T3-Reduces testosterone

[Guest guest]

Enclosed is one of the articles I stumbled on....since T3 is needed by the body

this doesn't make sense...unless the T4 to T3 conversion process in some way

ensures that T3 doesn't negatively impact SHBG levels.

" Now you see another reason why people are told to NOT take t3 with H or

anything else. It increases SHBG! That being said, this little diddy also

explains why somebody like me with low T levels and hypothyroid puts on muscle

and/or retains it so well. BECAUSE MY SHBG IS LIKELY ALMOST ZERO!

Opposite effects of thyroid hormones on binding proteins for steroid hormones

(sex hormone binding globulin and

corticosteroid binding globulin) in humans [published erratum appears in Eur J

Endocrinol 1995 Sep;133(3):381

Author Dumoulin SC; Perret BP; Bennet AP; Caron PJ

Address

Department of Endocrinology' CHU Rangueil' Toulouse' France.

Source

Eur J Endocrinol, 132(5):594 8 1995 May

Abstract

Sex hormone binding globulin (SHBG) and corticosteroid binding globulin (CBG)

levels were evaluated in euthyroid

(N = 111)' hyper (N = 58) and hypothyroid (N = 38) men' in pre and

postmenopausal women (study 1) and in

hyper (N = 24) and hypothyroid (N = 15) patients before and after treatment with

carbimazole or levothyroxine

therapy (study 2). The SHBG levels are increased in hyper and decreased in

hypothyroid patients' whereas CBG

levels are increased in hypo and decreased in hyperthyroid patients. The SHBG

levels are higher in women than in

men with similar thyroid status. Plasma SHBG levels are correlated positively

whereas CBG levels are correlated

negatively with free thyroid hormone concentrations in men as well as women. In

hypothyroid patients' SHBG

concentrations increased (p < 0.01) and CBG concentrations decreased (p < 0.01)

during levothyroxine treatment. In

hyperthyroid patients' SHBG concentrations decreased (p < 0.01) and CBG

concentrations increased (p < 0.01)

during antithyroid treatment. The SHBG and CBG concentrations in treated hypo

and hyperthyroid patients were not

significantly different from those of euthyroid controls. Our data indicate that

SHBG and CBG levels depend on thyroid

status. Corticosteroid binding globulin is an index of thyroid hormone action at

the liver level whose changes are

opposite to those of SHBG in hyper and hypothyroidism.

And such, my little hobbits is EXACTLY why you lose muscle mass on T3. It IS NOT

because of the t3 directly, but because it increases your shbg thereby locking

up your testosterone and if you are dieting after a cycle with no AS at all, you

can easily see how easy it would be to fuck yourself.