'CAINES' ?? EMLA or ELA-Max???

[Guest guest]

HI all... seeing the EMLA cream mentioned and soooo glad that worked so well for you nne. I knew it was one of the 'caines' as I think someone asked what it was and from what I remember it's a combination of lidocaine & prilocaine together, but wondering if anyone has tried ELA-Max?

It's a newer 'caine' out there and supposedly much better than EMLA or other 'caines' so some physicians say. Here's one abstract. But I also added a few other pieces below (4) on the 'caines' as I found them together in my own files. (which I thought I lost *grin*)

Dee~

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1.

Title: Study on the efficacy of ELA-Max (4% liposomal lidocaine) compared with EMLA cream (eutectic mixture of local anesthetics) using thermosensory threshold analysis in adult volunteers

Author(s): MBY Tang ; ATJ Goon ; CL Goh

Source: Journal of Dermatological Treatment Volume: 15 Number: 2 Page: 84 -- 87

DOI: 10.1080/09546630310018491

Publisher: Dunitz, part of & Francis Health Sciences

Abstract: BACKGROUND: ELA-Max and EMLA cream are topical anesthetics that have been shown to have similar anesthetic efficacy in previous studies.

OBJECTIVE: To evaluate the analgesic efficacy of ELA-Max in comparison with EMLA cream using a novel method of thermosensory threshold analysis.

METHODS: A thermosensory analyzer was used to assess warmth- and heat-induced pain thresholds.

RESULTS: No statistically significant difference was found in pain thresholds using either formulation. However, EMLA cream increased the heat-induced pain threshold to a greater extent than ELA-Max. Thermosensory measurement and analysis was well tolerated and no adverse events were encountered.

CONCLUSIONS: EMLA cream may be superior to ELA-Max for heat-induced pain. This study suggests that thermosensory measurement may be another suitable tool for future topical anesthetic efficacy studies.

© Journal of Dermatological Treatment 2004

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2. (NO idea of when this was written or if EMLA was taken off the market then brought back as he suggests here) Dee

I am a gynecologist and on several of the V. groups, Due to the voluminous numbers of messages on the message board, I can't keep up with all of the correspondence that occurs but I do try to pay attention to the overall themes that occur at the vulvodynia group site...

My purpose at this site is not to advance my personal practice, but to try and inform people of the knowledge I've acquired over the past ten years that I've been treating this condition. I've found this condition very challenging to treat in some patients at times, and at times, very easy to eliminate and treat. I am not a researcher; I am a clinical practitioner with some very rewarding success stories over the years.At any rate, in response to the use of Lidocaine to facilitate sexual intercourse, I have not personally found this treatment satisfying for the majority of women with dysesthetic vulvodynia.

However, the use of 3.5% prilocaine (EMLA cream) applied to the introitus of the vagina and any sensitive areas of the vulva works wonders for the majority of women.

Unfortunately, EMLA was taken off the market by the manufacturer about two years ago and was to be reformulated and placed back on the market. I've never really gotten a good answer as to why (it's safe) and I've also never gotten a good answer as to when it will return to the market.

In the meantime, I've had compounding pharmacists make this preparation for me for the past two years.

I have women apply EMLA to the vulva and introitus of the vagina about one hour prior to attempted intercourse and it will numb these tissues allowing penetration.

Note that it will also numb the clitoris so pay attention to where it's applied unless you also have clitoral area vulvodynia. Also, some patients experience burning at the initial application (especially those with chronic vulvitis) but I've only had two women who absolutely cannot use EMLA due to burning but they did well using topical 20% benzocaine. I'm not sure if the use of EMLA has previously been discussed on the message boards and if it has, I apologize for duplication. I merely felt like I should add my two cents worth.

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3. http://www.emla-us.com/facts/ (LINK IS DEAD) so I added article, Using EMLA presurgical? Or maybe biopsy? Not sure but interesting...Dee

( EMLA = LIDOCAINE 2.5% & PRILOCAINE 2.5%

EMLA is a unique product that numbs your child's skin at the injection site and makes needle insertions and other procedures less painful. EMLA can only be prescribed by your child's doctor, but can easily be applied at home before the procedure.

Applying EMLA

EMLA Cream or EMLA Anesthetic Disc should be applied 1 hour before the shot or needle procedure. Satisfactory numbing of the skin occurs 1 hour after application, reaches a maximum at 2 to 3 hours (1 hour for children less than 3 months), and lasts for 1 to 2 hours after removal. This timing makes it convenient to apply EMLA at home prior to appointment.

Who can use EMLA?EMLA can be used for most children, including infants at least 37 weeks gestation. However, it should not be used in children with rare condition of congenital or idiopathic methemoglobinemia, or in infants under the age of 12 months who are receiving treatment with methemoglobin-inducing agents. It should also not be used in children with sensitivity to lidocaine or prilocaine, or any other component of the product. If you have any questions as to whether or not EMLA is right for your child, please consult your child's doctor.

Repeated UseYou can use EMLA for repeated procedures in the same place on his or her skin without the skin becoming permanently numb. The numbing effect of EMLA goes away completely a few hours after each application, whether it's been used at the same site or not.

Satisfactory numbing of the skin occurs 1 hour after application, reaches a maximum at 2 to 3 hours (1 hour for children less than 3 months), and lasts for 1 to 2 hours after removal. This timing makes it convenient to apply EMLA at home prior to appointment.

Safe to Touch?Since it takes time for EMLA to work, simply touching the Anesthetic Disc will not cause the area of touch to become numb, if EMLA is accidentally smeared on another part of the skin, just wipe it off.

Accidental ingestion of EMLA may be toxic. Call your local Poison Control Center and your doctor.

If EMLA comes in contact with your child's eyes, immediately rinse the eye with water; do not touch or rub the eye. Call your local emergency service or Poison Control Center and your doctor.

In adults, prior to procedure, squeeze out a dollop of EMLA Cream (1/2 of a 5-g tube) directly onto the skin. EMLA Cream may be left in place for up to 3 hours without diminishing its effectiveness. For pediatric patients, apply ONLY as prescribed by a physician.

Immediately before the procedure (at least 60 minutes after EMLA Cream has been applied), remove the dressing and cream. Clean entire area as usual and begin procedure.

Be sure to allow EMLA Cream to remain in a thick layer, DO NOT rub it in. Keep away from eyes and children.

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LAST ONE....

4.

Also here's another article about injections with a steroid and lidocaine forvestibulitis you might be interested in.

Dee

Journal of Lower Genital Tract Disease Volume 6 Issue 1 Page 62 - January 2002 Treatment of Vulvar Vestibulitis with Submucous Infiltrations ofMethylprednisolone and Lidocaine

F Murina, P Tassan, P i, V Bianco This group from Italy gave subcutaneous injections of 40 mg ofmethylprednisolone acetate and 10 mg of lidocaine cloridrate in 10 ml ofnormal saline into the vulvar vestibule in 22 women with vulvarvestibulitis. Injections were divided into equal parts between threesites, described as 4 o'clock, 8 o'clock, and around the posteriorfourchette. Follow up occurred monthly for three months, then after sixand nine months. Fourteen women had 12 months and five women 24 months of followup. Fifteen women (68) responded favorably to treatment, 32 withcomplete remission. Remission of symptoms occurred about 15 days aftertreatment. Five patients relapsed after one year and responded withimmediate remission when treated with a 0.5 ml infiltration. Nonerequired therapy after the 12th month. Comment: "Vulvar vestibulitis syndrome is difficult for patients andpractitioners with a myriad of treatments including oceans of lotionsand potions and notions about what should make this go away. Long-term antifungal therapies, steroid creams, sex hormonecreams, topical analgesics, diets, dietary supplements, capsacin, laser,antidepressants, anticonvulsants, musculoskeletal therapies, surgeriesof various kinds, and many other things have been tried as treatments. This extended case report suggests a good possible therapy that wouldbe readily available.>

Here are some other names of topical anesthetics I added too for what it's worth. ; )

Benzocaine · Americaine, Anacaine, Dermacoat, Hurricane, LagolButamben · Butesin PicrateLidocaine · Dermaflex, Ela-Max, XylocainePramoxine · Itch-X, PrameGel, Prax, Tronolane, TronothaneTetracaine · Pontocaine, Viractin

Hope that's of some help, and apologize for the length.

Hugs

Dee~ ; )