Re: stiffness at nite with Doxycycline

[Guest guest]

It is certainly odd that the stiffness goes away during the day. Seems

inactivity as you sleet causes an issue. I agree with all the others that

perhaps instead of Doxycyline you try using EITHER the BRAND Vibramycin, or a

generic MINOCYCLINE. The latter is shown to have a greater efficacy in

penetrating into the joints to combat whatever is causing the inflammation. I

use TEVA brand minocycline right how, but have used two other brands, and ALL

WORKED WONDERFULLY. By contrast the generic doxycyline (watson) worked for a

while, wonderfully, then they changed their supplier of one or more inert

ingredients. It was over a period of several months, but my situation degraded

substantially, until I could no longer see any benefit whatsoever from the

drug.tThe inert ingredients are key to the delivery system, especially for RA.

If the molecules are too large, the stuff cannot penetrate the joint areas.

Supplements are nice, but there is something underlying that is not working as

well as it should. Generic minocycline is everywhere and not expensive at all.

(see my postings...I had a roller coaster ride due to doxycycline issues...now I

use VIBRAMYCIN one month, then MINOCYCLINE the next month...same dosage. You can

jump start improvement by using two 100mg doses per day for 7 days a week for a

few weeks...as you improve, gradually reduce the dosage to whatever keeps it

going.

Good luck - Tish

>

> Hello all,

>

> I would like to address a question to those who feel they are in remission

> or close to remission or just to anyone who is going through this.

>

> THough my day pain has vastly improved, my nights have become sheer terror.

> Before the doxi I never had any stiffness or pain when sleeping ( or

> stiffness during the day either) Now when I wake in the middle of the

> night, my elbows, shoulders, and knees ( especilly the knees) feel like

> they are cemented together. When I try to straighten my knees or bend them,

> they are " stuck " . I almost can not move them. When I do get them to move,

> the pain is so great I feel as if I am going to pass out.

>

> Is this unusal or just part of the treatment? By day, I am doing pretty

> much anything I want to, but by night I am getting worse and worse.

>

> I am scared to death over this . I feel the doxi must be accelerating this

> disease since I have never had any night stiffness or day stiffness before

> the AP.

>

> Any thoughts are appreciated very much.

> Thanks!

>

>

>