Guest guest Posted September 16, 2011 Report Share Posted September 16, 2011 Try your school OT. Truly, it's not that hard. My son started it when he was 2.5 and you do it the same way you do anything else. You take lots of notes and adjust according to data. My OT tried to follow the protocol as written and turned my son into a psychotic mess. All the other EI therapists were asking the OT what she did to our kid. He couldn't tolerate the cd's with words first at all. We had to start with classical, then move to ease then move to the Jamz discs. Twice a day, 20 minutes each time. Don't do it when driving (car sickness!!! it does affect vestibular system) and don't watch TV or do anything that will interfere with the "listening". The best things to actually do are things like drawing, coloring obstacle courses and such. Things that make you use other skills with the auditory senses (fine motor, gross motor, tactile things, brain games, etc). Or cross-lateral exercises.Just take notes and switch discs if you see negatives and try it again later if you need to. It's really not rocket science. I have the worksheet on it if you'd like it.These are home programs. There are center based programs like Berard and Tomatis. These are much more expensive and intensive programs. We never went to center based because home based worked fantastic. ~Antiviral Therapy 101~ gryffinstail.wordpress.com/ ~~ @Gryffins_Tail ~ Yes. There is a recommended protocol and we started with all the Jamz (named after fruits). Then we moved to Ease and some of the classical CDs like Vivaldi. You really want to find someone who is trained in this because if you do the wrong cd at the wrong time kids can get very disregulated. But it was one of the best/easiest therapies we did. RuthSent from my iPhone So essentially your OT and Speech pathologist suggested you which CDs to buy right?Could you please tell me which CDs (titles) you bought?/ Noel The vital links & samonas are CDs You buy ( along with special headphones) and you can actually do the therapy at home. Both our OT and speech pathologist were certified in the therapy and they recommended the CDs. It is much cheaper than going to a center so that was great for us. RuthSent from my iPhone I am just curious about these Auditory Integration programs. I went through both the sites but I could not find their 'centers' or I wonder if you have to find an OT therapist trained by them. A quick thought was I would take my son to their center for the 'treatment' Could you please explain how you used Therapeutic Listening and Samonas? i.e. with the help of a therapist or you just ordered CDs yourself (but in this case how do you know which one to order? Thanks,Noel I love auditory integration. It was a huge benefit to my son. It also stimulates the vestibular system which is why so many OTs use it. It helps the proprioceptive inputs. It was huge help in not only language (vagus nerve system), but also in self regulation and knowing where his body is in space (vestibular system). Loved it. We used Therepeutic Listening (www.vitallinks.net) and Samonas (still use them at times...). <skullsignatureb & wsepiahandcoloredsmall.png> ~Antiviral Therapy 101~ gryffinstail.wordpress.com/ ~ ~ @Gryffins_Tail ~ It was a listening therapy that improved auditory processing but also stimulated the vagus nerve to make it a stronger force. It isn't secret & the trial is still going on. We did a week of assessments & therapy & we go back for more testing & follow-up in a couple weeks. I'm not sure about gut motility since we r also on zithromax & that is having it's own effects. I am hopeful it will have a positive effect on the immune system. We are definitely seeing less reactivity and aggression ( almost completely gone) and more inclination to discuss and openly express emotion, which is HUGE for my guy. He has had a lot of anger since his regression and used to completely avoid talking about his emotions. He is more connected as well. So, overall good stuff. HTHRuthSent from my iPhone Thanks Ruth! what was the actual treatment (if not a secret still?). Did it have any effect on gut motility? Natasa > > http://www.ccjm.org/content/76/Suppl_2/S86.long > > We just finished a clinical trial on this and are seeing some good results. He is definitely much less reactive and is getting much better at showing and talking about emotion. > > Ruth > > Severity of autism and fear conditioning - VERY interesting > > > > > > > > > Only high-functioning kids studied here. They found that the severity of their autism, esp social functioning, was related to the their fear conditioning (ie with how much fear/anxiety they react to environment). > > This is very interesting because fear conditioning is closely linked to adrenergic/sympathetic system, GABA/glutamate, AND also to levels of histamine and to functioning of serotonin receptors, see below. ( Super interesting and matches our anecdotal experience so far > > > > Better fear conditioning is associated with reduced symptom severity in autism spectrum disorders > > Evidence from behavioral and neuroimaging studies suggest that atypical amygdala function plays a critical role in the development of autism spectrum disorders (ASD). The handful of psychophysiological studies examining amygdala function in ASD using classical fear conditioning paradigms have yielded discordant results. We recorded skin conductance response (SCR) during a simple discrimination conditioning task in 30 children and adolescents (ages 8â€"18) diagnosed with high-functioning ASD and 30 age- and IQ-matched, typically developing controls. SCR response in the ASD group was uniquely and positively associated with social anxiety; and negatively correlated with autism symptom severity, in particular with social functioning. Fear conditioning studies have tremendous potential to aid understanding regarding the amygdale's role in the varied symptom profile of ASD. Our data demonstrate that such studies require careful attention to task-specific factors, including task complexity; and also to contributions of dimensional, within-group factors that contribute to ASD heterogeneity. South M et al, Autism Res2011,4:xxxâ€"xxx . © 2011 http://www.ncbi.nlm.nih.gov/pubmed/21905243 > > > > Novelty-induced arousal enhances memory for cued classical fear conditioning: Interactions between peripheral adrenergic and brainstem glutamatergic systems > > > > ... The findings demonstrate that novelty-induced arousal or increasing sympathetic activity with epinephrine in pre- The development of new associations following learning is mediated in part by increased phosphorylation of cAMP response element binding protein (CREB) and subsequent CRE-mediated gene expression exposed animals enhances memory through adrenergic mechanisms initiated in the periphery and transmitted centrally ... > > ... Autonomic indices of sympathetic activity, including skin conductance, cardiac output, and circulating concentrations of the adrenal hormones corticosterone and epinephrine, are all elevated by presenting humans or animals with novel stimuli or after allowing free exploration in an unfamiliar environment the vagus/NTS complex.... > > ... Findings from study 3 revealed that pre-exposed subjects given epinephrine post-conditioning exhibited a significantly greater percentage of freezing behavior during tone-only presentations on a 48-h retention test than did pre-exposed controls. The epinephrine-induced memory enhancement reflected in a higher percentage of freezing behavior was attenuated by interrupting impulse flow between the vagus nerve and the brainstem by blocking postsynaptic glutamate receptors in the NTS. > > ... arousal-induced changes in peripheral autonomic functioning involving elevated heart rate, increased discharge along vagal nerve fibers, and blood pressure are significantly reduced by blocking peripheral â-adrenergic receptors > > ... Consistent with these findings, experiment 2 showed that blocking glutamate receptors in the NTS with the antagonist CNQX attenuates the memory improvement observed by conditioning animals in an unfamiliar context. ... Findings from this experiment demonstrated that novelty-induced arousal enhancement in memory is attenuated when synaptic communication between vagal afferents and brainstem neurons in the NTS are interrupted. > > ... Overall, findings from experiments 1 and 2 suggest novelty-induced arousal affects mnemonic processes by influencing peripheral hormone release and subsequent activation of the vagal/NTS complex ... Findings from experiment 3 suggest that memory enhancement observed in response to novelty-induced arousal may involve peripheral hormonal secretion. This study demonstrated that increasing peripheral sympathetic output with epinephrine injections significantly enhanced the marginal levels of fear conditioning. > > ... Given the mounting evidence that novelty and peripheral adrenergic mechanisms work in concert to strengthen synaptic connections, the current findings underscore the importance of signaling between the vagus and NTS complex in mediating the beneficial consequences of emotional arousal on memory. http://learnmem.cshlp.org/content/16/10/625.long > > > > then also this: The physiology of brain histamine. > > > ... The central histamine system is involved in many central nervous system functions: arousal; anxiety; activation of the sympathetic nervous system; the stress-related release of hormones from the pituitary and of central aminergic neurotransmitters; antinociception; water retention and suppression of eating. A role for the neuronal histamine system as a danger response system is proposed. http://www.ncbi.nlm.nih.gov/pubmed/11164999 > > The H1- and H2- histamine blockers chlorpheniramine and ranitidine applied to the nucleus basalis magnocellularis region modulate anxiety and reinforcement related processes. > > > http://www.ncbi.nlm.nih.gov/pubmed/9833631 GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors. > > > http://www.ncbi.nlm.nih.gov/pubmed/18477857 D1 and D2 dopaminergic systems in the rat basolateral amygdala are involved in anxiogenic-like effects induced by histamine . > > > http://www.ncbi.nlm.nih.gov/pubmed/21628344 > > 5-HT2- and D1-mechanisms of the basolateral nucleus of the amygdala enhance conditioned fear and impair unconditioned fear . > > > http://www.ncbi.nlm.nih.gov/pubmed/17126419 > > > > The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment > We found that acute administration of the SSRI citalopram enhanced acquisition, whereas chronic treatment reduced the acquisition of auditory fear conditioning . ... Our findings with citalopram are consistent with the clinical effects of SSRI treatment seen in patients with anxiety disorders, in which anxiety is often increased during early stages of treatment and decreased after several weeks of treatment . http://www.ncbi.nlm.nih.gov/pubmed/15184036 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 18, 2011 Report Share Posted September 18, 2011 I'd love to see the worksheet!Thanks CherylSent from my iPhoneTry your school OT. Truly, it's not that hard. My son started it when he was 2.5 and you do it the same way you do anything else. You take lots of notes and adjust according to data. My OT tried to follow the protocol as written and turned my son into a psychotic mess. All the other EI therapists were asking the OT what she did to our kid. He couldn't tolerate the cd's with words first at all. We had to start with classical, then move to ease then move to the Jamz discs. Twice a day, 20 minutes each time. Don't do it when driving (car sickness!!! it does affect vestibular system) and don't watch TV or do anything that will interfere with the "listening". The best things to actually do are things like drawing, coloring obstacle courses and such. Things that make you use other skills with the auditory senses (fine motor, gross motor, tactile things, brain games, etc). Or cross-lateral exercises.Just take notes and switch discs if you see negatives and try it again later if you need to. It's really not rocket science. I have the worksheet on it if you'd like it.These are home programs. There are center based programs like Berard and Tomatis. These are much more expensive and intensive programs. We never went to center based because home based worked fantastic. <skullsignatureb & wsepiahandcoloredsmall.png>~Antiviral Therapy 101~ gryffinstail.wordpress.com/ ~~ @Gryffins_Tail ~ Yes. There is a recommended protocol and we started with all the Jamz (named after fruits). Then we moved to Ease and some of the classical CDs like Vivaldi. You really want to find someone who is trained in this because if you do the wrong cd at the wrong time kids can get very disregulated. But it was one of the best/easiest therapies we did. RuthSent from my iPhone So essentially your OT and Speech pathologist suggested you which CDs to buy right?Could you please tell me which CDs (titles) you bought?/ Noel The vital links & samonas are CDs You buy ( along with special headphones) and you can actually do the therapy at home. Both our OT and speech pathologist were certified in the therapy and they recommended the CDs. It is much cheaper than going to a center so that was great for us. RuthSent from my iPhone I am just curious about these Auditory Integration programs. I went through both the sites but I could not find their 'centers' or I wonder if you have to find an OT therapist trained by them. A quick thought was I would take my son to their center for the 'treatment' Could you please explain how you used Therapeutic Listening and Samonas? i.e. with the help of a therapist or you just ordered CDs yourself (but in this case how do you know which one to order? Thanks,Noel I love auditory integration. It was a huge benefit to my son. It also stimulates the vestibular system which is why so many OTs use it. It helps the proprioceptive inputs. It was huge help in not only language (vagus nerve system), but also in self regulation and knowing where his body is in space (vestibular system). Loved it. We used Therepeutic Listening (www.vitallinks.net) and Samonas (still use them at times...). <skullsignatureb & wsepiahandcoloredsmall.png> ~Antiviral Therapy 101~ gryffinstail.wordpress.com/ ~ ~ @Gryffins_Tail ~ It was a listening therapy that improved auditory processing but also stimulated the vagus nerve to make it a stronger force. It isn't secret & the trial is still going on. We did a week of assessments & therapy & we go back for more testing & follow-up in a couple weeks. I'm not sure about gut motility since we r also on zithromax & that is having it's own effects. I am hopeful it will have a positive effect on the immune system. We are definitely seeing less reactivity and aggression ( almost completely gone) and more inclination to discuss and openly express emotion, which is HUGE for my guy. He has had a lot of anger since his regression and used to completely avoid talking about his emotions. He is more connected as well. So, overall good stuff. HTHRuthSent from my iPhone Thanks Ruth! what was the actual treatment (if not a secret still?). Did it have any effect on gut motility? Natasa > > http://www.ccjm.org/content/76/Suppl_2/S86.long > > We just finished a clinical trial on this and are seeing some good results. He is definitely much less reactive and is getting much better at showing and talking about emotion. > > Ruth > > Severity of autism and fear conditioning - VERY interesting > > > > > > > > > Only high-functioning kids studied here. They found that the severity of their autism, esp social functioning, was related to the their fear conditioning (ie with how much fear/anxiety they react to environment). > > This is very interesting because fear conditioning is closely linked to adrenergic/sympathetic system, GABA/glutamate, AND also to levels of histamine and to functioning of serotonin receptors, see below. ( Super interesting and matches our anecdotal experience so far > > > > Better fear conditioning is associated with reduced symptom severity in autism spectrum disorders > > Evidence from behavioral and neuroimaging studies suggest that atypical amygdala function plays a critical role in the development of autism spectrum disorders (ASD). The handful of psychophysiological studies examining amygdala function in ASD using classical fear conditioning paradigms have yielded discordant results. We recorded skin conductance response (SCR) during a simple discrimination conditioning task in 30 children and adolescents (ages 8â€"18) diagnosed with high-functioning ASD and 30 age- and IQ-matched, typically developing controls. SCR response in the ASD group was uniquely and positively associated with social anxiety; and negatively correlated with autism symptom severity, in particular with social functioning. Fear conditioning studies have tremendous potential to aid understanding regarding the amygdale's role in the varied symptom profile of ASD. Our data demonstrate that such studies require careful attention to task-specific factors, including task complexity; and also to contributions of dimensional, within-group factors that contribute to ASD heterogeneity. South M et al, Autism Res2011,4:xxxâ€"xxx . © 2011 http://www.ncbi.nlm.nih.gov/pubmed/21905243 > > > > Novelty-induced arousal enhances memory for cued classical fear conditioning: Interactions between peripheral adrenergic and brainstem glutamatergic systems > > > > ... The findings demonstrate that novelty-induced arousal or increasing sympathetic activity with epinephrine in pre- The development of new associations following learning is mediated in part by increased phosphorylation of cAMP response element binding protein (CREB) and subsequent CRE-mediated gene expression exposed animals enhances memory through adrenergic mechanisms initiated in the periphery and transmitted centrally ... > > ... Autonomic indices of sympathetic activity, including skin conductance, cardiac output, and circulating concentrations of the adrenal hormones corticosterone and epinephrine, are all elevated by presenting humans or animals with novel stimuli or after allowing free exploration in an unfamiliar environment the vagus/NTS complex.... > > ... Findings from study 3 revealed that pre-exposed subjects given epinephrine post-conditioning exhibited a significantly greater percentage of freezing behavior during tone-only presentations on a 48-h retention test than did pre-exposed controls. The epinephrine-induced memory enhancement reflected in a higher percentage of freezing behavior was attenuated by interrupting impulse flow between the vagus nerve and the brainstem by blocking postsynaptic glutamate receptors in the NTS. > > ... arousal-induced changes in peripheral autonomic functioning involving elevated heart rate, increased discharge along vagal nerve fibers, and blood pressure are significantly reduced by blocking peripheral â-adrenergic receptors > > ... Consistent with these findings, experiment 2 showed that blocking glutamate receptors in the NTS with the antagonist CNQX attenuates the memory improvement observed by conditioning animals in an unfamiliar context. ... Findings from this experiment demonstrated that novelty-induced arousal enhancement in memory is attenuated when synaptic communication between vagal afferents and brainstem neurons in the NTS are interrupted. > > ... Overall, findings from experiments 1 and 2 suggest novelty-induced arousal affects mnemonic processes by influencing peripheral hormone release and subsequent activation of the vagal/NTS complex ... Findings from experiment 3 suggest that memory enhancement observed in response to novelty-induced arousal may involve peripheral hormonal secretion. This study demonstrated that increasing peripheral sympathetic output with epinephrine injections significantly enhanced the marginal levels of fear conditioning. > > ... Given the mounting evidence that novelty and peripheral adrenergic mechanisms work in concert to strengthen synaptic connections, the current findings underscore the importance of signaling between the vagus and NTS complex in mediating the beneficial consequences of emotional arousal on memory. http://learnmem.cshlp.org/content/16/10/625.long > > > > then also this: The physiology of brain histamine. > > > ... The central histamine system is involved in many central nervous system functions: arousal; anxiety; activation of the sympathetic nervous system; the stress-related release of hormones from the pituitary and of central aminergic neurotransmitters; antinociception; water retention and suppression of eating. A role for the neuronal histamine system as a danger response system is proposed. http://www.ncbi.nlm.nih.gov/pubmed/11164999 > > The H1- and H2- histamine blockers chlorpheniramine and ranitidine applied to the nucleus basalis magnocellularis region modulate anxiety and reinforcement related processes. > > > http://www.ncbi.nlm.nih.gov/pubmed/9833631 GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors. > > > http://www.ncbi.nlm.nih.gov/pubmed/18477857 D1 and D2 dopaminergic systems in the rat basolateral amygdala are involved in anxiogenic-like effects induced by histamine . > > > http://www.ncbi.nlm.nih.gov/pubmed/21628344 > > 5-HT2- and D1-mechanisms of the basolateral nucleus of the amygdala enhance conditioned fear and impair unconditioned fear . > > > http://www.ncbi.nlm.nih.gov/pubmed/17126419 > > > > The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment > We found that acute administration of the SSRI citalopram enhanced acquisition, whereas chronic treatment reduced the acquisition of auditory fear conditioning . ... Our findings with citalopram are consistent with the clinical effects of SSRI treatment seen in patients with anxiety disorders, in which anxiety is often increased during early stages of treatment and decreased after several weeks of treatment . http://www.ncbi.nlm.nih.gov/pubmed/15184036 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 18, 2011 Report Share Posted September 18, 2011 Hi brenda . Look up rosalie seymour she is in uk . She has a home versio devised of ait. > Hi Ruth > Pls could u give me the website for the CDs for auditory therapy, it would > be soo helpful. One of the centres here in uk charge £1800 for ten (30 > minutes) session. > > Matambanadzo > > On 16 Sep 2011, at 21:51, Setlak > wrote: > >> The vital links & samonas are CDs You buy ( along with special headphones) >> and you can actually do the therapy at home. Both our OT and speech >> pathologist were certified in the therapy and they recommended the CDs. >> >> It is much cheaper than going to a center so that was great for us. >> >> Ruth >> >> Sent from my iPhone >> >> >> >>> >>> I am just curious about these Auditory Integration programs. I went >>> through both the sites but I could not find their 'centers' or I wonder >>> if you have to find an OT therapist trained by them. A quick thought was >>> I would take my son to their center for the 'treatment' >>> >>> Could you please explain how you used Therapeutic Listening and Samonas? >>> i.e. with the help of a therapist or you just ordered CDs yourself (but >>> in this case how do you know which one to order? >>> >>> Thanks, >>> Noel >>> >>> >>> On Fri, Sep 16, 2011 at 12:33 PM, cheryl biomed.mom >>> wrote: >>> I love auditory integration. It was a huge benefit to my son. It also >>> stimulates the vestibular system which is why so many OTs use it. It >>> helps the proprioceptive inputs. It was huge help in not only language >>> (vagus nerve system), but also in self regulation and knowing where his >>> body is in space (vestibular system). Loved it. We used Therepeutic >>> Listening (www.vitallinks.net) and Samonas (still use them at times...). >>> >>> <skullsignatureb & wsepiahandcoloredsmall.png> >>> ~Antiviral Therapy 101 >>> >>> ~ gryffinstail.wordpress.com/ ~ >>> ~ @Gryffins_Tail ~ >>> >>> >>> >>>> >>>> >>>> It was a listening therapy that improved auditory processing but also >>>> stimulated the vagus nerve to make it a stronger force. It isn't secret >>>> & the trial is still going on. We did a week of assessments & therapy & >>>> we go back for more testing & follow-up in a couple weeks. >>>> >>>> I'm not sure about gut motility since we r also on zithromax & that is >>>> having it's own effects. I am hopeful it will have a positive effect on >>>> the immune system. >>>> >>>> We are definitely seeing less reactivity and aggression ( almost >>>> completely gone) and more inclination to discuss and openly express >>>> emotion, which is HUGE for my guy. He has had a lot of anger since his >>>> regression and used to completely avoid talking about his emotions. He >>>> is more connected as well. So, overall good stuff. >>>> >>>> HTH >>>> >>>> Ruth >>>> >>>> Sent from my iPhone >>>> >>>> On Sep 16, 2011, at 10:09 AM, " natasa778 " >>>> wrote: >>>> >>>>> >>>>> >>>>> Thanks Ruth! what was the actual treatment (if not a secret still?). >>>>> Did >>>>> it have any effect on gut motility? >>>>> >>>>> Natasa >>>>> >>>>> >>>>> > >>>>> > http://www.ccjm.org/content/76/Suppl_2/S86.long >>>>> > >>>>> > We just finished a clinical trial on this and are seeing some good >>>>> results. He is definitely much less reactive and is getting much better >>>>> at showing and talking about emotion. >>>>> > >>>>> > Ruth >>>>> > >>>>> > Severity of autism and fear conditioning - >>>>> > VERY >>>>> interesting >>>>> > >>>>> > >>>>> > >>>>> > >>>>> > >>>>> > >>>>> > >>>>> > >>>>> > Only high-functioning kids studied here. They found that the severity >>>>> of their autism, esp social functioning, was related to the their fear >>>>> conditioning (ie with how much fear/anxiety they react to environment). >>>>> > >>>>> > This is very interesting because fear conditioning is closely linked >>>>> to adrenergic/sympathetic system, GABA/glutamate, AND also to levels of >>>>> histamine and to functioning of serotonin receptors, see below. ( Super >>>>> interesting and matches our anecdotal experience so far >>>>> > >>>>> > >>>>> > >>>>> > Better fear conditioning is associated with reduced symptom severity >>>>> in autism spectrum disorders >>>>> > >>>>> > Evidence from behavioral and neuroimaging studies suggest that >>>>> atypical amygdala function plays a critical role in the development of >>>>> autism spectrum disorders (ASD). The handful of psychophysiological >>>>> studies examining amygdala function in ASD using classical fear >>>>> conditioning paradigms have yielded discordant results. We recorded >>>>> skin >>>>> conductance response (SCR) during a simple discrimination conditioning >>>>> task in 30 children and adolescents (ages 8†" 18) diagnosed with >>>>> high-functioning ASD and 30 age- and IQ-matched, typically developing >>>>> controls. SCR response in the ASD group was uniquely and positively >>>>> associated with social anxiety; and negatively correlated with autism >>>>> symptom severity, in particular with social functioning. Fear >>>>> conditioning studies have tremendous potential to aid understanding >>>>> regarding the amygdale's role in the varied symptom profile of ASD. Our >>>>> data demonstrate that such studies require careful attention to >>>>> task-specific factors, including task complexity; and also to >>>>> contributions of dimensional, within-group factors that contribute to >>>>> ASD heterogeneity. South M et al, Autism Res2011,4:xxx†" xxx . >>>>> © 2011 http://www.ncbi.nlm.nih.gov/pubmed/21905243 >>>>> > >>>>> > >>>>> > >>>>> > Novelty-induced arousal enhances memory for cued classical fear >>>>> conditioning: Interactions between peripheral adrenergic and brainstem >>>>> glutamatergic systems >>>>> > >>>>> > >>>>> > >>>>> > ... The findings demonstrate that novelty-induced arousal or >>>>> increasing sympathetic activity with epinephrine in pre- The >>>>> development >>>>> of new associations following learning is mediated in part by increased >>>>> phosphorylation of cAMP response element binding protein (CREB) and >>>>> subsequent CRE-mediated gene expression exposed animals enhances memory >>>>> through adrenergic mechanisms initiated in the periphery and >>>>> transmitted >>>>> centrally ... >>>>> > >>>>> > ... Autonomic indices of sympathetic activity, including skin >>>>> conductance, cardiac output, and circulating concentrations of the >>>>> adrenal hormones corticosterone and epinephrine, are all elevated by >>>>> presenting humans or animals with novel stimuli or after allowing free >>>>> exploration in an unfamiliar environment the vagus/NTS complex.... >>>>> > >>>>> > ... Findings from study 3 revealed that pre-exposed subjects given >>>>> epinephrine post-conditioning exhibited a significantly greater >>>>> percentage of freezing behavior during tone-only presentations on a >>>>> 48-h >>>>> retention test than did pre-exposed controls. The epinephrine-induced >>>>> memory enhancement reflected in a higher percentage of freezing >>>>> behavior >>>>> was attenuated by interrupting impulse flow between the vagus nerve and >>>>> the brainstem by blocking postsynaptic glutamate receptors in the NTS. >>>>> > >>>>> > ... arousal-induced changes in peripheral autonomic functioning >>>>> involving elevated heart rate, increased discharge along vagal nerve >>>>> fibers, and blood pressure are significantly reduced by blocking >>>>> peripheral â-adrenergic receptors >>>>> > >>>>> > ... Consistent with these findings, experiment 2 showed that blocking >>>>> glutamate receptors in the NTS with the antagonist CNQX attenuates the >>>>> memory improvement observed by conditioning animals in an unfamiliar >>>>> context. ... Findings from this experiment demonstrated that >>>>> novelty-induced arousal enhancement in memory is attenuated when >>>>> synaptic communication between vagal afferents and brainstem neurons in >>>>> the NTS are interrupted. >>>>> > >>>>> > ... Overall, findings from experiments 1 and 2 suggest >>>>> > novelty-induced >>>>> arousal affects mnemonic processes by influencing peripheral hormone >>>>> release and subsequent activation of the vagal/NTS complex ... Findings >>>>> from experiment 3 suggest that memory enhancement observed in response >>>>> to novelty-induced arousal may involve peripheral hormonal secretion. >>>>> This study demonstrated that increasing peripheral sympathetic output >>>>> with epinephrine injections significantly enhanced the marginal levels >>>>> of fear conditioning. >>>>> > >>>>> > ... Given the mounting evidence that novelty and peripheral >>>>> > adrenergic >>>>> mechanisms work in concert to strengthen synaptic connections, the >>>>> current findings underscore the importance of signaling between the >>>>> vagus and NTS complex in mediating the beneficial consequences of >>>>> emotional arousal on memory. >>>>> http://learnmem.cshlp.org/content/16/10/625.long >>>>> > >>>>> > >>>>> > >>>>> > then also this: The physiology of brain histamine. >>>>> > >>>>> > >>>>> > ... The central histamine system is involved in many central nervous >>>>> system functions: arousal; anxiety; activation of the sympathetic >>>>> nervous system; the stress-related release of hormones from the >>>>> pituitary and of central aminergic neurotransmitters; antinociception; >>>>> water retention and suppression of eating. A role for the neuronal >>>>> histamine system as a danger response system is proposed. >>>>> http://www.ncbi.nlm.nih.gov/pubmed/11164999 >>>>> > >>>>> > The H1- and H2- histamine blockers chlorpheniramine and ranitidine >>>>> applied to the nucleus basalis magnocellularis region modulate anxiety >>>>> and reinforcement related processes. >>>>> > >>>>> > >>>>> > http://www.ncbi.nlm.nih.gov/pubmed/9833631 GABA and histamine >>>>> interaction in the basolateral amygdala of rats in the plus-maze test >>>>> of >>>>> anxiety-like behaviors. >>>>> > >>>>> > >>>>> > http://www.ncbi.nlm.nih.gov/pubmed/18477857 D1 and D2 dopaminergic >>>>> systems in the rat basolateral amygdala are involved in anxiogenic-like >>>>> effects induced by histamine . >>>>> > >>>>> > >>>>> > http://www.ncbi.nlm.nih.gov/pubmed/21628344 >>>>> > >>>>> > 5-HT2- and D1-mechanisms of the basolateral nucleus of the amygdala >>>>> enhance conditioned fear and impair unconditioned fear . >>>>> > >>>>> > >>>>> > http://www.ncbi.nlm.nih.gov/pubmed/17126419 >>>>> > >>>>> > >>>>> > >>>>> > The selective serotonin reuptake inhibitor citalopram increases fear >>>>> after acute treatment but reduces fear with chronic treatment >>>>> > We found that acute administration of the SSRI citalopram enhanced >>>>> acquisition, whereas chronic treatment reduced the acquisition of >>>>> auditory fear conditioning . ... Our findings with citalopram are >>>>> consistent with the clinical effects of SSRI treatment seen in patients >>>>> with anxiety disorders, in which anxiety is often increased during >>>>> early >>>>> stages of treatment and decreased after several weeks of treatment . >>>>> http://www.ncbi.nlm.nih.gov/pubmed/15184036 >>>>> > >>>>> >>>> >>> >>> >> >> > -- Cotter 4 Pollerton Manor Carlow 059 9134964 087 2637921 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 18, 2011 Report Share Posted September 18, 2011 Thank you sooo much I will look her up this evening and feedback to you, be blessed Matambanadzo > Hi brenda . Look up rosalie seymour she is in uk . She has a home > versio devised of ait. > > >> Hi Ruth >> Pls could u give me the website for the CDs for auditory therapy, it would >> be soo helpful. One of the centres here in uk charge £1800 for ten (30 >> minutes) session. >> >> Matambanadzo >> >> On 16 Sep 2011, at 21:51, Setlak >> wrote: >> >>> The vital links & samonas are CDs You buy ( along with special headphones) >>> and you can actually do the therapy at home. Both our OT and speech >>> pathologist were certified in the therapy and they recommended the CDs. >>> >>> It is much cheaper than going to a center so that was great for us. >>> >>> Ruth >>> >>> Sent from my iPhone >>> >>> >>> >>>> >>>> I am just curious about these Auditory Integration programs. I went >>>> through both the sites but I could not find their 'centers' or I wonder >>>> if you have to find an OT therapist trained by them. A quick thought was >>>> I would take my son to their center for the 'treatment' >>>> >>>> Could you please explain how you used Therapeutic Listening and Samonas? >>>> i.e. with the help of a therapist or you just ordered CDs yourself (but >>>> in this case how do you know which one to order? >>>> >>>> Thanks, >>>> Noel >>>> >>>> >>>> On Fri, Sep 16, 2011 at 12:33 PM, cheryl biomed.mom >>>> wrote: >>>> I love auditory integration. It was a huge benefit to my son. It also >>>> stimulates the vestibular system which is why so many OTs use it. It >>>> helps the proprioceptive inputs. It was huge help in not only language >>>> (vagus nerve system), but also in self regulation and knowing where his >>>> body is in space (vestibular system). Loved it. We used Therepeutic >>>> Listening (www.vitallinks.net) and Samonas (still use them at times...). >>>> >>>> <skullsignatureb & wsepiahandcoloredsmall.png> >>>> ~Antiviral Therapy 101 >>>> >>>> ~ gryffinstail.wordpress.com/ ~ >>>> ~ @Gryffins_Tail ~ >>>> >>>> >>>> >>>>> >>>>> >>>>> It was a listening therapy that improved auditory processing but also >>>>> stimulated the vagus nerve to make it a stronger force. It isn't secret >>>>> & the trial is still going on. We did a week of assessments & therapy & >>>>> we go back for more testing & follow-up in a couple weeks. >>>>> >>>>> I'm not sure about gut motility since we r also on zithromax & that is >>>>> having it's own effects. I am hopeful it will have a positive effect on >>>>> the immune system. >>>>> >>>>> We are definitely seeing less reactivity and aggression ( almost >>>>> completely gone) and more inclination to discuss and openly express >>>>> emotion, which is HUGE for my guy. He has had a lot of anger since his >>>>> regression and used to completely avoid talking about his emotions. He >>>>> is more connected as well. So, overall good stuff. >>>>> >>>>> HTH >>>>> >>>>> Ruth >>>>> >>>>> Sent from my iPhone >>>>> >>>>> On Sep 16, 2011, at 10:09 AM, " natasa778 " >>>>> wrote: >>>>> >>>>>> >>>>>> >>>>>> Thanks Ruth! what was the actual treatment (if not a secret still?). >>>>>> Did >>>>>> it have any effect on gut motility? >>>>>> >>>>>> Natasa >>>>>> >>>>>> >>>>>>> >>>>>>> http://www.ccjm.org/content/76/Suppl_2/S86.long >>>>>>> >>>>>>> We just finished a clinical trial on this and are seeing some good >>>>>> results. He is definitely much less reactive and is getting much better >>>>>> at showing and talking about emotion. >>>>>>> >>>>>>> Ruth >>>>>>> >>>>>>> Severity of autism and fear conditioning - >>>>>>> VERY >>>>>> interesting >>>>>>> >>>>>>> >>>>>>> >>>>>>> >>>>>>> >>>>>>> >>>>>>> >>>>>>> >>>>>>> Only high-functioning kids studied here. They found that the severity >>>>>> of their autism, esp social functioning, was related to the their fear >>>>>> conditioning (ie with how much fear/anxiety they react to environment). >>>>>>> >>>>>>> This is very interesting because fear conditioning is closely linked >>>>>> to adrenergic/sympathetic system, GABA/glutamate, AND also to levels of >>>>>> histamine and to functioning of serotonin receptors, see below. ( Super >>>>>> interesting and matches our anecdotal experience so far >>>>>>> >>>>>>> >>>>>>> >>>>>>> Better fear conditioning is associated with reduced symptom severity >>>>>> in autism spectrum disorders >>>>>>> >>>>>>> Evidence from behavioral and neuroimaging studies suggest that >>>>>> atypical amygdala function plays a critical role in the development of >>>>>> autism spectrum disorders (ASD). The handful of psychophysiological >>>>>> studies examining amygdala function in ASD using classical fear >>>>>> conditioning paradigms have yielded discordant results. We recorded >>>>>> skin >>>>>> conductance response (SCR) during a simple discrimination conditioning >>>>>> task in 30 children and adolescents (ages 8†" 18) diagnosed with >>>>>> high-functioning ASD and 30 age- and IQ-matched, typically developing >>>>>> controls. SCR response in the ASD group was uniquely and positively >>>>>> associated with social anxiety; and negatively correlated with autism >>>>>> symptom severity, in particular with social functioning. Fear >>>>>> conditioning studies have tremendous potential to aid understanding >>>>>> regarding the amygdale's role in the varied symptom profile of ASD. Our >>>>>> data demonstrate that such studies require careful attention to >>>>>> task-specific factors, including task complexity; and also to >>>>>> contributions of dimensional, within-group factors that contribute to >>>>>> ASD heterogeneity. South M et al, Autism Res2011,4:xxx†" xxx . >>>>>> © 2011 http://www.ncbi.nlm.nih.gov/pubmed/21905243 >>>>>>> >>>>>>> >>>>>>> >>>>>>> Novelty-induced arousal enhances memory for cued classical fear >>>>>> conditioning: Interactions between peripheral adrenergic and brainstem >>>>>> glutamatergic systems >>>>>>> >>>>>>> >>>>>>> >>>>>>> ... The findings demonstrate that novelty-induced arousal or >>>>>> increasing sympathetic activity with epinephrine in pre- The >>>>>> development >>>>>> of new associations following learning is mediated in part by increased >>>>>> phosphorylation of cAMP response element binding protein (CREB) and >>>>>> subsequent CRE-mediated gene expression exposed animals enhances memory >>>>>> through adrenergic mechanisms initiated in the periphery and >>>>>> transmitted >>>>>> centrally ... >>>>>>> >>>>>>> ... Autonomic indices of sympathetic activity, including skin >>>>>> conductance, cardiac output, and circulating concentrations of the >>>>>> adrenal hormones corticosterone and epinephrine, are all elevated by >>>>>> presenting humans or animals with novel stimuli or after allowing free >>>>>> exploration in an unfamiliar environment the vagus/NTS complex.... >>>>>>> >>>>>>> ... Findings from study 3 revealed that pre-exposed subjects given >>>>>> epinephrine post-conditioning exhibited a significantly greater >>>>>> percentage of freezing behavior during tone-only presentations on a >>>>>> 48-h >>>>>> retention test than did pre-exposed controls. The epinephrine-induced >>>>>> memory enhancement reflected in a higher percentage of freezing >>>>>> behavior >>>>>> was attenuated by interrupting impulse flow between the vagus nerve and >>>>>> the brainstem by blocking postsynaptic glutamate receptors in the NTS. >>>>>>> >>>>>>> ... arousal-induced changes in peripheral autonomic functioning >>>>>> involving elevated heart rate, increased discharge along vagal nerve >>>>>> fibers, and blood pressure are significantly reduced by blocking >>>>>> peripheral â-adrenergic receptors >>>>>>> >>>>>>> ... Consistent with these findings, experiment 2 showed that blocking >>>>>> glutamate receptors in the NTS with the antagonist CNQX attenuates the >>>>>> memory improvement observed by conditioning animals in an unfamiliar >>>>>> context. ... Findings from this experiment demonstrated that >>>>>> novelty-induced arousal enhancement in memory is attenuated when >>>>>> synaptic communication between vagal afferents and brainstem neurons in >>>>>> the NTS are interrupted. >>>>>>> >>>>>>> ... Overall, findings from experiments 1 and 2 suggest >>>>>>> novelty-induced >>>>>> arousal affects mnemonic processes by influencing peripheral hormone >>>>>> release and subsequent activation of the vagal/NTS complex ... Findings >>>>>> from experiment 3 suggest that memory enhancement observed in response >>>>>> to novelty-induced arousal may involve peripheral hormonal secretion. >>>>>> This study demonstrated that increasing peripheral sympathetic output >>>>>> with epinephrine injections significantly enhanced the marginal levels >>>>>> of fear conditioning. >>>>>>> >>>>>>> ... Given the mounting evidence that novelty and peripheral >>>>>>> adrenergic >>>>>> mechanisms work in concert to strengthen synaptic connections, the >>>>>> current findings underscore the importance of signaling between the >>>>>> vagus and NTS complex in mediating the beneficial consequences of >>>>>> emotional arousal on memory. >>>>>> http://learnmem.cshlp.org/content/16/10/625.long >>>>>>> >>>>>>> >>>>>>> >>>>>>> then also this: The physiology of brain histamine. >>>>>>> >>>>>>> >>>>>>> ... The central histamine system is involved in many central nervous >>>>>> system functions: arousal; anxiety; activation of the sympathetic >>>>>> nervous system; the stress-related release of hormones from the >>>>>> pituitary and of central aminergic neurotransmitters; antinociception; >>>>>> water retention and suppression of eating. A role for the neuronal >>>>>> histamine system as a danger response system is proposed. >>>>>> http://www.ncbi.nlm.nih.gov/pubmed/11164999 >>>>>>> >>>>>>> The H1- and H2- histamine blockers chlorpheniramine and ranitidine >>>>>> applied to the nucleus basalis magnocellularis region modulate anxiety >>>>>> and reinforcement related processes. >>>>>>> >>>>>>> >>>>>>> http://www.ncbi.nlm.nih.gov/pubmed/9833631 GABA and histamine >>>>>> interaction in the basolateral amygdala of rats in the plus-maze test >>>>>> of >>>>>> anxiety-like behaviors. >>>>>>> >>>>>>> >>>>>>> http://www.ncbi.nlm.nih.gov/pubmed/18477857 D1 and D2 dopaminergic >>>>>> systems in the rat basolateral amygdala are involved in anxiogenic-like >>>>>> effects induced by histamine . >>>>>>> >>>>>>> >>>>>>> http://www.ncbi.nlm.nih.gov/pubmed/21628344 >>>>>>> >>>>>>> 5-HT2- and D1-mechanisms of the basolateral nucleus of the amygdala >>>>>> enhance conditioned fear and impair unconditioned fear . >>>>>>> >>>>>>> >>>>>>> http://www.ncbi.nlm.nih.gov/pubmed/17126419 >>>>>>> >>>>>>> >>>>>>> >>>>>>> The selective serotonin reuptake inhibitor citalopram increases fear >>>>>> after acute treatment but reduces fear with chronic treatment >>>>>>> We found that acute administration of the SSRI citalopram enhanced >>>>>> acquisition, whereas chronic treatment reduced the acquisition of >>>>>> auditory fear conditioning . ... Our findings with citalopram are >>>>>> consistent with the clinical effects of SSRI treatment seen in patients >>>>>> with anxiety disorders, in which anxiety is often increased during >>>>>> early >>>>>> stages of treatment and decreased after several weeks of treatment . >>>>>> http://www.ncbi.nlm.nih.gov/pubmed/15184036 >>>>>>> >>>>>> >>>>> >>>> >>>> >>> >>> >> > > > -- > Cotter > 4 Pollerton Manor > Carlow > 059 9134964 > 087 2637921 > > > ------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
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