Guest guest Posted April 15, 2008 Report Share Posted April 15, 2008 All, My vulvodynia and vestibulodynia are both well controlled by Imipramine. My daily dosage is 35 mg. However, I've got a real issue with Imipramine - it has increased my resting heart rate to ~85 bpm. It also jacks my heart rate way up when I engage in aerobic activities. This is not a good thing and severally limits what I can do - stairs can be a real challenge. I was curious - has anyone had success with topical tricyclics? Thanks, Steph Quote Link to comment Share on other sites More sharing options...
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