Guest guest Posted April 7, 2010 Report Share Posted April 7, 2010 >Since you missed several post I thought I would ask these again. Thanks, I fell behind with life getting in the way! > >1) Have you heard of T3 only causing sex hormone to bind and thus causing issues of low testosterone? This is not specific to T3. Hypo thyroid = low SHBG = relatively high levels of Free sex hormones (ie unbound) Normal thyroid = Normal SHBG. If you are transitioning from a hypothyroid state it may take time for the Free sex hormones to catch back up to a normal level. It seems probable that a rise in SGBH binds the free T that is there at the time but as more is produced and the SHGB is at a new constant level then the free levels will increase back to normal once the higher levels of SHBG have been filled up with T. Hyper Thyroid (ie excessive levels of T3 as used by body builders to lose weight) = high SHBG = low free sex hormones = unhappy body builders who are also supplementing Testosterone to try and build muscle. The issue is no more than a transient one at normal T3 doses, it gets publicity because of the use of T3 in the body building community. T3 only does not have a different effect on SHBG to T4/T3 combinations, it's your thyroid status that influences it The body builders deliberately get hyper in the hopes of losing weight and get frustrated when they lose muscle mass with it.. > >2) If someone had a high RT3 ratio and now it is low normal, but they have never went T3 only to clear receptors completely, won't the blocked receptors eventually clear or does this only happen on T3 only? I ask this because it seems strange that this is an all or nothing issue. It would seem that just getting RT3 into the normal range would eventually clear receptors enough to feel normal. We don't know. We do know that if you take RT3 to virtually zero it still takes weeks before receptors clear. Nobody knows how low the RT3 has to be for that to happen. This is fairly frontier work and the studies have not been done, a way that works is known but the other possible options have not been evaluated. > >3) I looked back at one of my post to you last October and I was taking 2 grains dessicated and 45mcg slow release T3. I felt better then than I do now on 2 grains dessicated and 120mcg slow release T3. My dr. thinks I could have too much T3, although I don't feel like it. My muscle pains and recovery are worse than they have been for a couple of years. I was up to 2.5 grains and he wants me down to 1.5 and if I feel bad to up the T3 even more. The only good effect I feel now that I have lowered dosage is I don't feel so amped up which was definately causing my muscles to feel tense, but my heart rate and temps are not high. Any suggestions? What are temperature and pulse doing? > Have you recent labs?? thyroid, ferritin, cortisol, Vitamins D and B12, and electrolytes all play a big part in this puzzle. Have you tried dropping the natural completely? You are still taking 78 of T4 and that's more than enough to keep feeding the RT3 Nick -- for more information on RT3 and Thyroid Resistance go to www.thyroid-rt3.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2010 Report Share Posted April 7, 2010 >Since you missed several post I thought I would ask these again. Thanks, I fell behind with life getting in the way! > >1) Have you heard of T3 only causing sex hormone to bind and thus causing issues of low testosterone? This is not specific to T3. Hypo thyroid = low SHBG = relatively high levels of Free sex hormones (ie unbound) Normal thyroid = Normal SHBG. If you are transitioning from a hypothyroid state it may take time for the Free sex hormones to catch back up to a normal level. It seems probable that a rise in SGBH binds the free T that is there at the time but as more is produced and the SHGB is at a new constant level then the free levels will increase back to normal once the higher levels of SHBG have been filled up with T. Hyper Thyroid (ie excessive levels of T3 as used by body builders to lose weight) = high SHBG = low free sex hormones = unhappy body builders who are also supplementing Testosterone to try and build muscle. The issue is no more than a transient one at normal T3 doses, it gets publicity because of the use of T3 in the body building community. T3 only does not have a different effect on SHBG to T4/T3 combinations, it's your thyroid status that influences it The body builders deliberately get hyper in the hopes of losing weight and get frustrated when they lose muscle mass with it.. > >2) If someone had a high RT3 ratio and now it is low normal, but they have never went T3 only to clear receptors completely, won't the blocked receptors eventually clear or does this only happen on T3 only? I ask this because it seems strange that this is an all or nothing issue. It would seem that just getting RT3 into the normal range would eventually clear receptors enough to feel normal. We don't know. We do know that if you take RT3 to virtually zero it still takes weeks before receptors clear. Nobody knows how low the RT3 has to be for that to happen. This is fairly frontier work and the studies have not been done, a way that works is known but the other possible options have not been evaluated. > >3) I looked back at one of my post to you last October and I was taking 2 grains dessicated and 45mcg slow release T3. I felt better then than I do now on 2 grains dessicated and 120mcg slow release T3. My dr. thinks I could have too much T3, although I don't feel like it. My muscle pains and recovery are worse than they have been for a couple of years. I was up to 2.5 grains and he wants me down to 1.5 and if I feel bad to up the T3 even more. The only good effect I feel now that I have lowered dosage is I don't feel so amped up which was definately causing my muscles to feel tense, but my heart rate and temps are not high. Any suggestions? What are temperature and pulse doing? > Have you recent labs?? thyroid, ferritin, cortisol, Vitamins D and B12, and electrolytes all play a big part in this puzzle. Have you tried dropping the natural completely? You are still taking 78 of T4 and that's more than enough to keep feeding the RT3 Nick -- for more information on RT3 and Thyroid Resistance go to www.thyroid-rt3.com Quote Link to comment Share on other sites More sharing options...
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