comment much on thyroid since you don't have free T3 labs but likely the thyroid is stressing the already low adrenals even more. Your cortisol levels are low 3 out of 4 and your progesterone is very low. Don't go too high on your progesterone cream though...22 mg to 44 mg a day (you must measure) for 14 or 21 days depending on if you are pre or post menopausal. Likely your adrenals are pulling from progesterone to make up for what they aren't getting. I also recommend starting Isocort slowly, graphing temps and ramping up. Since your DHEA is still high enough, you are likely at stage 4 with DHEA still in range but since it is at the higher end you might be headed into stage 5. http://www.chronicfatigue.org/ASI%204.html http://www.chronicfatigue.org/ASI%205.html No, it is not odd to have DHEA high and progest and cortisol low. http://www.drlam.com/A3R_brief_in_doc_format/progesterone.cfm It is all about the stages of fatigue. Below is some info on progesterone and cortisol...Dr. Lam http://www.drlam.com/A3R_brief_in_doc_format/adrenal_fatigue.cfm has great info and you should read his entire adrenal section. This is also interesting on progesterone and cortisol if you get into scientific research journals like I do. http://www-personal.umich.edu/~oschult/publications/wmfs2007.pdf Looking over your symptoms and comparing to this matrix is a good idea: http://drrind.com/scorecardmatrix.asp Graph your temps three times daily and average per Dr. Rind http://drrind.com/tempgraph.asp#directions to track your progress and determine your dosage and ramping schedule of Isocort. All this info is in the file section of this group. Cheri PS: From Dr. Lam's site on progesterone: " Progesterone occupies an important position in the pathway of hormonal synthesis. In addition to being the precursor to estrogen, it is also the precursor of testosterone and the all-important adrenal cortical hormone cortisol. Cortisol is essential for stress response, sugar and electrolyte balance, blood pressure and general survival. In short, Progesterone serves to promote survival and development of the embryo and fetus. It acts as a precursor to many important steroid hormones and helps to regulate a broad range of biological and metabolic effects in the body. During chronic stress, Progesterone production is reduced as the body favors cortisol production to reduce stress. This is an important point which we will look into later. Progesterone and Adrenal Gland Optimization The adrenal gland has two compartments: the inner or medulla modulate the sympathetic nervous system through secretion and regulation of two hormones called epinephrine and nor epinephrine that are responsible for the fight or flight response. The adrenal cortex secretes three classes of hormones - glucocorticoids, mineralcorticoids and androgens. The most important glucocorticoids are cortisol and hydrocortisone. Reduced output of these hormones often result from chronic stress of the adrenal glands or malnutrition. Symptoms include fatigue, low blood sugar, weight loss and menstrual dysfunction. Mineralcorticoids such as aldosterone modulate the delicate balance of minerals in the cell, especially sodium and potassium. Stress increases the release of aldosterone, causing sodium retention (leading to water retention and high blood pressure) and loss of potassium and magnesium. Magnesium is involved in over 300 enzymatic reactions in the body. Its deficiency is widespread and has been linked to a variety of pathological conditions, including cardiac arrhythmias, uterine fibroids and osteoporosis. The adrenal cortex also produces all of the sex hormones, although in small amounts. One exception is DHEA, a weak androgenic hormone that is made in large amounts in both sexes. DHEA, together with testosterone and estrogen, are made from pregnenolone, which in turn comes from cholesterol. Progesterone is therefore at the top of an important hormonal metabolic pathway. Deficiency in Progesterone leads to reduction of both glucocorticosteroids and mineralcorticoids such as cortisol. Deficiency symptoms of cortisol include fatigue, immune dysfunction, hypoglycemia, allergies and arthritis. Deficiency in mineralcorticoids include high blood pressure and mineral imbalances. Progesterone supplement often effectively resolve these problems. ....With chronic stress, eventually the adrenals are exhausted and production of these important hormones are drastically reduced. " -----Original Message----- Hi, I'm new here. I've been reading thru the files saved here and have spent the last week reading articles online on the subject. I'm learning alot, and I'm finding some conflicting info. I'd like to know where to start in order to heal. Do you mind reviewing my situation and giving me some advice? Diagnosed with postpartum thyroiditis in 2002. Been on Armour since 2005 (subclinical hypothyroidism) After stressful year (good riddance 2007!) and feeling crummy, did bloodwork listed below. Symptoms that started this fall include: Heart palpatations, anxiety (trying to sell house in the current market!), difficulty falling asleep, Minor incontinence, memory issues, slight depression, evening fatigue until 9 pm, no libido, feeling dehydrated, occasional dizziness, dandruff, irritable, emotional. Blood tests: TSH 13 Free T4 .7 (.8-1.8) Thyroid Peroxidase Antibodies >1000 Other antibodies, iron levels, and ferritin are normal. T3 not checked. My conclusion is that I have Hashimotos. I increased Armour dosage from 105 to 120 mg after test results. Also started gluten free diet. Started Pro-gest by emerita yesterday (day 12 of cycle). Applying cream morning and night. Adding sea salt to water, trying to get to sleep earlier (by 10:30), and after reading some of the files, considering starting yeast detox. Also considering buying licorice extract. Does it seem odd that my DHEAs are so high with progesterone and thyroid being low? Any ideas what I should treat first? I'm really looking forward to getting back to normal. Please help!! Thanks!! . Quote Link to comment Share on other sites More sharing options...
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