Guest guest Posted March 14, 2010 Report Share Posted March 14, 2010 Hi All, Both my daughter's have megablastic anemia, one has recently tested positive for Hashi's/need to test the other one. But I'm wondering if their megablastic anemia (not iron-deficiency anemia) is related to hypothyroidism? I'm thinking they could be related genetically. Or perhaps once the Hashi's is properly medicated, the megablastic anemia will go away. Right now they take active folate and B12 to counteract the M.A. I'm just wondering if M.A. is common among Hashi's patients? We have an appt. with Stanford Pediatric Endocrinoloyg and their Hematology departments soon. I can tell you what I learn if anyone else is interested in how these 2 conditions might related. Debra in CA Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 15, 2010 Report Share Posted March 15, 2010 Not sure of a direct link, but HypoT patients do tend toward b12 deficiency, which, if extreme, leads to megaloblastic anemia. I had MA, which was resolved by correct b12 supplementation. I take five THOUSAND mcg of sublingual b12 daily. I HAVE to take it sublingually - my MA was caused by my stomach's inability to absorb swallowed b12. Vegetarians are particularly prone to MA, as most of the b12 in our diets comes from meat sources. The 5000 mcg sublingual supplement will fix up our Veg friends, too. Good MA info http://en.wikipedia.org/wiki/Megaloblastic_anemia Why sublingual b12 works when swallowed b12 fails http://en.wikipedia.org/wiki/Sublingual_administration b12 I currently take http://www.amazon.com/Mega-B-12-Dots-5000mcg-dots/dp/B00014DUTS/ref=sr_1_1?ie=UT\ F8 & s=hpc & qid=1268700795 & sr=8-1 this is the cyanocobalamin form; I have read that the methylcobalamin form is better; I have not seen much effective difference between the two, but take methylcobalamin occasionally. http://www.wonderlabs.com/itemleft.php?itemnum=9841 Hope this helps. > > Hi All, > > Both my daughter's have megablastic anemia, one has recently tested positive for Hashi's/need to test the other one. But I'm wondering if their megablastic anemia (not iron-deficiency anemia) is related to hypothyroidism? I'm thinking they could be related genetically. Or perhaps once the Hashi's is properly medicated, the megablastic anemia will go away. Right now they take active folate and B12 to counteract the M.A. > > I'm just wondering if M.A. is common among Hashi's patients? We have an appt. with Stanford Pediatric Endocrinoloyg and their Hematology departments soon. I can tell you what I learn if anyone else is interested in how these 2 conditions might related. > > Debra in CA > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 15, 2010 Report Share Posted March 15, 2010 Not sure of a direct link, but HypoT patients do tend toward b12 deficiency, which, if extreme, leads to megaloblastic anemia. I had MA, which was resolved by correct b12 supplementation. I take five THOUSAND mcg of sublingual b12 daily. I HAVE to take it sublingually - my MA was caused by my stomach's inability to absorb swallowed b12. Vegetarians are particularly prone to MA, as most of the b12 in our diets comes from meat sources. The 5000 mcg sublingual supplement will fix up our Veg friends, too. Good MA info http://en.wikipedia.org/wiki/Megaloblastic_anemia Why sublingual b12 works when swallowed b12 fails http://en.wikipedia.org/wiki/Sublingual_administration b12 I currently take http://www.amazon.com/Mega-B-12-Dots-5000mcg-dots/dp/B00014DUTS/ref=sr_1_1?ie=UT\ F8 & s=hpc & qid=1268700795 & sr=8-1 this is the cyanocobalamin form; I have read that the methylcobalamin form is better; I have not seen much effective difference between the two, but take methylcobalamin occasionally. http://www.wonderlabs.com/itemleft.php?itemnum=9841 Hope this helps. > > Hi All, > > Both my daughter's have megablastic anemia, one has recently tested positive for Hashi's/need to test the other one. But I'm wondering if their megablastic anemia (not iron-deficiency anemia) is related to hypothyroidism? I'm thinking they could be related genetically. Or perhaps once the Hashi's is properly medicated, the megablastic anemia will go away. Right now they take active folate and B12 to counteract the M.A. > > I'm just wondering if M.A. is common among Hashi's patients? We have an appt. with Stanford Pediatric Endocrinoloyg and their Hematology departments soon. I can tell you what I learn if anyone else is interested in how these 2 conditions might related. > > Debra in CA > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 15, 2010 Report Share Posted March 15, 2010 I'm definitely interested - please keep us/me posted. My CBC looked fine, with the exception of an under-range white blood cell count. And my B-12 result was low - 238 (211 - 911). I have Hashi's. B-12 deficiency is definitely linked to Hashi's. > > Hi All, > > Both my daughter's have megablastic anemia, one has recently tested positive for Hashi's/need to test the other one. But I'm wondering if their megablastic anemia (not iron-deficiency anemia) is related to hypothyroidism? I'm thinking they could be related genetically. Or perhaps once the Hashi's is properly medicated, the megablastic anemia will go away. Right now they take active folate and B12 to counteract the M.A. > > I'm just wondering if M.A. is common among Hashi's patients? We have an appt. with Stanford Pediatric Endocrinoloyg and their Hematology departments soon. I can tell you what I learn if anyone else is interested in how these 2 conditions might related. > > Debra in CA > Quote Link to comment Share on other sites More sharing options...
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