Guest guest Posted June 5, 2009 Report Share Posted June 5, 2009 Hi, need you guys again to help in evaluating which drugs is actually impacting my condition. I swicthed from generic to brand name mino on May 15th and seem to experience a new wave of herxing. It was so bad I thought I might need crutches soon to walk, but at the same time also noticed 2 good days in between. Rather relunctantly, I started MTX (DMARD) last friday morning (May 29th). Here is the tricky part, I felt pretty good on the same day I took MTX and was able to skip Naproxen (NSAID) on that day which I've never done in 3 months. Will that be my immune system was responding to a new drug & gave me a break in banging my joints OR perhaps the AP has started to work. I dont believe MTX has kicked in just a couple of hours after taking it. Here is the best part, since last friday until now, I've experienced 4 painful days (WITH-NSAID) and 3 good days (without-NSAID). This is a miracle for me as I have not experienced so much in one week in the past 3 months. Even now my knees got better in walking. EVALUATING PART: If AP has started to work - I consider it a good news. Today I did not even take my second dose of MTX. If this is the effect of MTX - nothing to boast about. Everything will continue as has planned. Does anyone has any experience with MTX about the timing it normally works. I learned from the web source that it takes 3-6 weeks to see sign of improvement and 8-12 weeks for a full benefit. Will it work within 7 days?? (Hopefully not MTX cos I want to give full credit to AP) C Quote Link to comment Share on other sites More sharing options...
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