Guest guest Posted July 12, 2008 Report Share Posted July 12, 2008 Hi I began the plaquenil in August 2006 and in October added minocycline 100mg MWF. By January I was pretty well pain free. I continued with the plaquenil for another 15 months because it controlled the pain and inflammation, though I still had quite a bit which flared and died down all year, seemingly with no pattern. In January this year I decided to stop the Plaq and see what happened and in April my pain levels went up quite a lot. About 3 weeks ago I decided to give the plaq another try (along with the minocycline) and I seem quite a bit better - I can walk reasonably well again anyway. So I don't think it's harmful to take plaquenil with minocycline. Being a mild DMARD it may even reduce the inflammation so that the mino can do its work better and faster. It's important to keep the inflammation under control when taking mino or it's less effective. I've been using NSAIDS but they play havoc with my digestive system so I can't do that any more. I haven't had any problems with my eyes so far and was told that though eye problems are possible, they are very few and far between. It's a journey of exploration and experiment to find the most effective drug procedures for each of us. I'm sure you will discover your best way of controlling this disease with a little tweaking here and there. Ros Quote Link to comment Share on other sites More sharing options...
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