Guest guest Posted January 4, 2012 Report Share Posted January 4, 2012 … We conducted a changepoint analysis on transformed CDDS data from 1970 to 1997 (from(7)) and found a changepoint in 1984… Surprisingly, we found similarity in the changepoint years for the CDDS dataset (1988), a Danish dataset(1988), and a worldwide composite dataset (1989) (2), and which was consistent with the timing forincreasing autism in other studiesAs we point out in the paper, while artifacts associated withobserved increases in various studies cannot be ruled out, from a precautionary standpoint, it seemsprudent to assume that at least some portion of the observed increases in incidence is real and resultsfrom the interaction of environmental factors with genetically susceptible populations. Since exposureto environmental factors is potentially preventable, identification of relevant candidate factors shouldbe a research priority. We welcome further examination of the datasets we used and our approaches. E. Mc*, F. National Health and Environmental Effects Research LaboratoryU.S. Environmental Protection AgencyMD-B343-06Research Triangle Park, NC 27711http://pubs.acs.org/doi/full/10.1021/es902057k?prevSearch=%2BE.%2BMc%2Band%2B%2BF.%2B & searchHistoryKey=andhttp://pubs.acs.org/doi/abs/10.1021/es204570a?prevSearch=%2BE.%2BMc%2Band%2B%2BF.%2B & searchHistoryKey= Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2012 Report Share Posted January 8, 2012 Here are the papers, in case people can't access the articles.THANK YOU for sharing.Sylvia … We conducted a changepoint analysis on transformed CDDS data from 1970 to 1997 (from(7)) and found a changepoint in 1984… Surprisingly, we found similarity in the changepoint years for the CDDS dataset (1988), a Danish dataset(1988), and a worldwide composite dataset (1989) (2), and which was consistent with the timing forincreasing autism in other studiesAs we point out in the paper, while artifacts associated withobserved increases in various studies cannot be ruled out, from a precautionary standpoint, it seemsprudent to assume that at least some portion of the observed increases in incidence is real and resultsfrom the interaction of environmental factors with genetically susceptible populations. Since exposureto environmental factors is potentially preventable, identification of relevant candidate factors shouldbe a research priority. We welcome further examination of the datasets we used and our approaches. E. Mc*, F. National Health and Environmental Effects Research LaboratoryU.S. Environmental Protection AgencyMD-B343-06Research Triangle Park, NC 27711http://pubs.acs.org/doi/full/10.1021/es902057k?prevSearch=%2BE.%2BMc%2Band%2B%2BF.%2B & searchHistoryKey=andhttp://pubs.acs.org/doi/abs/10.1021/es204570a?prevSearch=%2BE.%2BMc%2Band%2B%2BF.%2B & searchHistoryKey= 2 of 2 File(s) Timing of ASD-Mc Response.pdf Timing of Increase--EPA Jan 2010.pdf Quote Link to comment Share on other sites More sharing options...
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