The first reported case of lichen planus following inactivated influenza vaccination.

[Guest guest]

J Drugs Dermatol. 2007 May;6(5):536-8.

The first reported case of lichen planus following inactivated influenza vaccination.

Akay BN, Arslan A, Cekirge S, Erkin G, Anadolu-Brasie R.

Department of Dermatology, Ankara, Turkey.

Lichen planus (LP) is an idiopathic,

inflammatory, pruritic dermatosis

of unknown origin. An increased prevalence of a wide

range of diseases such as viral hepatitis C, hepatitis B, primary sclerosing cholangitis, and

primary biliary cirrhosis have been associated with LP. Recently,

LP has been reported following administration of different types of hepatis B vaccines but a relationship with an inactivated

influenza vaccine (Fluarix, GlaxoKline)

has not been reported previously. We present a case of

generalized LP manifesting 7 days after the first 0.5-ml dose of influenza

vaccine, administered via deltoid injection. LP is

possibly a viral antigen-triggered inflammatory skin condition, the

pathogenesis of which needs to be further explored.

With love, Barb in Texas - Together in the Fight, Whatever it Takes!

Son Ken (33) UC 91 - PSC 99 - Tx 6/21 & 6/30/07 @ Baylor in Dallas