Minocycline as an immune modifier

[Guest guest]

>>>I heard from Dr. whitmann that minocin is immune modifier.<<<

Hi All,

Thought I'd read something about this in The New Arthritis Breakthrough, by

Henry Scammell and checked it out. If you have the book, check out pg 280 in

the section entitled: " Minocycline and the NIH Clinical Trials. " Here's the

relevant bit where there is a discussion on what provided the rationale for the

further study of minocycline in the MIRA Trials:

" Minocycline may help patients with rheumatoid arthritis because it

eliminates and infectious agent. Alternatively, arthritis research in animal

systems

has shown the minocycline affects calcium metabolism or pathways in T Cells;and

calcium pathways are a critical component of the ways in which T Cells

activate themselves or function. T Cells exposed to minocycline take up too much

calcium internally, and then become sick or malfunctional. They seem to quiet

down, and the animals go into complete remission or are at least visibly

improved

by the therapy. This new information favors the possibility that some

antibiotic drugs may be benefiial in rheumatoid arthritis because they eliminate

these

T Cell autoimmune responses, and not just because they home in on an

infectious agent. "

So, according to these animal studies that were part of the fuel behind the

MIRA studies, in addition to being used in the war waged against mycoplasma,

apparently minocycline may also have some effect as an immune modulator, while

also tuning down inflammation. I guess unless actual human studies are

performed, all the wonderful properties of our miracle minocycline won't be

known for

sure?

Peace, Maz