Re: Gastrointestinal/Dermatologic Disorders and skin problems?

[Guest guest]

Hey all,

I thought this information was fascinating!

I have had pretty bad skin problems (acne/pustules) since I have had

PSC (11 yrs). It increases in severity if I eat something I'm

allergic to, eat sugar, or am taking Androgel (because I had a very

low testosterone).

Since my skin has been pretty broken out lately and a little itchy

right now so I'm wondering if the psych meds (recently added new

ones) are doing that or if I just haven't been taking enough benadryl

(seems to help skin). In any case, no G.I. has ever helped me one bit

with my skin, and I've showed them all and asked for help. Some refer

me to dermatologists, who just want to give me more antibiotics

(pretty much useless for me at this point). That to me is like

treating the SYMPTOMS of the underlying problem. Its not the worst

its ever been at least

So if anyone else has skin problems I would be glad to talk about it

with you.

If anyone wants to take a look, I would be glad to send a picture via

email. My email is jarad_patko@... thanks for listening!

Jarad, 27 male

PSC dx 1996

UC dx 1999

J-pouch 2002-3 (pouchitis varies)

Food allergies (soy nuts gluten) dx 2004

Super low testosterone level dx 2006

Back surgery for 2 herniated discs 2007

>

>

> Gastrointestinal Manifestations of Dermatologic Disorders

>

> Helen M. Shieldslow

> Harvard Medical School, Somerville, Massachusetts

>

> September 4, 2007.

>

> The skin and the gastrointestinal tract may be affected

concurrently

> by the same diseases. Pathogenetically, these conditions may be

> primarily dermatologic diseases involving the gastrointestinal

(GI)

> tract or systemic diseases involving the skin, GI tract, and liver

> simultaneously. The correct diagnosis of such conditions relies on

the

> ability of the gastroenterologist to recognize the underlying

> dermatologic disorder. The goal of this clinical review article is

to

> increase gastroenterologists' awareness and understanding of some

of

> these conditions. Case vignettes are presented and the relevant

> literature reviewed for epidermolysis bullosa, mastocytosis,

> hereditary hemorrhagic telangiectasia, and melanoma. This review

> focuses on increasing gastroenterologists' ability to recognize,

> diagnose, comprehend, and manage patients with these dermatologic

> conditions who have GI manifestations. Advances in molecular

genetics

> that provide insight into the underlying pathophysiology and

> histopathology of these lesions are highlighted.

>

[Guest guest]

I have been also struggling with skin issues and no one seems to listen. My GI is sending me to a dermatolgist to see if I have developed an allergy to something. But it is very frustrating I agree. He had given me a prescription for adirax (didn't help my skin problems but maybe helps me sleep) my priimary care MD gave me a prescription for eucerin with steroids (no help) the liver specialist told me to use Sarna cream (no help). If the dermatologist doesn't find anything I guess the next step is trying zoloft. They say there are recent studies to show that may help. STILL ITCHING AND GOING CRAZY......jarad_patko wrote: Hey all,I thought this information was fascinating! I have had pretty bad skin problems (acne/pustules) since I have had PSC (11 yrs). It increases in severity if I eat something I'm allergic to, eat sugar, or am taking Androgel (because I had a very low testosterone).Since my skin has been pretty broken out lately and a little itchy right now so I'm wondering if the psych meds (recently added new ones) are doing that or if I just haven't been taking enough benadryl (seems to help skin). In any case, no G.I. has ever helped me one bit with my skin, and I've showed them all and asked for help. Some refer me to dermatologists, who just want to give me more antibiotics (pretty much useless for me at this point). That to me is like treating the SYMPTOMS of the underlying problem. Its not the worst its ever been at

least… So if anyone else has skin problems I would be glad to talk about it with you.If anyone wants to take a look, I would be glad to send a picture via email. My email is jarad_patko (AT) yahoo (DOT) com thanks for listening!Jarad, 27 malePSC dx 1996UC dx 1999J-pouch 2002-3 (pouchitis varies)Food allergies (soy nuts gluten) dx 2004Super low testosterone level dx 2006Back surgery for 2 herniated discs 2007>> > Gastrointestinal Manifestations of Dermatologic Disorders> > Helen M. Shieldslow> Harvard Medical School, Somerville, Massachusetts> > September 4, 2007.> > The skin and the gastrointestinal tract may be affected concurrently > by the same diseases.

Pathogenetically, these conditions may be > primarily dermatologic diseases involving the gastrointestinal (GI) > tract or systemic diseases involving the skin, GI tract, and liver > simultaneously. The correct diagnosis of such conditions relies on the > ability of the gastroenterologist to recognize the underlying > dermatologic disorder. The goal of this clinical review article is to > increase gastroenterologists' awareness and understanding of some of > these conditions. Case vignettes are presented and the relevant > literature reviewed for epidermolysis bullosa, mastocytosis, > hereditary hemorrhagic telangiectasia, and melanoma. This review > focuses on increasing gastroenterologists' ability to recognize, > diagnose, comprehend, and manage patients with these dermatologic > conditions who have GI manifestations. Advances in molecular genetics >

that provide insight into the underlying pathophysiology and > histopathology of these lesions are highlighted.>

Luggage? GPS? Comic books?

Check out fitting gifts for grads at Yahoo! Search.

[Guest guest]

> I have been also struggling with skin issues and no one seems to

listen. My GI is sending me to a dermatolgist to see if I have

developed an allergy to something. But it is very frustrating I

agree. He had given me a prescription for adirax (didn't help my skin

problems but maybe helps me sleep) my priimary care MD gave me a

prescription for eucerin with steroids (no help) the liver specialist

told me to use Sarna cream (no help). If the dermatologist doesn't

find anything I guess the next step is trying zoloft. They say there

are recent studies to show that may help. STILL ITCHING AND GOING

CRAZY......

> (seems to help skin). In any case, no G.I. has ever helped me one

bit with my skin, and I've showed them all and asked for help. Some

refer me to dermatologists, who just want to give me more

antibiotics (pretty much useless for me at this point). That to me is

like treating the SYMPTOMS of the underlying problem. Its not the

worst its ever been at least…

I'm just popping in after another little hiatus (I post in " waves " ...

have some serious catching up to do) and wanted to reply to this post

on the off-chance I might have something useful to contribute. My

son began having issues with severe dandruff (like oatmeal

flakes...caked layers of it) about a year before his PSC and IBD

diagnoses and we've never been able to clear it up, just lessen it

(different T-gels). He also started having hives and itching like

crazy right around the time of his diagnoses. That we have finally

reigned in. His Allergist is also an Immunologist (he did not see a

dermatologist) and eventually he ran a blood test to check for

autoimmune hives (CU Index / High Affinity FcERI Receptor also w/

TPO, Thyroglobulin ABS, TSH, and sedimentation rate ESR). The hives

were fixed first, but the itch took longer to get under control and

only recently our son has had genuine relief. He takes a mix of 2

allergy and 1 asthma med for his autoimmune hives and the combo has

worked --60mg allegra in the a.m. , and 5mg zyrtec & 10mg singulair

together in the p.m. He also gets some little, raised knobby things

on his elbows (--lotions up every day and night w/ aveeno, so it

isn't dry skin). Anyway, the hives and itch getting reigned in has

been wonderful for our son and I'd suggest the autoimmune

hives/urticaria blood test to others who are having trouble with

rashes, hives, or itching that isn't getting taken care of,

diagnosed, etc. Not all insurers covers the test. Our local

hospital the Allergist/Immun works out of (Sutter in California) did

not offer it --to families that didn't have a PPO.

And, good luck!

Meghan, mom to (almost 13yo) Wyatt: PSC 1/07, FAP 8/01, IBD 1 & 6/07,

autoim hives 6/07

[Guest guest]

Thanks for sharing! Interesting how we have the " allergy " connection

in common, except I take lots of benadryl.

>

> > I have been also struggling with skin issues and no one seems to

> listen. My GI is sending me to a dermatolgist to see if I have

> developed an allergy to something. But it is very frustrating I

> agree. He had given me a prescription for adirax (didn't help my

skin

> problems but maybe helps me sleep) my priimary care MD gave me a

> prescription for eucerin with steroids (no help) the liver

specialist

> told me to use Sarna cream (no help). If the dermatologist doesn't

> find anything I guess the next step is trying zoloft. They say

there

> are recent studies to show that may help. STILL ITCHING AND GOING

> CRAZY......

> > (seems to help skin). In any case, no G.I. has ever helped me one

> bit with my skin, and I've showed them all and asked for help. Some

> refer me to dermatologists, who just want to give me more

> antibiotics (pretty much useless for me at this point). That to me

is

> like treating the SYMPTOMS of the underlying problem. Its not the

> worst its ever been at least…

>

> I'm just popping in after another little hiatus (I post

in " waves " ...

> have some serious catching up to do) and wanted to reply to this

post

> on the off-chance I might have something useful to contribute. My

> son began having issues with severe dandruff (like oatmeal

> flakes...caked layers of it) about a year before his PSC and IBD

> diagnoses and we've never been able to clear it up, just lessen it

> (different T-gels). He also started having hives and itching like

> crazy right around the time of his diagnoses. That we have finally

> reigned in. His Allergist is also an Immunologist (he did not see

a

> dermatologist) and eventually he ran a blood test to check for

> autoimmune hives (CU Index / High Affinity FcERI Receptor also w/

> TPO, Thyroglobulin ABS, TSH, and sedimentation rate ESR). The

hives

> were fixed first, but the itch took longer to get under control and

> only recently our son has had genuine relief. He takes a mix of 2

> allergy and 1 asthma med for his autoimmune hives and the combo has

> worked --60mg allegra in the a.m. , and 5mg zyrtec & 10mg singulair

> together in the p.m. He also gets some little, raised knobby

things

> on his elbows (--lotions up every day and night w/ aveeno, so it

> isn't dry skin). Anyway, the hives and itch getting reigned in has

> been wonderful for our son and I'd suggest the autoimmune

> hives/urticaria blood test to others who are having trouble with

> rashes, hives, or itching that isn't getting taken care of,

> diagnosed, etc. Not all insurers covers the test. Our local

> hospital the Allergist/Immun works out of (Sutter in California)

did

> not offer it --to families that didn't have a PPO.

> And, good luck!

> Meghan, mom to (almost 13yo) Wyatt: PSC 1/07, FAP 8/01, IBD 1 & 6/07,

> autoim hives 6/07

>

[Guest guest]

Thank you so much for your input. I started getting the hives when my PSC kicked into full gear in March 2006 and have been struggling with them ever since. I defintely will look into this.wymom94 wrote: > I have been also struggling with skin issues and no one seems to listen. My GI is sending me to a dermatolgist to see if I have developed an allergy to something. But it is very frustrating I agree. He had given me a prescription for adirax (didn't help my skin problems but maybe helps me sleep) my priimary

care MD gave me a prescription for eucerin with steroids (no help) the liver specialist told me to use Sarna cream (no help). If the dermatologist doesn't find anything I guess the next step is trying zoloft. They say there are recent studies to show that may help. STILL ITCHING AND GOING CRAZY......> (seems to help skin). In any case, no G.I. has ever helped me one bit with my skin, and I've showed them all and asked for help. Some refer me to dermatologists, who just want to give me more antibiotics (pretty much useless for me at this point). That to me is like treating the SYMPTOMS of the underlying problem. Its not the worst its ever been at least… I'm just popping in after another little hiatus (I post in "waves"... have some serious catching up to do) and wanted to reply to this post on the off-chance I might have something useful to contribute. My son began having issues with severe dandruff (like

oatmeal flakes...caked layers of it) about a year before his PSC and IBD diagnoses and we've never been able to clear it up, just lessen it (different T-gels). He also started having hives and itching like crazy right around the time of his diagnoses. That we have finally reigned in. His Allergist is also an Immunologist (he did not see a dermatologist) and eventually he ran a blood test to check for autoimmune hives (CU Index / High Affinity FcERI Receptor also w/ TPO, Thyroglobulin ABS, TSH, and sedimentation rate ESR). The hives were fixed first, but the itch took longer to get under control and only recently our son has had genuine relief. He takes a mix of 2 allergy and 1 asthma med for his autoimmune hives and the combo has worked --60mg allegra in the a.m. , and 5mg zyrtec & 10mg singulair together in the p.m. He also gets some little, raised knobby things on his elbows (--lotions up every day and night w/

aveeno, so it isn't dry skin). Anyway, the hives and itch getting reigned in has been wonderful for our son and I'd suggest the autoimmune hives/urticaria blood test to others who are having trouble with rashes, hives, or itching that isn't getting taken care of, diagnosed, etc. Not all insurers covers the test. Our local hospital the Allergist/Immun works out of (Sutter in California) did not offer it --to families that didn't have a PPO.And, good luck!Meghan, mom to (almost 13yo) Wyatt: PSC 1/07, FAP 8/01, IBD 1 & 6/07, autoim hives 6/07

Looking for a deal? Find great prices on flights and hotels with Yahoo! FareChase.

[Guest guest]

I am very glad to see this topic being discussed as I too have

recently been having lots of episodes of hives. I have had asthma

and allergies my entire life. Although interestingly my asthma has

now totally cleared up. Which is strange because it was severe and

almost cost me my life more than once. I guess my body has shifted

from attacking my lungs to attacking my liver! Anyways, through all

my years of asthma and allergies I never once had hives. And now

all of a sudden I am getting hives quite often. I was also recently

diagnosed (by my allergist) as having this weird condition where I

can get a rash and hives wherever I am wearing constrictive

clothing. But I don't think this is related to the hives I am

getting (which are primarily on my forearms and legs).

Thanks again for the info. I am glad we have each other!

Amy

PSC July 07'

> I have been also

struggling with skin issues and no one seems to

> listen. My GI is sending me to a dermatolgist to see if I have

> developed an allergy to something. But it is very frustrating I

> agree. He had given me a prescription for adirax (didn't help my

skin

> problems but maybe helps me sleep) my priimary care MD gave me a

> prescription for eucerin with steroids (no help) the liver

specialist

> told me to use Sarna cream (no help). If the dermatologist doesn't

> find anything I guess the next step is trying zoloft. They say

there

> are recent studies to show that may help. STILL ITCHING AND GOING

> CRAZY......

> > (seems to help skin). In any case, no G.I. has ever helped me

one

> bit with my skin, and I've showed them all and asked for help.

Some

> refer me to dermatologists, who just want to give me more

> antibiotics (pretty much useless for me at this point). That to me

is

> like treating the SYMPTOMS of the underlying problem. Its not the

> worst its ever been at least

>

> I'm just popping in after another little hiatus (I post

in " waves " ...

> have some serious catching up to do) and wanted to reply to this

post

> on the off-chance I might have something useful to contribute. My

> son began having issues with severe dandruff (like oatmeal

> flakes...caked layers of it) about a year before his PSC and IBD

> diagnoses and we've never been able to clear it up, just lessen it

> (different T-gels). He also started having hives and itching like

> crazy right around the time of his diagnoses. That we have finally

> reigned in. His Allergist is also an Immunologist (he did not see

a

> dermatologist) and eventually he ran a blood test to check for

> autoimmune hives (CU Index / High Affinity FcERI Receptor also w/

> TPO, Thyroglobulin ABS, TSH, and sedimentation rate ESR). The

hives

> were fixed first, but the itch took longer to get under control

and

> only recently our son has had genuine relief. He takes a mix of 2

> allergy and 1 asthma med for his autoimmune hives and the combo

has

> worked --60mg allegra in the a.m. , and 5mg zyrtec & 10mg

singulair

> together in the p.m. He also gets some little, raised knobby

things

> on his elbows (--lotions up every day and night w/ aveeno, so it

> isn't dry skin). Anyway, the hives and itch getting reigned in has

> been wonderful for our son and I'd suggest the autoimmune

> hives/urticaria blood test to others who are having trouble with

> rashes, hives, or itching that isn't getting taken care of,

> diagnosed, etc. Not all insurers covers the test. Our local

> hospital the Allergist/Immun works out of (Sutter in California)

did

> not offer it --to families that didn't have a PPO.

> And, good luck!

> Meghan, mom to (almost 13yo) Wyatt: PSC 1/07, FAP 8/01, IBD

1 & 6/07,

> autoim hives 6/07

>

>

>

>

>

>

>

> ---------------------------------

> Looking for a deal? Find great prices on flights and hotels with

Yahoo! FareChase.

>

[Guest guest]

Wow I forgot to mention I have also had allergies and severe asthma

as a child. That seemed to go away and then I had psc. I've had the

broken out skin since before I was actually diagnosed with psc (1996)

My hives are on my chest arms and back, there are next to none on my

lower abdomen or legs. Thanks for sharing, this is great to have the

support! Peace,

Jarad

> I have been also

> struggling with skin issues and no one seems to

> > listen. My GI is sending me to a dermatolgist to see if I have

> > developed an allergy to something. But it is very frustrating I

> > agree. He had given me a prescription for adirax (didn't help my

> skin

> > problems but maybe helps me sleep) my priimary care MD gave me a

> > prescription for eucerin with steroids (no help) the liver

> specialist

> > told me to use Sarna cream (no help). If the dermatologist

doesn't

> > find anything I guess the next step is trying zoloft. They say

> there

> > are recent studies to show that may help. STILL ITCHING AND GOING

> > CRAZY......

> > > (seems to help skin). In any case, no G.I. has ever helped me

> one

> > bit with my skin, and I've showed them all and asked for help.

> Some

> > refer me to dermatologists, who just want to give me more

> > antibiotics (pretty much useless for me at this point). That to

me

> is

> > like treating the SYMPTOMS of the underlying problem. Its not the

> > worst its ever been at least

> >

> > I'm just popping in after another little hiatus (I post

> in " waves " ...

> > have some serious catching up to do) and wanted to reply to this

> post

> > on the off-chance I might have something useful to contribute. My

> > son began having issues with severe dandruff (like oatmeal

> > flakes...caked layers of it) about a year before his PSC and IBD

> > diagnoses and we've never been able to clear it up, just lessen

it

> > (different T-gels). He also started having hives and itching like

> > crazy right around the time of his diagnoses. That we have

finally

> > reigned in. His Allergist is also an Immunologist (he did not see

> a

> > dermatologist) and eventually he ran a blood test to check for

> > autoimmune hives (CU Index / High Affinity FcERI Receptor also w/

> > TPO, Thyroglobulin ABS, TSH, and sedimentation rate ESR). The

> hives

> > were fixed first, but the itch took longer to get under control

> and

> > only recently our son has had genuine relief. He takes a mix of 2

> > allergy and 1 asthma med for his autoimmune hives and the combo

> has

> > worked --60mg allegra in the a.m. , and 5mg zyrtec & 10mg

> singulair

> > together in the p.m. He also gets some little, raised knobby

> things

> > on his elbows (--lotions up every day and night w/ aveeno, so it

> > isn't dry skin). Anyway, the hives and itch getting reigned in

has

> > been wonderful for our son and I'd suggest the autoimmune

> > hives/urticaria blood test to others who are having trouble with

> > rashes, hives, or itching that isn't getting taken care of,

> > diagnosed, etc. Not all insurers covers the test. Our local

> > hospital the Allergist/Immun works out of (Sutter in California)

> did

> > not offer it --to families that didn't have a PPO.

> > And, good luck!

> > Meghan, mom to (almost 13yo) Wyatt: PSC 1/07, FAP 8/01, IBD

> 1 & 6/07,

> > autoim hives 6/07

> >

> >

> >

> >

> >

> >

> >

> > ---------------------------------

> > Looking for a deal? Find great prices on flights and hotels with

> Yahoo! FareChase.

> >

>