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St. Jude Medical to Highlight Broad Portfolio of Innovative Medical

Technologies at Boston Atrial Fibrillation Symposium

Boston Atrial Fibrillation Symposium

ST. PAUL, Minn.--(BUSINESS WIRE)--Jan. 12, 2006--St. Jude Medical, Inc.

(NYSE:STJ) will demonstrate its broad range of cardiac care

technologies--including advanced cardiac visualization and navigation

technology, a surgical cardiac ablation system, and a full line of

catheter-based diagnostic and therapeutic products--at the Boston Atrial

Fibrillation Symposium, January 13 - 14, 2006.

St. Jude Medical supports this important clinical meeting annually in order

to advance the study and management of atrial fibrillation (AF) throughout

the world. Atrial fibrillation is a debilitating condition characterized by

the rapid, unsynchronized quivering of the heart's atria (upper chambers).

AF is the world's most common cardiac arrhythmia, affecting more than 6

million people worldwide.

In addition to presenting its extensive product lines, St. Jude Medical is

sponsoring several events at this year's Boston AF Symposium, including:

-- Shaping the Future of Atrial Fibrillation Management

Warren M. Jackman, M.D. and Pierre Jais, M.D., along with St.

Jude Medical, are hosting an educational symposium that will

feature numerous experts in the field of atrial fibrillation.

The speakers include some of the most well-respected

physicians in this field, such as: Shih-Ann Chen, M.D.;

Natale, M.D.; Matthias Antz, M.D.; Koonlawee Nademanee, M.D.;

Sherlag, M.D.; and Hiroshi Nakagawa, M.D. Topics will

cover current treatment options as well as the potential of

future modalities.

-- Extreme High-Altitude Medicine

NASA astronaut and physician E. Parazynski, M.D. will

discuss the intricacies of medicine in space. The event, which

will be held at the F. Kennedy Library in Boston, will

allow attendees to gain a new perspective on the state of

medicine today, and what it may entail in the future.

" St. Jude Medical is proud to play a role in the success of the Boston

Atrial Fibrillation Symposium, " said Jane J. Song, President of St. Jude

Medical's Atrial Fibrillation Division. " It is a unique opportunity for

focused discussion and discovery surrounding this prevalent disease,

bringing together international leaders in AF treatment and allowing them to

collaborate on how to bring more effective products and techniques to

patients around the world. "

St. Jude Medical will demonstrate a complete line of products for access,

diagnosis, visualization, and therapy at Booth #529. Featured products will

include:

-- The EnSite® System Version 5.1, which provides outstanding speed and

flexibility for the electrophysiology (EP) lab with MultiPoint

Technology--a function that allows physicians to gather voltage and

activation data with greater speed and efficiency.

-- EnSite Verismo Segmentation Software, which uses CT and MRI slice

data to quickly create accurate 3-dimensional models of patient cardiac

anatomy.

-- The Agilis Steerable Introducer, which offers outstanding agility and

stability, and with appropriate therapeutic catheters, helps create precise

cardiac ablation lesions. It also offers a steering mechanism to allow

micro-movements with an ablation catheter, along with atraumatic and

radiopaque tip markers designed to facilitate safe movement within the

atria.

-- The IBI-1500T6 Cardiac Ablation Generator and Therapy

Electrophysiology Catheters, recently launched in the U.S. market, which

further expand St. Jude Medical's therapeutic EP portfolio. The 100-watt

IBI-1500T6 generator offers a user-friendly programming platform and

monitors all critical performance variables. The Therapy Dual-8

Ablation Catheters are designed with an 8mm tip electrode containing

dual-temperature sensors for enhanced temperature control when creating

long, linear lesions. The 4mm tip Therapy Ablation Catheters offer a

reliable and accurate single-sensor temperature monitoring system for the

treatment of supraventricular tachycardias. Both catheter models provide six

distinct curve sizes for varying patient anatomies and procedure locations,

and a comfortable, ergonomic steering mechanism(1).

-- The 150-watt 1500T8 Cardiac Ablation Generator(2) with Remote Control(2),

available in selected international markets, which introduces outstanding

temperature control, versatility, and safety. The remote control console

includes a rotary knob that facilitates parameter selection and adjustment.

Connected via a 20-foot cable, the console allows for remote, simultaneous

operation of the T8 generator and B. Braun Infusomat®(3) Pump, allowing

two-way, pump-to-generator communication. This enhanced system accommodates

the Therapy family of catheters, including the Cool Path Irrigated

Tip Ablation Catheter(2).

St. Jude Medical is dedicated to making life better for cardiac,

neurological and chronic pain patients worldwide through excellence in

medical device technology and services. The company has five major focus

areas that include: cardiac rhythm management, atrial fibrillation, cardiac

surgery, cardiology, and neuromodulation. Headquartered in St. ,

Minnesota, the company employs nearly 10,000 people worldwide. For more

information, please visit www.sjm.com.

Any statements made regarding St. Jude Medical's anticipated future product

launches, regulatory approvals, revenues, earnings, market shares, and

potential clinical success are forward-looking statements which are subject

to risks and uncertainties, such as those described in the Company's

Quarterly Report on Form 10-Q filed on November 8, 2005 (see page 35).

Actual results may differ materially from anticipated results.