High serum iron/high saturation but LOW ferritin

[Guest guest]

Several folks have written in on this puzzling test result. It often occurs

because of B12 deficiency (a.k.a. pernicious anemia).

" The serum iron level and transferrin saturation often are artifactually high in

patients with pernicious anemia "

from

http://sickle.bwh.harvard.edu/fe-def.html

[Guest guest]

That is a very interesting idea. My iron levels came back as

Iron TIBC 296 <250-450>

UIBC 151 <150-275>

Iron serum 145 <35-155>

Iron saturation 49% <15-55>

Ferritin 20 <10-291>

My B12 last check was actually rather high but I wasn't taking the right B12. I have been taking the 5000mcg methylcobalamin for a few weeks now so hopefully if I have a B12 issue that will help. I have Celiac disease along with poor absorption.

Do you think it is safe for me to supplement iron with numbers like this? I know my ferritin needs to come up. Also, does pernicious anemia cause the ferritin to stay low? At one point about two years after my celiac diagnosis my Ferritin was TWO.

Thanks for any info!

Kitty

To: RT3_T3 Sent: Tue, March 30, 2010 10:24:14 AMSubject: High serum iron/high saturation but LOW ferritin

Several folks have written in on this puzzling test result. It often occurs because of B12 deficiency (a.k.a. pernicious anemia)."The serum iron level and transferrin saturation often are artifactually high in patients with pernicious anemia"fromhttp://sickle. bwh.harvard. edu/fe-def. html

[Guest guest]

That is a very interesting idea. My iron levels came back as

Iron TIBC 296 <250-450>

UIBC 151 <150-275>

Iron serum 145 <35-155>

Iron saturation 49% <15-55>

Ferritin 20 <10-291>

My B12 last check was actually rather high but I wasn't taking the right B12. I have been taking the 5000mcg methylcobalamin for a few weeks now so hopefully if I have a B12 issue that will help. I have Celiac disease along with poor absorption.

Do you think it is safe for me to supplement iron with numbers like this? I know my ferritin needs to come up. Also, does pernicious anemia cause the ferritin to stay low? At one point about two years after my celiac diagnosis my Ferritin was TWO.

Thanks for any info!

Kitty

To: RT3_T3 Sent: Tue, March 30, 2010 10:24:14 AMSubject: High serum iron/high saturation but LOW ferritin

Several folks have written in on this puzzling test result. It often occurs because of B12 deficiency (a.k.a. pernicious anemia)."The serum iron level and transferrin saturation often are artifactually high in patients with pernicious anemia"fromhttp://sickle. bwh.harvard. edu/fe-def. html

[Guest guest]

Thanks for posting this tidbit. Very interesting and helpful.

L

>

[Guest guest]

Thanks for posting this tidbit. Very interesting and helpful.

L

>

[Guest guest]

Thanks for posting this tidbit. Very interesting and helpful.

L

>

[Guest guest]

High iron serum & saturation accompanied by low ferritin may indicate something

is impairing the formation of new blood cells (hematopoiesis). Since the iron

isn't being used for forming red blood cells, iron may build up in the blood.

B12 deficiency is a common cause of impaired hematopoiesis.

Impaired hematopoiesis is probably not correctly described as a disease, but

rather as a symptom of something else. In addition to b12 deficiency, it can

have many other causes; inadequate nutrition and autoimmune issues are two.

I'm sorry I don't know enough to answer your other questions. I have heard that

methylcobalamin is the best form of b12 to take.

http://sickle.bwh.harvard.edu/fe-def.html

>

> That is a very interesting idea. My iron levels came back as

> Iron TIBC 296 <250-450>

> UIBC 151 <150-275>

> Iron serum 145 <35-155>

> Iron saturation 49% <15-55>

> Ferritin 20 <10-291>

>

> My B12 last check was actually rather high but I wasn't taking the right B12.

I have been taking the 5000mcg methylcobalamin for a few weeks now so hopefully

if I have a B12 issue that will help. I have Celiac disease along with poor

absorption.

>

> Do you think it is safe for me to supplement iron with numbers like this? I

know my ferritin needs to come up. Also, does pernicious anemia cause the

ferritin to stay low? At one point about two years after my celiac diagnosis my

Ferritin was TWO.

>

> Thanks for any info!

>

> Kitty

>

>

>

>

>

> ________________________________

>

> To: RT3_T3

> Sent: Tue, March 30, 2010 10:24:14 AM

> Subject: High serum iron/high saturation but LOW ferritin

>

>

> Several folks have written in on this puzzling test result. It often occurs

because of B12 deficiency (a.k.a. pernicious anemia).

>

> " The serum iron level and transferrin saturation often are artifactually high

in patients with pernicious anemia "

>

> from

>

> http://sickle. bwh.harvard. edu/fe-def. html

>

[Guest guest]

High iron serum & saturation accompanied by low ferritin may indicate something

is impairing the formation of new blood cells (hematopoiesis). Since the iron

isn't being used for forming red blood cells, iron may build up in the blood.

B12 deficiency is a common cause of impaired hematopoiesis.

Impaired hematopoiesis is probably not correctly described as a disease, but

rather as a symptom of something else. In addition to b12 deficiency, it can

have many other causes; inadequate nutrition and autoimmune issues are two.

I'm sorry I don't know enough to answer your other questions. I have heard that

methylcobalamin is the best form of b12 to take.

http://sickle.bwh.harvard.edu/fe-def.html

>

> That is a very interesting idea. My iron levels came back as

> Iron TIBC 296 <250-450>

> UIBC 151 <150-275>

> Iron serum 145 <35-155>

> Iron saturation 49% <15-55>

> Ferritin 20 <10-291>

>

> My B12 last check was actually rather high but I wasn't taking the right B12.

I have been taking the 5000mcg methylcobalamin for a few weeks now so hopefully

if I have a B12 issue that will help. I have Celiac disease along with poor

absorption.

>

> Do you think it is safe for me to supplement iron with numbers like this? I

know my ferritin needs to come up. Also, does pernicious anemia cause the

ferritin to stay low? At one point about two years after my celiac diagnosis my

Ferritin was TWO.

>

> Thanks for any info!

>

> Kitty

>

>

>

>

>

> ________________________________

>

> To: RT3_T3

> Sent: Tue, March 30, 2010 10:24:14 AM

> Subject: High serum iron/high saturation but LOW ferritin

>

>

> Several folks have written in on this puzzling test result. It often occurs

because of B12 deficiency (a.k.a. pernicious anemia).

>

> " The serum iron level and transferrin saturation often are artifactually high

in patients with pernicious anemia "

>

> from

>

> http://sickle. bwh.harvard. edu/fe-def. html

>

[Guest guest]

High iron serum & saturation accompanied by low ferritin may indicate something

is impairing the formation of new blood cells (hematopoiesis). Since the iron

isn't being used for forming red blood cells, iron may build up in the blood.

B12 deficiency is a common cause of impaired hematopoiesis.

Impaired hematopoiesis is probably not correctly described as a disease, but

rather as a symptom of something else. In addition to b12 deficiency, it can

have many other causes; inadequate nutrition and autoimmune issues are two.

I'm sorry I don't know enough to answer your other questions. I have heard that

methylcobalamin is the best form of b12 to take.

http://sickle.bwh.harvard.edu/fe-def.html

>

> That is a very interesting idea. My iron levels came back as

> Iron TIBC 296 <250-450>

> UIBC 151 <150-275>

> Iron serum 145 <35-155>

> Iron saturation 49% <15-55>

> Ferritin 20 <10-291>

>

> My B12 last check was actually rather high but I wasn't taking the right B12.

I have been taking the 5000mcg methylcobalamin for a few weeks now so hopefully

if I have a B12 issue that will help. I have Celiac disease along with poor

absorption.

>

> Do you think it is safe for me to supplement iron with numbers like this? I

know my ferritin needs to come up. Also, does pernicious anemia cause the

ferritin to stay low? At one point about two years after my celiac diagnosis my

Ferritin was TWO.

>

> Thanks for any info!

>

> Kitty

>

>

>

>

>

> ________________________________

>

> To: RT3_T3

> Sent: Tue, March 30, 2010 10:24:14 AM

> Subject: High serum iron/high saturation but LOW ferritin

>

>

> Several folks have written in on this puzzling test result. It often occurs

because of B12 deficiency (a.k.a. pernicious anemia).

>

> " The serum iron level and transferrin saturation often are artifactually high

in patients with pernicious anemia "

>

> from

>

> http://sickle. bwh.harvard. edu/fe-def. html

>

[Guest guest]

It might be the Hashi's. As soon as I saw " autoimmune " as one of the causes of

impaired hematopoiesis, I wondered if you had Hashi's. It seems likely that a

Hashi's flare-up would adversely effect iron utilization. Conversely, during

the times when the Hashi's is quiet, iron is probably utilized a lot better.

This makes a lot of sense, since many folks here have asked about this iron test

result, and many folks here have Hashi's, too.

Celiac is notorious for causing iron deficiency. Celiac (as you know all too

well) causes malabsorption and malnutrition

http://www.medicinenet.com/celiac_disease/page7.htm

Malnutrition is another cause of impaired hematopoiesis.

The good news is that there should be times, when both the Hashi's and the

celiac are quieter, that it should be possible to successfully supplement iron

and raise ferritin.

> >

> > That is a very interesting idea. My iron levels came back as

> > Iron TIBC 296 <250-450>

> > UIBC 151 <150-275>

> > Iron serum 145 <35-155>

> > Iron saturation 49% <15-55>

> > Ferritin 20 <10-291>

> >

> > My B12 last check was actually rather high but I wasn't taking the right

B12. I have been taking the 5000mcg methylcobalamin for a few weeks now so

hopefully if I have a B12 issue that will help. I have Celiac disease along with

poor absorption.

> >

> > Do you think it is safe for me to supplement iron with numbers like this? I

know my ferritin needs to come up. Also, does pernicious anemia cause the

ferritin to stay low? At one point about two years after my celiac diagnosis my

Ferritin was TWO.

> >

> > Thanks for any info!

> >

> > Kitty

> >

> >

> >

> >

> >

> > ____________ _________ _________ __

> > From: Margery__W <m.escoffery@ ...>

> > To: RT3_T3yahoogroups (DOT) com

> > Sent: Tue, March 30, 2010 10:24:14 AM

> > Subject: High serum iron/high saturation but LOW ferritin

> >

> >

> > Several folks have written in on this puzzling test result. It often occurs

because of B12 deficiency (a.k.a. pernicious anemia).

> >

> > " The serum iron level and transferrin saturation often are artifactually

high in patients with pernicious anemia "

> >

> > from

> >

> > http://sickle. bwh.harvard. edu/fe-def. html

> >

>

[Guest guest]

It might be the Hashi's. As soon as I saw " autoimmune " as one of the causes of

impaired hematopoiesis, I wondered if you had Hashi's. It seems likely that a

Hashi's flare-up would adversely effect iron utilization. Conversely, during

the times when the Hashi's is quiet, iron is probably utilized a lot better.

This makes a lot of sense, since many folks here have asked about this iron test

result, and many folks here have Hashi's, too.

Celiac is notorious for causing iron deficiency. Celiac (as you know all too

well) causes malabsorption and malnutrition

http://www.medicinenet.com/celiac_disease/page7.htm

Malnutrition is another cause of impaired hematopoiesis.

The good news is that there should be times, when both the Hashi's and the

celiac are quieter, that it should be possible to successfully supplement iron

and raise ferritin.

> >

> > That is a very interesting idea. My iron levels came back as

> > Iron TIBC 296 <250-450>

> > UIBC 151 <150-275>

> > Iron serum 145 <35-155>

> > Iron saturation 49% <15-55>

> > Ferritin 20 <10-291>

> >

> > My B12 last check was actually rather high but I wasn't taking the right

B12. I have been taking the 5000mcg methylcobalamin for a few weeks now so

hopefully if I have a B12 issue that will help. I have Celiac disease along with

poor absorption.

> >

> > Do you think it is safe for me to supplement iron with numbers like this? I

know my ferritin needs to come up. Also, does pernicious anemia cause the

ferritin to stay low? At one point about two years after my celiac diagnosis my

Ferritin was TWO.

> >

> > Thanks for any info!

> >

> > Kitty

> >

> >

> >

> >

> >

> > ____________ _________ _________ __

> > From: Margery__W <m.escoffery@ ...>

> > To: RT3_T3yahoogroups (DOT) com

> > Sent: Tue, March 30, 2010 10:24:14 AM

> > Subject: High serum iron/high saturation but LOW ferritin

> >

> >

> > Several folks have written in on this puzzling test result. It often occurs

because of B12 deficiency (a.k.a. pernicious anemia).

> >

> > " The serum iron level and transferrin saturation often are artifactually

high in patients with pernicious anemia "

> >

> > from

> >

> > http://sickle. bwh.harvard. edu/fe-def. html

> >

>