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propolis for anxiety?

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a post on another list prompted me to look into propolis supplementation

again (has been on my list of things to try for a long time, but never got round to it?). According to research in labs it is also a mast cell blocker, inhibits histamine and reduces allergies in mice, powerful anti-inflammatory and antioxidant... Has anyone here tried it?Hum Exp Toxicol. 2011 Jun 14. [Epub ahead of print]Therapeutic effects of propolis essential oil on anxiety of restraint stress mice.Li YJ, X HZ, Shou QY, Zhan ZG, Lu X, Hu FL. College of Animal Science, Zhejiang University, Hangzhou, China.Propolis

has a broad spectrum of biological activities; however, whether its essential oils have neuroprotective effects is unknown. In this study, we found that propolis essential oil (PEO) could significantly reverse the anxiety-like behavior of restraint-stressed mice, and has no effect on locomotor activity. Furthermore, PEO significantly decreased the plasma levels of cortisol (CORT), adrenocorticotropic hormone (ACTH) and

malondialdehyde (MDA), whereas it increased the activity of superoxide dismutase (SOD) in restraint-stressed mice.

These results strongly suggest that PEO has therapeutic effects on anxiety through antagonizing the hyperfunction of hypothalamic-pituitary-adrenal (HPA) axis and improving the ability of antioxidation in brain tissue.

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