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Greetings;

I have recently been asked if I am aware of a " Cool Down " period in CPR and I

believe this may be related to ACLS.

The last I heard of anything is the possibility of sending our patients into

hypothermia during the resuscitation in ACLS.

Is this the same " Cool Down " period or is there another reference I need

more information on?

I know that there is at least a couple of our learned brethren or sisters that

would have information on this. Any and all information is greatly appreciated.

Thank You.

Danny L.

Owner/NREMT-P

PETSAR INC.

(Panhandle Emergency Training Services And Response)

Office

Fax

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Kenny,

If they DO wake up following resuscitation, is induced hypothermia still

recommended?

Gene G.

In a message dated 4/21/08 7:48:51 PM, kenneth.navarro@...

writes:

>

> >>> The last I heard of anything is the possibility of sending our

> patients into hypothermia during the resuscitation in ACLS. <<<

>

> Danny,

>

> In 2 randomized clinical trials, induced hypothermia within minutes

> to hours after ROSC to a temperature between 32°C and 34°C (89.6°F to

> 93.2°F) for 12 to 24 hours) resulted in improved outcome

> in adults who remained comatose after initial resuscitation

> from out-of-hospital ventricular fibrillation (VF) cardiac arrest.

>

> A third study documented improvement in metabolic end points when

> comatose adult patients were cooled after ROSC from out-of-hospital

> cardiac arrest in which the initial rhythm was pulseless electrical

> activity (PEA)/asystole. This study was not designed to measure

> neurological outcome, therefore it is unclear if the observed

> improvement resulted in improved outcome.

>

> The studies used external cooling techniques (eg, cooling blankets

> and frequent applications of ice bags) along with cold saline

> infusions.

>

> Based on this data, the American Heart Association recommends:

>

> Providers should not actively rewarm hemodynamically stable patients

> who spontaneously develop a mild degree of hypothermia (> 33°C

> [91.5F]) after resuscitation from cardiac arrest. (Permissive

> hypothermia - paraphrased - Don't warm them if they get cold on their

> own.)

>

> For the unconscious adult patient with ROSC after out-of-hospital

> cardiac arrest, actively cool to 32°C to 34°C (89.6°F to 93.2°F) for

> 12 to 24 hours when the initial rhythm was VF (Class IIa). (Induced

> hypothermia - paraphrased - If they don't wake up quickly after ROSC,

> cool them down quickly.)

>

> Similar therapy may be beneficial for patients with non-VF arrest out

> of hospital or for in-hospital arrest (Class IIb).

>

> Induced hypothermia following VF is a higher class rating than

> epinephrine, amiodarone, endotracheal intubation, or lidocaine.

>

> Hope this helps.

>

> Kenny Navarro

> UT Southwestern Medical Center at Dallas

>

>

>

**************

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>>> The last I heard of anything is the possibility of sending our

patients into hypothermia during the resuscitation in ACLS. <<<

Danny,

In 2 randomized clinical trials, induced hypothermia within minutes

to hours after ROSC to a temperature between 32°C and 34°C (89.6°F to

93.2°F) for 12 to 24 hours) resulted in improved outcome

in adults who remained comatose after initial resuscitation

from out-of-hospital ventricular fibrillation (VF) cardiac arrest.

A third study documented improvement in metabolic end points when

comatose adult patients were cooled after ROSC from out-of-hospital

cardiac arrest in which the initial rhythm was pulseless electrical

activity (PEA)/asystole. This study was not designed to measure

neurological outcome, therefore it is unclear if the observed

improvement resulted in improved outcome.

The studies used external cooling techniques (eg, cooling blankets

and frequent applications of ice bags) along with cold saline

infusions.

Based on this data, the American Heart Association recommends:

Providers should not actively rewarm hemodynamically stable patients

who spontaneously develop a mild degree of hypothermia (> 33°C

[91.5F]) after resuscitation from cardiac arrest. (Permissive

hypothermia - paraphrased - Don't warm them if they get cold on their

own.)

For the unconscious adult patient with ROSC after out-of-hospital

cardiac arrest, actively cool to 32°C to 34°C (89.6°F to 93.2°F) for

12 to 24 hours when the initial rhythm was VF (Class IIa). (Induced

hypothermia - paraphrased - If they don't wake up quickly after ROSC,

cool them down quickly.)

Similar therapy may be beneficial for patients with non-VF arrest out

of hospital or for in-hospital arrest (Class IIb).

Induced hypothermia following VF is a higher class rating than

epinephrine, amiodarone, endotracheal intubation, or lidocaine.

Hope this helps.

Kenny Navarro

UT Southwestern Medical Center at Dallas

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Guest guest

>>> If they DO wake up following resuscitation, is induced

hypothermia still recommended? <<<

Gene,

Guidelines 2005 do not address sedation and hypothermia for patients

who quickly regain some level of consciousness following ROSC.

Perhaps early cognitive function following ROSC suggests minimal

neurological insult rendering the potential benefits of hypothermia

moot.

However, since guidelines 2005 were published . . .

The French reported the results of a trial of 33 patients cooled

during the resuscitation attempt instead of waiting for ROSC. EMS

administered 2 liters of cold saline by rapid infusion as soon as

possible after obtaining IV access. If ROSC occurred, medics

administered ketamine for sedation and atracurium to prevent

shivering. Twenty (60%) ultimately achieved ROSC and were admitted

to the ICU. Doctors maintained hypothermia for 24 hours before

rewarming. At six months post cardiac arrest, four were still alive

and two had favorable neurological outcomes.

Researchers in Germany have investigated the impact of percutaneous

coronary revascularization (PCI) during therapeutic hypothermia

following cardiac arrest. Doctors induced hypothermia in 31 comatose

patients admitted to the ICU with out-of-hospital cardiac arrest due

to AMI. PCI occurred during the hypothermic state. Researchers

matched the patients to 31 historical controls admitted in the era

prior to hypothermia treatment.

In the hypothermia group, 19 patients were discharged with a

favorable neurological outcome, whereas in controls, such outcome was

observed in only six patients (p=0.002).

Finally, a contraindication to the use of therapeutic hypothermia

after cardiac arrest has always been pregnancy. However, a case

reported in Critical Care Medicine describes a 35-yr-old woman who,

at 13 weeks gestation, had a witnessed out-of-hospital ventricular

fibrillation cardiac arrest. EMS successfully resuscitated the

gravid woman and delivered her comatose to the hospital. The

hospital initiated therapeutic cooling (33°C) for 24 hrs and she was

discharged home with mild neurologic deficit on hospital day 6.

At 39 weeks gestation, delivery of the infant occurred via cesarean

section. APGAR scores were 8 and 9, and neurodevelopmental testing

was appropriate for age at birth and at 2 months.

Kenny Navarro

UT Southwestern Medical Center at Dallas

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Guest guest

Does it seem as if the french do a lot of EMS studies?

LNM

Sent via BlackBerry by AT & T

Re: CPR Question

>>> If they DO wake up following resuscitation, is induced

hypothermia still recommended? <<<

Gene,

Guidelines 2005 do not address sedation and hypothermia for patients

who quickly regain some level of consciousness following ROSC.

Perhaps early cognitive function following ROSC suggests minimal

neurological insult rendering the potential benefits of hypothermia

moot.

However, since guidelines 2005 were published . . .

The French reported the results of a trial of 33 patients cooled

during the resuscitation attempt instead of waiting for ROSC. EMS

administered 2 liters of cold saline by rapid infusion as soon as

possible after obtaining IV access. If ROSC occurred, medics

administered ketamine for sedation and atracurium to prevent

shivering. Twenty (60%) ultimately achieved ROSC and were admitted

to the ICU. Doctors maintained hypothermia for 24 hours before

rewarming. At six months post cardiac arrest, four were still alive

and two had favorable neurological outcomes.

Researchers in Germany have investigated the impact of percutaneous

coronary revascularization (PCI) during therapeutic hypothermia

following cardiac arrest. Doctors induced hypothermia in 31 comatose

patients admitted to the ICU with out-of-hospital cardiac arrest due

to AMI. PCI occurred during the hypothermic state. Researchers

matched the patients to 31 historical controls admitted in the era

prior to hypothermia treatment.

In the hypothermia group, 19 patients were discharged with a

favorable neurological outcome, whereas in controls, such outcome was

observed in only six patients (p=0.002).

Finally, a contraindication to the use of therapeutic hypothermia

after cardiac arrest has always been pregnancy. However, a case

reported in Critical Care Medicine describes a 35-yr-old woman who,

at 13 weeks gestation, had a witnessed out-of-hospital ventricular

fibrillation cardiac arrest. EMS successfully resuscitated the

gravid woman and delivered her comatose to the hospital. The

hospital initiated therapeutic cooling (33°C) for 24 hrs and she was

discharged home with mild neurologic deficit on hospital day 6.

At 39 weeks gestation, delivery of the infant occurred via cesarean

section. APGAR scores were 8 and 9, and neurodevelopmental testing

was appropriate for age at birth and at 2 months.

Kenny Navarro

UT Southwestern Medical Center at Dallas

------------------------------------

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  • 2 weeks later...
Guest guest

Kenny:

I appologize for not thanking you earlier for your input, Thank You.

Is this what is referred to as the " cooling down period " or was there another

reference I am not aware of that pertains to that particular grouping of words?

I was not particularly sure what the indivdual I spoke to was referencing.

This appeared to be the closest I could remember.

Kenny Navarro wrote:

>>> The last I heard of anything is the possibility of sending our

patients into hypothermia during the resuscitation in ACLS. <<<

Danny,

In 2 randomized clinical trials, induced hypothermia within minutes

to hours after ROSC to a temperature between 32°C and 34°C (89.6°F to

93.2°F) for 12 to 24 hours) resulted in improved outcome

in adults who remained comatose after initial resuscitation

from out-of-hospital ventricular fibrillation (VF) cardiac arrest.

A third study documented improvement in metabolic end points when

comatose adult patients were cooled after ROSC from out-of-hospital

cardiac arrest in which the initial rhythm was pulseless electrical

activity (PEA)/asystole. This study was not designed to measure

neurological outcome, therefore it is unclear if the observed

improvement resulted in improved outcome.

The studies used external cooling techniques (eg, cooling blankets

and frequent applications of ice bags) along with cold saline

infusions.

Based on this data, the American Heart Association recommends:

Providers should not actively rewarm hemodynamically stable patients

who spontaneously develop a mild degree of hypothermia (> 33°C

[91.5F]) after resuscitation from cardiac arrest. (Permissive

hypothermia - paraphrased - Don't warm them if they get cold on their

own.)

For the unconscious adult patient with ROSC after out-of-hospital

cardiac arrest, actively cool to 32°C to 34°C (89.6°F to 93.2°F) for

12 to 24 hours when the initial rhythm was VF (Class IIa). (Induced

hypothermia - paraphrased - If they don't wake up quickly after ROSC,

cool them down quickly.)

Similar therapy may be beneficial for patients with non-VF arrest out

of hospital or for in-hospital arrest (Class IIb).

Induced hypothermia following VF is a higher class rating than

epinephrine, amiodarone, endotracheal intubation, or lidocaine.

Hope this helps.

Kenny Navarro

UT Southwestern Medical Center at Dallas

Danny L.

Owner/NREMT-P

PETSAR INC.

(Panhandle Emergency Training Services And Response)

Office

Fax

Link to comment
Share on other sites

Guest guest

>>> Is this what is referred to as the " cooling down period " or was

there another reference I am not aware of that pertains to that

particular grouping of words? I was not particularly sure what the

indivdual I spoke to was referencing. This appeared to be the closest

I could remember.<<<

Danny,

I'm not sure what the term " cooling down period " is meant to imply

during resuscitation. The only thing I am aware of that even closely

resembles cooling in cardiac arrest resuscitation is therapeutic

hypothermia.

Kenny Navarro

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Guest guest

Kenny;

Thank You. I too have only heard of the hypothermia post rescusitation. I was

just making sure I have not missed anything.

Kenny Navarro wrote:

>>> Is this what is referred to as the " cooling down period " or was

there another reference I am not aware of that pertains to that

particular grouping of words? I was not particularly sure what the

indivdual I spoke to was referencing. This appeared to be the closest

I could remember.<<<

Danny,

I'm not sure what the term " cooling down period " is meant to imply

during resuscitation. The only thing I am aware of that even closely

resembles cooling in cardiac arrest resuscitation is therapeutic

hypothermia.

Kenny Navarro

Danny L.

Owner/NREMT-P

PETSAR INC.

(Panhandle Emergency Training Services And Response)

Office

Fax

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