Anti-inflammatories helping with OCD/separation anxiety symptoms

May 17, 2012

Something interesting about my son I just noticed that I thought I'd

put out there. Back in the fall, his OCD/separation anxiety behaviors

were pretty bad. He's 3.5 and sometimes gets into the bouts of

separation anxiety with his dad. We ran a CBC in January, and he

showed some indications of inflammation, so I started him on some

Advil for a few days. Interestingly, his separation anxiety/OCD with

his dad subsided.

Last few days...it was really, really bad. His dad couldn't even walk

out of the same room as him without him throwing a total fit. He'd

scream this bloodcurdling scream like we were skinning him alive and

then he'd run after his dad, even when his dad was just 6 feet away in

the bathroom. My son was pounding at the bathroom door, screaming

that screeching scream, stomping his feet on the bathroom door. His

dad had gone out the front door to the car for a minute, still within

sight of Ethan, the storm door was closed but it's glass and Ethan

could still see him...and Ethan broke the metal latch right off the

door -- that's how bad this tantrum/screaming was.

I thought PANDAS both times. I did start him on a bit of inositol

today but I gave him some Advil this morning. Last time, I didn't

think of starting him on inositol. We pulled ASO titers and while we

were waiting for them to come back, I put him on anti-inflammatories

(just Children's Advil) for a week and the separation anxiety came to

a grinding halt.

This time, I'm seeing the same thing. Even in the first 24 hours on

anti-inflammatories, he stopped going apesh*t when his dad left the

room. Seems a lot happier and although he did go and look for his dad

after his dad was gone for 5 minutes, he didn't go frantic.

I almost think now it might be inflammation causing this behavior.

Has anyone else seen this correlate with inflammation? This behavior

seems to be responding to anti-inflammatories for him. I wonder

what's causing the inflammation?

May 17, 2012

Alberta, have you ever herd of " stop calling it autism " ? They have a website and

I was reading their protocol a few days ago and they were talking about

inflammation and How using NSAIDs helps a lot of kids. Looks like you are on to

something. Glad your son is feeling better:)

May 17, 2012

Alberta,

The likely suspects: bacteria, metals, viral. Pick a combination, any combination <sigh>

So this seperation anxiety comes and goes? Do you think it would be a permenant thing if you didnt give the ibu?

The SCIA panel is pretty comprehensive. If you can get it covered, it might give you decent pic of whats going on. Make sure he's getting probiotics to support his belly if he's getting regular doses of ibuprofen.

You know I'm a HUGE antioxident fan. Up his A, C, E. C got us past our toughest days (idk if you need to watch oxalates with him). Get him out in the sun!

Hope you guys are able to figure it out....that is so draining.

Tammy

Sent from my Kindle Fire

May 17, 2012

Alberta,

It seems like you are describing my son. Recently, my son had an acute episode

of anxiety, frequent urination, mood swings, tics and we diagnosed him with

PANS/PANDAS- his ASO and DnaseB titers were negative along with throat swab. In

his case, this was possibly caused by mycoplasma or other gut bug or some other

virus. We did a 4 week course of azithromycin and now have him on prophylaxis

once a week. But what worked for him is advil. The symptoms of pans/pandas are

caused by inflammation. So yes it makes sense that we have to use

antiinflammatories to reduce inflammation. When I looked back, my son had

several similar episodes when he was your son's age. At that time, we were new

to autism and thought that it was just part of autism. Now I realize that my son

fits the picture of episodic nature of PANS. I am not satisfied with zithromax

and will probably be switching to augmentin. Our dan actually recommended 400 mg

of ibuprofen three times a day but I was too chicken to use it at that dose. I

was just using once daily dose of 300 mg. My son has acid reflux and when our

dan tried celebrex for him, he developed gastritis. So now I have him on pepcid

and back on once daily dose of advil. I had stopped advil three weeks ago as it

was not really doing much anymore. Now that he got another cold, his anxiety was

getting bad again and I gave him advil again and he did wonderful at school. So

I agree with you that we are dealing with inflammation here. I tried curcumin

which gave me results but only for the first few days. After that my son

couldn't take it because of phenol sensitivity. Most of the naturals are

phenolics and my son cannot tolerate them especially during this allergy season.

I am not sure if there are any good pandas docs in Canada but it is worth

exploring that. There are a couple of good ones here but so far I havn't found

anyone who takes our insurance. I have an appointment coming up soon with our

dan and will discuss the treatment plan for pandas in depth. I will share with

you whatever I learn. I joined the pandas autism group also which is a good

avenue to learn more about pandas/pans. I really think that in your son's case,

he is dealing with pandas/pans. Consider using antibiotics for a few days

depending on what you think is the source. Can you share what you know about

inositol and how is it supposed to help with anxiety?

Thanks

is

>

> Something interesting about my son I just noticed that I thought I'd

> put out there. Back in the fall, his OCD/separation anxiety behaviors

> were pretty bad. He's 3.5 and sometimes gets into the bouts of

> separation anxiety with his dad. We ran a CBC in January, and he

> showed some indications of inflammation, so I started him on some

> Advil for a few days. Interestingly, his separation anxiety/OCD with

> his dad subsided.

>

> Last few days...it was really, really bad. His dad couldn't even walk

> out of the same room as him without him throwing a total fit. He'd

> scream this bloodcurdling scream like we were skinning him alive and

> then he'd run after his dad, even when his dad was just 6 feet away in

> the bathroom. My son was pounding at the bathroom door, screaming

> that screeching scream, stomping his feet on the bathroom door. His

> dad had gone out the front door to the car for a minute, still within

> sight of Ethan, the storm door was closed but it's glass and Ethan

> could still see him...and Ethan broke the metal latch right off the

> door -- that's how bad this tantrum/screaming was.

>

> I thought PANDAS both times. I did start him on a bit of inositol

> today but I gave him some Advil this morning. Last time, I didn't

> think of starting him on inositol. We pulled ASO titers and while we

> were waiting for them to come back, I put him on anti-inflammatories

> (just Children's Advil) for a week and the separation anxiety came to

> a grinding halt.

>

> This time, I'm seeing the same thing. Even in the first 24 hours on

> anti-inflammatories, he stopped going apesh*t when his dad left the

> room. Seems a lot happier and although he did go and look for his dad

> after his dad was gone for 5 minutes, he didn't go frantic.

>

> I almost think now it might be inflammation causing this behavior.

> Has anyone else seen this correlate with inflammation? This behavior

> seems to be responding to anti-inflammatories for him. I wonder

> what's causing the inflammation?

>

May 17, 2012

Inositol supports the b3 in the system. Don't get me started on b3...such an important Vit. So much of the immune system requires niacin. Secondly, inositol modulates serotonin. Got some funky things going on with bacteria and such? Ever notice how in those kids, pathways that require redox reactions from products of niacin metabolism (NAD-NADH) are also affected too? Niacin also shares the tryptophan pathway with the serotonin pathway. Tryptophan either makes quinolinic to make niacin or tryptophan makes serotonin.

I might try Ethan on Lutimax. I hesitated to before bc...well, it's just so damn expensive and for a while when I was working on a pretty big project, I was so broke and literally living on my last hundred bucks. $75 bucks was pretty steep for me then. But I just got paid for a few projects so I might splurge and try Lutimax. I'm not convinced it's PANDAS or PANS. I know that ASO titers don't mean a whole lot but we pulled them at the height of his last OCD period in January and it just didn't show strep. But what does seem to be a precursor to each " episode " is a cold or flu or allergies, which are activating the immune system. He had a head shaking like tic in january 2011 for months...but that too was eliminated with anti-inflammatories alone. It more looks like an issue of inflammation with him than an actual infection. I reserve the right to be wrong abt this but each time, it really looks like I'm able to nix it with an anti-inflammatory. Could it be that when the inflammation goes on for too long, then it turns into an autoimmune condition like PANS or PANDAS, I wonder? I just don't know...

Meanwhile, Maia is unloading parasites like crazy right now. All kinds of worm eggs and worms are coming out in her stools when I started up Cell Food again for her. Both times when she used cell food for any length of time, I'd start seeing these whitish yellowish ball-like things come out in her stool. I didn't know what they were for the longest time. We just finished an ALA round last weekend but we were using cell food before the round and just as we finished our round, she began these really loose stools with those whitish chunks coming out again and then today, you wouldn't believe how many dead worms I saw in her poop!!! Most were abt 2 cm long and the width of a thread, but several bigger ones came out today with the biggest ones being abt 10 cm and you could DEFINITELY tell those were worms. I'm starting to really believe that there is a correlation with minerals and parasites. Cell Food is definitely not the best way to do it bc of how little you get and the cost of it. 100% I'm going to order a bottle of MMS tonight. And I'm going to talk to our DAN abt implementing the klinghardt parasite protocol and I'm going to do the MMS protocol. I wanna kick the snot outta those parasite f***ers.

Alberta,

It seems like you are describing my son. Recently, my son had an acute episode of anxiety, frequent urination, mood swings, tics and we diagnosed him with PANS/PANDAS- his ASO and DnaseB titers were negative along with throat swab. In his case, this was possibly caused by mycoplasma or other gut bug or some other virus. We did a 4 week course of azithromycin and now have him on prophylaxis once a week. But what worked for him is advil. The symptoms of pans/pandas are caused by inflammation. So yes it makes sense that we have to use antiinflammatories to reduce inflammation. When I looked back, my son had several similar episodes when he was your son's age. At that time, we were new to autism and thought that it was just part of autism. Now I realize that my son fits the picture of episodic nature of PANS. I am not satisfied with zithromax and will probably be switching to augmentin. Our dan actually recommended 400 mg of ibuprofen three times a day but I was too chicken to use it at that dose. I was just using once daily dose of 300 mg. My son has acid reflux and when our dan tried celebrex for him, he developed gastritis. So now I have him on pepcid and back on once daily dose of advil. I had stopped advil three weeks ago as it was not really doing much anymore. Now that he got another cold, his anxiety was getting bad again and I gave him advil again and he did wonderful at school. So I agree with you that we are dealing with inflammation here. I tried curcumin which gave me results but only for the first few days. After that my son couldn't take it because of phenol sensitivity. Most of the naturals are phenolics and my son cannot tolerate them especially during this allergy season. I am not sure if there are any good pandas docs in Canada but it is worth exploring that. There are a couple of good ones here but so far I havn't found anyone who takes our insurance. I have an appointment coming up soon with our dan and will discuss the treatment plan for pandas in depth. I will share with you whatever I learn. I joined the pandas autism group also which is a good avenue to learn more about pandas/pans. I really think that in your son's case, he is dealing with pandas/pans. Consider using antibiotics for a few days depending on what you think is the source. Can you share what you know about inositol and how is it supposed to help with anxiety?